GPR89B

GPR89B
Identifiers
Aliases	GPR89B , GPHR, GPR89, GPR89C, SH120, UNQ192, G protein-coupled receptor 89B
External IDs	OMIM: 612806; MGI: 1914799; HomoloGene: 9475; GeneCards: GPR89B; OMA:GPR89B - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q21.2 Start 147,928,393 bp [1] End 147,993,592 bp [1]
Gene location (Mouse) Chr. Chromosome 3 (mouse) [2] Band 3|3 F2.1 Start 96,775,597 bp [2] End 96,812,662 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle duodenum corpus callosum Achilles tendon human kidney body of pancreas granulocyte cerebellar cortex cerebellar hemisphere right lobe of liver Top expressed in spermatocyte lacrimal gland jejunum otic vesicle ileum saccule intestinal epithelium interventricular septum epithelium of small intestine right lobe of liver More reference expression data BioGPS n/a
Gene ontology Molecular function voltage-gated anion channel activity signal transducer activity voltage-gated ion channel activity Cellular component integral component of membrane Golgi cisterna membrane Golgi-associated vesicle membrane Golgi membrane Golgi apparatus membrane Biological process protein transport positive regulation of I-kappaB kinase/NF-kappaB signaling regulation of ion transmembrane transport ion transport intracellular pH reduction signal transduction regulation of anion transmembrane transport transport ion transmembrane transport inorganic anion transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51463 67549 Ensembl ENSG00000188092 ENSMUSG00000028096 UniProt P0CG08 Q8BS95 RefSeq (mRNA) NM_001097616 NM_001350180 NM_001350181 NM_001350182 NM_001350183 NM_001350184 NM_016334 NM_026229 RefSeq (protein) NP_001091081 NP_001091082 NP_001337109 NP_001337110 NP_001337111 NP_001337112 NP_001337113 NP_057418 NP_001337109 NP_001337110 NP_001337111 NP_001337112 NP_001337113 NP_057418 NP_001091081 NP_001091082 NP_080505 Location (UCSC) Chr 1: 147.93 – 147.99 Mb Chr 3: 96.78 – 96.81 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Protein GPR89 is a protein that in humans is encoded by the GPR89B gene. ^{[5] [6]}

Related gene problems

• 1q21.1 deletion syndrome
• 1q21.1 duplication syndrome

References

1. GRCh38: Ensembl release 89: ENSG00000188092 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000028096 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC   310934 . PMID   11042152.
6. "Entrez Gene: GPR89A G protein-coupled receptor 89A".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC   310876 . PMID   10810093.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Matsuda A, Suzuki Y, Honda G, et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways". Oncogene. 22 (21): 3307–18. doi: 10.1038/sj.onc.1206406 . PMID   12761501.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.