FLRT2

Last updated
FLRT2
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases FLRT2 , fibronectin leucine rich transmembrane protein 2
External IDs OMIM: 604807; MGI: 3603594; HomoloGene: 8291; GeneCards: FLRT2; OMA:FLRT2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001346143
NM_001346144
NM_001346145
NM_001346146
NM_013231

Contents

NM_201518

RefSeq (protein)

NP_001333072
NP_001333073
NP_001333074
NP_001333075
NP_037363

NP_958926

Location (UCSC) Chr 14: 85.53 – 85.65 Mb Chr 12: 95.66 – 95.75 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Fibronectin leucine-rich repeat transmembrane protein FLRT2 is a protein that in humans is encoded by the FLRT2 gene. [5] [6] [7]

Function

This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRT family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. [7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000185070 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000047414 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Lacy SE, Bönnemann CG, Buzney EA, Kunkel LM (December 1999). "Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins". Genomics. 62 (3): 417–26. doi:10.1006/geno.1999.6033. PMID   10644439.
  6. Haines BP, Wheldon LM, Summerbell D, Heath JK, Rigby PW (September 2006). "Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development". Developmental Biology. 297 (1): 14–25. doi:10.1016/j.ydbio.2006.04.004. PMID   16872596.
  7. 1 2 "Entrez Gene: FLRT2 fibronectin leucine rich transmembrane protein 2".

Further reading