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In biochemistry, flow birefringence is a hydrodynamic technique for measuring the rotational diffusion constants (or, equivalently, the rotational drag coefficients). The birefringence of a solution sandwiched between two concentric cylinders is measured as a function of the difference in rotational speed between the inner and outer cylinders. The flow tends to orient an ellipsoidal particle (typically, a protein, virus, etc.) in one direction, whereas rotational diffusion (tumbling) causes the molecule to become disoriented. The equilibrium between these two processes as a function of the flow provides a measure of the axial ratio of the ellipsoidal particle.
Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms. Biochemical processes give rise to the complexity of life.
Birefringence is the optical property of a material having a refractive index that depends on the polarization and propagation direction of light. These optically anisotropic materials are said to be birefringent. The birefringence is often quantified as the maximum difference between refractive indices exhibited by the material. Crystals with non-cubic crystal structures are often birefringent, as are plastics under mechanical stress.
Axial ratio, for any structure or shape with two or more axes, is the ratio of the length of those axes to each other - the longer axis divided by the shorter.
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Anisotropy, is the property of being directionally dependent, which implies different properties in different directions, as opposed to isotropy. It can be defined as a difference, when measured along different axes, in a material's physical or mechanical properties
Molecular diffusion, often simply called diffusion, is the thermal motion of all particles at temperatures above absolute zero. The rate of this movement is a function of temperature, viscosity of the fluid and the size (mass) of the particles. Diffusion explains the net flux of molecules from a region of higher concentration to one of lower concentration. Once the concentrations are equal the molecules continue to move, but since there is no concentration gradient the process of molecular diffusion has ceased and is instead governed by the process of self-diffusion, originating from the random motion of the molecules. The result of diffusion is a gradual mixing of material such that the distribution of molecules is uniform. Since the molecules are still in motion, but an equilibrium has been established, the end result of molecular diffusion is called a "dynamic equilibrium". In a phase with uniform temperature, absent external net forces acting on the particles, the diffusion process will eventually result in complete mixing.
Polarization is a property applying to transverse waves that specifies the geometrical orientation of the oscillations. In a transverse wave, the direction of the oscillation is perpendicular to the direction of motion of the wave. A simple example of a polarized transverse wave is vibrations traveling along a taut string (see image); for example, in a musical instrument like a guitar string. Depending on how the string is plucked, the vibrations can be in a vertical direction, horizontal direction, or at any angle perpendicular to the string. In contrast, in longitudinal waves, such as sound waves in a liquid or gas, the displacement of the particles in the oscillation is always in the direction of propagation, so these waves do not exhibit polarization. Transverse waves that exhibit polarization include electromagnetic waves such as light and radio waves, gravitational waves, and transverse sound waves in solids. In some types of transverse waves, the wave displacement is limited to a single direction, so these also do not exhibit polarization; for example, in surface waves in liquids, the wave displacement of the particles is always in a vertical plane.
A viscometer is an instrument used to measure the viscosity of a fluid. For liquids with viscosities which vary with flow conditions, an instrument called a rheometer is used. Thus, a rheometer can be considered as a special type of viscometer. Viscometers only measure under one flow condition.
In fluid dynamics, a vortex is a region in a fluid in which the flow revolves around an axis line, which may be straight or curved. Vortices form in stirred fluids, and may be observed in smoke rings, whirlpools in the wake of a boat, and the winds surrounding a tropical cyclone, tornado or dust devil.
In continuum mechanics, stress is a physical quantity that expresses the internal forces that neighbouring particles of a continuous material exert on each other, while strain is the measure of the deformation of the material. For example, when a solid vertical bar is supporting an overhead weight, each particle in the bar pushes on the particles immediately below it. When a liquid is in a closed container under pressure, each particle gets pushed against by all the surrounding particles. The container walls and the pressure-inducing surface push against them in (Newtonian) reaction. These macroscopic forces are actually the net result of a very large number of intermolecular forces and collisions between the particles in those molecules. Stress is frequently represented by a lowercase Greek letter sigma (σ).
A hydrocyclone is a device to classify, separate or sort particles in a liquid suspension based on the ratio of their centripetal force to fluid resistance. This ratio is high for dense and coarse particles, and low for light and fine particles. Hydrocyclones also find application in the separation of liquids of different densities.
