Exosome component 10

Last updated
EXOSC10
Protein EXOSC10 PDB 2cpr.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases EXOSC10 , PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4, exosome component 10
External IDs OMIM: 605960; MGI: 1355322; HomoloGene: 31105; GeneCards: EXOSC10; OMA:EXOSC10 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001001998
NM_002685

NM_016699
NM_001355489
NM_001355490

RefSeq (protein)

NP_001001998
NP_002676

NP_057908
NP_001342418
NP_001342419

Location (UCSC) Chr 1: 11.07 – 11.1 Mb Chr 4: 148.64 – 148.67 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which (sometimes called PM/Scl-100) is part of the exosome complex and is an autoantigen is patients with certain auto immune diseases, most notably scleromyositis. [5]


References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000171824 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000017264 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: EXOSC10 exosome component 10".

Further reading