GLG1

GLG1
Identifiers
Aliases	GLG1 , CFR-1, ESL-1, MG-160, MG160, golgi glycoprotein 1
External IDs	OMIM: 600753; MGI: 104967; HomoloGene: 7533; GeneCards: GLG1; OMA:GLG1 - orthologs
Gene location (Human) Chr. Chromosome 16 (human) [1] Band 16q23.1 Start 74,447,427 bp [1] End 74,607,144 bp [1]
Gene location (Mouse) Chr. Chromosome 8 (mouse) [2] Band 8 E1|8 57.98 cM Start 111,881,053 bp [2] End 111,985,848 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium renal medulla nipple tibia pylorus cardia external globus pallidus corpus callosum ventral tegmental area spinal ganglia Top expressed in efferent ductule calvaria epithelium of lens Rostral migratory stream internal carotid artery ciliary body central gray substance of midbrain lacrimal gland right ventricle stroma of bone marrow More reference expression data BioGPS More reference expression data
Gene ontology Molecular function fibroblast growth factor binding signaling receptor binding Cellular component integral component of membrane plasma membrane Golgi apparatus extracellular exosome membrane Golgi membrane extracellular matrix Biological process bone morphogenesis negative regulation of protein processing regulation of chondrocyte differentiation negative regulation of transforming growth factor beta receptor signaling pathway leukocyte migration Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2734 20340 Ensembl ENSG00000090863 ENSMUSG00000003316 UniProt Q92896 Q61543 RefSeq (mRNA) NM_001145666 NM_001145667 NM_012201 NM_009149 NM_001368315 RefSeq (protein) NP_001139138 NP_001139139 NP_036333 NP_033175 NP_001355244 Location (UCSC) Chr 16: 74.45 – 74.61 Mb Chr 8: 111.88 – 111.99 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Golgi apparatus protein 1 is a protein that in humans is encoded by the GLG1 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000090863 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000003316 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Mourelatos Z, Gonatas JO, Nycum LM, Gonatas NK, Biegel JA (Feb 1996). "Assignment of the GLG1 gene for MGF-160, a fibroblast growth factor and E-selectin binding membrane sialoglycoprotein of the Golgi apparatus, to chromosome 16q22-q23 by fluorescence in situ hybridization". Genomics. 28 (2): 354–5. doi: 10.1006/geno.1995.1156 . PMID   8530051.
6. Steegmaier M, Levinovitz A, Isenmann S, Borges E, Lenter M, Kocher HP, Kleuser B, Vestweber D (Mar 1995). "The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor". Nature. 373 (6515): 615–20. Bibcode:1995Natur.373..615S. doi:10.1038/373615a0. PMID   7531823. S2CID   1602373.
7. "Entrez Gene: GLG1 golgi apparatus protein 1".

Further reading

• Burrus LW, Zuber ME, Lueddecke BA, Olwin BB (1992). "Identification of a cysteine-rich receptor for fibroblast growth factors". Mol. Cell. Biol. 12 (12): 5600–9. doi:10.1128/MCB.12.12.5600. PMC   360499 . PMID   1448090.
• Croul S, Mezitis SG, Stieber A, et al. (1990). "Immunocytochemical visualization of the Golgi apparatus in several species, including human, and tissues with an antiserum against MG-160, a sialoglycoprotein of rat Golgi apparatus". J. Histochem. Cytochem. 38 (7): 957–63. doi: 10.1177/38.7.2355176 . PMID   2355176.
• Mourelatos Z, Gonatas JO, Cinato E, Gonatas NK (1997). "Cloning and sequence analysis of the human MG160, a fibroblast growth factor and E-selectin binding membrane sialoglycoprotein of the Golgi apparatus". DNA Cell Biol. 15 (12): 1121–8. doi:10.1089/dna.1996.15.1121. PMID   8985126.
• Steegmaier M, Borges E, Berger J, et al. (1997). "The E-selectin-ligand ESL-1 is located in the Golgi as well as on microvilli on the cell surface". J. Cell Sci. 110 (6): 687–94. doi:10.1242/jcs.110.6.687. PMID   9099943.
• Olofsson A, Hellman U, Ten Dijke P, et al. (1997). "Latent transforming growth factor-beta complex in Chinese hamster ovary cells contains the multifunctional cysteine-rich fibroblast growth factor receptor, also termed E-selectin-ligand or MG-160". Biochem. J. 324 (Pt 2): 427–34. doi:10.1042/bj3240427. PMC   1218448 . PMID   9182700.
• Wild MK, Huang MC, Schulze-Horsel U, et al. (2001). "Affinity, kinetics, and thermodynamics of E-selectin binding to E-selectin ligand-1". J. Biol. Chem. 276 (34): 31602–12. doi: 10.1074/jbc.M104844200 . PMID   11404363.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Yamaguchi F, Morrison RS, Gonatas NK, et al. (2003). "Identification of MG-160, a FGF binding medial Golgi sialoglycoprotein, in brain tumors: an index of malignancy in astrocytomas". Int. J. Oncol. 22 (5): 1045–9. doi:10.3892/ijo.22.5.1045. PMID   12684670.
• Zhang H, Li XJ, Martin DB, Aebersold R (2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nat. Biotechnol. 21 (6): 660–6. doi:10.1038/nbt827. PMID   12754519. S2CID   581283.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID   14743216. S2CID   11683986.
• Ahn J, Febbraio M, Silverstein RL (2005). "A novel isoform of human Golgi complex-localized glycoprotein-1 (also known as E-selectin ligand-1, MG-160 and cysteine-rich fibroblast growth factor receptor) targets differential subcellular localization". J. Cell Sci. 118 (Pt 8): 1725–31. doi: 10.1242/jcs.02310 . PMID   15797922.