| Everglades virus | |
|---|---|
|   | |
| CryoEM reconstruction of the Everglades Virus. EMDB entry EMD-5563 [1] | |
| Virus classification   | |
| (unranked): | Virus | 
| Realm: | Riboviria | 
| Kingdom: | Orthornavirae | 
| Phylum: | Kitrinoviricota | 
| Class: | Alsuviricetes | 
| Order: | Martellivirales | 
| Family: | Togaviridae | 
| Genus: | Alphavirus | 
| Species: | Alphavirus everglades | 
Everglades virus (EVEV) is an alphavirus included in the Venezuelan equine encephalitis virus complex. The virus circulates among rodents and vector mosquitoes and sometimes infects humans, causing a febrile illness with occasional neurological manifestations. [2] [3] Although it is said to be rare in humans it is still debated if this is the case because of the possibility of underdiagnosing as well as being a unrecognized cause of other illnesses. [4] The virus is named after the Everglades, a region of subtropical wetlands in southern Florida. The virus is endemic to the U.S. state of Florida, where its geographic range mirrors that of the mosquito species Culex cedecei . [2] Hispid cotton rat and cotton mouse are considered important reservoir hosts of Everglades virus. Most clinical cases of infection occur in and around the city of Miami. [3] The abundance in clinical cases in certain parts of Florida comes from many factors such as population density and proximity to the hosts and their ecosystem. [5]
Symptoms of infection include: [6]
The virus is transmitted by the bite of infected mosquitoes of the genus Culex , [7] specifically Culex cedecei. [2] [8]