Established | 1970 |
---|---|
Research type | Basic research (non-clinical) |
Field of research |
|
Director | Dirk Schübeler |
Location | Basel, Switzerland |
Affiliations | University of Basel |
Website | www |
The Friedrich Miescher Institute for Biomedical Research (FMI) is a biomedical research institute founded in 1970. Based in Basel, Switzerland, the FMI is affiliated with the University of Basel and the Novartis Institutes for BioMedical Research (NIBR). It is named after Friedrich Miescher. As of 2021 [update] , the FMI has around 340 collaborators, of which 20 are research group leaders, over 80 are postdoctoral collaborators and over 80 are postgraduate students participating in the FMI International PhD Program. The FMI is directed by Dirk Schübeler.
The FMI is member of EU-LIFE, an alliance of leading life sciences research centres in Europe. [1]
The FMI is devoted to the pursuit of fundamental biomedical research. Areas of research are neurobiology, genome regulation, and multicellular systems.
Research is carried out in 20 independent but highly interactive[ citation needed ] research groups. In addition, several cutting-edge technology platforms - including microscopy & imaging, computational biology, functional genomics, proteomics, structural biology and more - support the research activities. [ citation needed ]
From 2014 to 2019, the FMI had the highest success rate for ERC grant applications of all European institutions. [2]
The FMI is an affiliated institute of the University of Basel. [14] It provides biomedical research and career training for its 80-100 PhD students at a time. FMI selects its highly international student body during a twice-yearly interview-based selection program. [15] Most FMI group leaders have adjunct or full professorships at the University of Basel in the Natural Sciences Faculty. In particular, the FMI participates actively in the teaching program of the Biozentrum of the University of Basel.
The FMI also offers training in biomedical research to postdoctoral fellows. It was designated by a survey of The Scientist in 2012, as the “best place for postdoctoral training” outside of the US. [16] [17]
A goal of the FMI is the patenting of its discoveries and implementation of its basic research into pharmaceutical development. [18]
The Friedrich Miescher Institute for Biomedical Research is named after the Basel scientist Friedrich Miescher who discovered nucleic acids in the mid-19th century.
The FMI was founded in 1970, a hundred years after Miescher's discovery, as a collaborative effort of two Basel-based pharmaceutical companies, Ciba Aktiengesellschaft and J. R. Geigy Ltd. [19] The founding charter describes the aims of the institute as to “pursue and promote basic research in the fields of biochemistry and medicine…“ and “…to provide young scientists from all over the world with an opportunity to participate in scientific research.” [20] The Founding Director was Professor Hubert Bloch (died 1974) who had been Director of Research at Ciba Aktiengesellschaft, and Professor of Microbiology and Immunology at the University of Basel. He was an expert in tuberculosis [21] [22] and was also instrumental in the founding of the Institut Suisse pour les Recherches Experimentales sur la Cancer (ISREC), Epalinges, Switzerland. Between 1997 and 2012, the FMI was part of the Novartis Research Foundation. [23] Since 2012 the FMI is an independent foundation. [24]
List of the successive directors of the Friedrich Miescher Institute for Biomedical Research:
The Friedrich Miescher Award is Switzerland's highest honor for up-and-coming biochemical researchers. The award is granted every year by the Swiss Society for Biochemistry [25] to the best scientific contribution in this field. Prize winners must be under 40 and must either be Swiss citizens or have conducted the prize-winning research in this country. The award was instituted in 1970, proposed and donated by the FMI. It is named after the Basel scientist who discovered DNA, Friedrich Miescher.
Johannes Friedrich Miescher was a Swiss physician and biologist. He was the first scientist to isolate nucleic acid in 1869. He also identified protamine and made a number of other discoveries.
The University of Basel is a university in Basel, Switzerland. Founded on 4 April 1460, it is Switzerland's oldest university and among the world's oldest surviving universities. The university is traditionally counted among the leading institutions of higher learning in the country.
Leland Harrison (Lee) Hartwell is former president and director of the Fred Hutchinson Cancer Research Center in Seattle, Washington. He shared the 2001 Nobel Prize in Physiology or Medicine with Paul Nurse and Tim Hunt, for their discoveries of protein molecules that control the division (duplication) of cells.
