FAM57B

TLCD3B
Identifiers
Aliases	TLCD3B , FP1188, family with sequence similarity 57 member B, FAM57B, TLC domain ceramide synthase 3B, TLC domain containing 3B, CORD22
External IDs	OMIM: 615175; MGI: 1916202; HomoloGene: 69491; GeneCards: TLCD3B; OMA:TLCD3B - orthologs
Gene location (Human) Chr. Chromosome 16 (human) [1] Band 16p11.2 Start 30,024,427 bp [1] End 30,052,978 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 F3 Start 126,396,840 bp [2] End 126,429,391 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis right testis right hemisphere of cerebellum ganglionic eminence vena cava right frontal lobe pons cingulate gyrus anterior cingulate cortex prefrontal cortex Top expressed in neural layer of retina Rostral migratory stream deep cerebellar nuclei retinal pigment epithelium pontine nuclei cerebellar vermis lobe of cerebellum medial vestibular nucleus inferior colliculi epithelium of lens More reference expression data BioGPS n/a
Gene ontology Molecular function sphingosine N-acyltransferase activity Cellular component integral component of membrane Golgi membrane Golgi apparatus endoplasmic reticulum membrane endoplasmic reticulum membrane Biological process ceramide biosynthetic process negative regulation of fat cell differentiation lipid metabolism Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 83723 68952 Ensembl ENSG00000149926 ENSMUSG00000058966 UniProt Q71RH2 Q7TNV1 RefSeq (mRNA) NM_031478 NM_001318504 NM_001352173 NM_001146347 NM_026884 NM_029978 RefSeq (protein) NP_001305433 NP_113666 NP_001339102 NP_001139819 NP_081160 NP_084254 Location (UCSC) Chr 16: 30.02 – 30.05 Mb Chr 7: 126.4 – 126.43 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Protein FAM57B is a protein that in humans is encoded by the FAM57B gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000149926 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000058966 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
6. "Entrez Gene: FAM57B family with sequence similarity 57, member B".

Further reading

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi: 10.1073/pnas.0404089101 . PMC   524842 . PMID   15498874.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.