In industrial process engineering, mixing is a unit operation that involves manipulation of a heterogeneous physical system with the intent to make it more homogeneous. Familiar examples include pumping of the water in a swimming pool to homogenize the water temperature, and the stirring of pancake batter to eliminate lumps (deagglomeration). Mixing is performed to allow heat and/or mass transfer to occur between one or more streams, components or phases. Modern industrial processing almost always involves some form of mixing. Some classes of chemical reactors are also mixers. With the right equipment, it is possible to mix a solid, liquid or gas into another solid, liquid or gas. A biofuel fermenter may require the mixing of microbes, gases and liquid medium for optimal yield; organic nitration requires concentrated (liquid) nitric and sulfuric acids to be mixed with a hydrophobic organic phase; production of pharmaceutical tablets requires blending of solid powders. The opposite of mixing is segregation. A classical example of segregation is the brazil nut effect.
A gas centrifuge is a device that performs isotope separation of gases. A centrifuge relies on the principles of centripetal force accelerating molecules so that particles of different masses are physically separated in a gradient along the radius of a rotating container. A prominent use of gas centrifuges is for the separation of uranium-235 from uranium-238. The gas centrifuge was developed to replace the gaseous diffusion method of uranium-235 extraction. High degrees of separation of these isotopes relies on using many individual centrifuges arranged in cascade, that achieve successively higher concentrations. This process yields higher concentrations of uranium-235 while using significantly less energy compared to the gaseous diffusion process.
Polarimetry is the measurement and interpretation of the polarization of transverse waves, most notably electromagnetic waves, such as radio or light waves. Typically polarimetry is done on electromagnetic waves that have traveled through or have been reflected, refracted or diffracted by some material in order to characterize that object.
A rheometer is a laboratory device used to measure the way in which a liquid, suspension or slurry flows in response to applied forces. It is used for those fluids which cannot be defined by a single value of viscosity and therefore require more parameters to be set and measured than is the case for a viscometer. It measures the rheology of the fluid.
In optics, an index ellipsoid is a diagram of an ellipsoid that depicts the orientation and relative magnitude of refractive indices in a crystal .
Diffusion-weighted magnetic resonance imaging is the use of specific MRI sequences as well as software that generates images from the resulting data, that uses the diffusion of water molecules to generate contrast in MR images. It allows the mapping of the diffusion process of molecules, mainly water, in biological tissues, in vivo and non-invasively. Molecular diffusion in tissues is not free, but reflects interactions with many obstacles, such as macromolecules, fibers, and membranes. Water molecule diffusion patterns can therefore reveal microscopic details about tissue architecture, either normal or in a diseased state. A special kind of DWI, diffusion tensor imaging (DTI), has been used extensively to map white matter tractography in the brain.
In physics the Einstein relation is a previously unexpected connection revealed independently by William Sutherland in 1904, Albert Einstein in 1905, and by Marian Smoluchowski in 1906 in their papers on Brownian motion. The more general form of the equation is
In hydrodynamics, the Perrin friction factors are multiplicative adjustments to the translational and rotational friction of a rigid spheroid, relative to the corresponding frictions in spheres of the same volume. These friction factors were first calculated by Jean-Baptiste Perrin.
Dynamic light scattering (DLS) is a technique in physics that can be used to determine the size distribution profile of small particles in suspension or polymers in solution. In the scope of DLS, temporal fluctuations are usually analyzed by means of the intensity or photon auto-correlation function. In the time domain analysis, the autocorrelation function (ACF) usually decays starting from zero delay time, and faster dynamics due to smaller particles lead to faster decorrelation of scattered intensity trace. It has been shown that the intensity ACF is the Fourier transformation of the power spectrum, and therefore the DLS measurements can be equally well performed in the spectral domain. DLS can also be used to probe the behavior of complex fluids such as concentrated polymer solutions.
Rotational diffusion is a process by which the equilibrium statistical distribution of the overall orientation of particles or molecules is maintained or restored. Rotational diffusion is the counterpart of translational diffusion, which maintains or restores the equilibrium statistical distribution of particles' position in space.
In chaos theory and fluid dynamics, chaotic mixing is a process by which flow tracers develop into complex fractals under the action of a fluid flow. The flow is characterized by an exponential growth of fluid filaments. Even very simple flows, such as the blinking vortex, or finitely resolved wind fields can generate exceptionally complex patterns from initially simple tracer fields.
Membrane technology covers all engineering approaches for the transport of substances between two fractions with the help of permeable membranes. In general, mechanical separation processes for separating gaseous or liquid streams use membrane technology.