The SIB Swiss Institute of Bioinformatics is an academic not-for-profit foundation which federates bioinformatics activities throughout Switzerland.
The Basel Institute for Immunology (BII) was founded in 1969 as a basic research institute in immunology located at 487 Grenzacherstrasse, Basel, Switzerland on the Rhine River down the street from the main Hoffmann-La Roche campus near the Swiss-German border. The institute opened its doors in 1971.
Science and technology in Switzerland play an important role in the Swiss economy as very few natural resources are available in the country. The Swiss National Science Foundation, mandated by the Federal government, is the most important institute promoting scientific research.
The Biozentrum of the University of Basel specializes in basic molecular and biomedical research and teaching. Research includes the areas of cell growth and development, infection biology, neurobiology, structural biology and biophysics, and computational and systems biology. With 500 employees, the Biozentrum is the largest department at the University of Basel's Faculty of Science. It is home to 30 research groups with scientists from more than 40 nations.
Silvia Arber is a Swiss neurobiologist. She teaches and researches at both the Biozentrum of the University of Basel and the Friedrich Miescher Institute for Biomedical Research in Basel Switzerland.
Barbara HohnForMemRS is an Austrian molecular biologist, particularly known for her research into the Agrobacterium tumefaciens.
Michael Nip Hall is an American-Swiss molecular biologist and professor at the Biozentrum University of Basel, Switzerland.
Jean Pieters is a Dutch biochemist and Professor at the Biozentrum of the University of Basel, Switzerland.
Anthony Rex Hunter is a British-American biologist who is a Professor of Biology at the Salk Institute for Biological Studies and the University of California San Diego. His research publications list his name as Tony Hunter.
Susan M. Gasser is a Swiss molecular biologist. She was the Director of the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland, from 2004 - 2019, where she also led a research group from 2004 until 2021. She was in parallel Professor of molecular biology at the University of Basel until April 2021. Since January 2021, Susan Gasser is Director of the ISREC Foundation, based in Lausanne, and is Professor invité at the University of Lausanne in the Department of Fundamental Microbiology. She is an expert in quantitative biology and studies epigenetic inheritance and genome stability.
Ruth Chiquet-Ehrismann was a Swiss biochemist and cell biologist working on interactions in the extracellular matrix.
Owen Witte is an American physician-scientist at the University of California, Los Angeles. He is a distinguished professor of microbiology, immunology and molecular genetics in the David Geffen School of Medicine at UCLA, founding director of the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, and the UC Regents’ David Saxon Presidential Chair in developmental immunology (1989–present). Witte is also a Howard Hughes Medical Institute investigator (1986–present) and a member of the President's Cancer Panel. He also served on the Life Sciences jury for the Infosys Prize in 2013.
Jin Zhang is a Chinese-American biochemist. She is a professor of pharmacology, chemistry and biochemistry, and biomedical engineering at the University of California, San Diego.
Nadine Gogolla is a Research Group Leader at the Max Planck Institute of Neurobiology in Martinsried, Germany as well as an Associate Faculty of the Graduate School for Systemic Neuroscience. Gogolla investigates the neural circuits underlying emotion to understand how the brain integrates external cues, feeling states, and emotions to make calculated behavioral decisions. Gogolla is known for her discovery using machine learning and two-photon microscopy to classify mouse facial expressions into emotion-like categories and correlate these facial expressions with neural activity in the insular cortex.
Isabelle M. Mansuy is a professor in neuroepigenetics in the Medical Faculty of the University of Zurich and the Department of Health Science and Technology of the Swiss Federal Institute of Technology Zurich. She is known for her work on the mechanisms of epigenetic inheritance in relation to childhood trauma.
Dirk Schübeler is a German researcher, Director of the Friedrich Miescher Institute for Biomedical Research (FMI) and professor at the University of Basel. He is an expert in gene regulation.
Collin Yvès Ewald is a Swiss scientist investigating the molecular mechanisms of healthy aging. He is a molecular biologist and a professor at ETH Zurich, where he leads the Laboratory of Extracellular Matrix Regeneration. His research focuses on the remodeling of the extracellular matrix during aging and upon longevity interventions.