Azadirachtin, a chemical compound belonging to the limonoid group, is a secondary metabolite present in neem seeds. It is a highly oxidized tetranortriterpenoid which boasts a plethora of oxygen-bearing functional groups, including an enol ether, acetal, hemiacetal, tetra-substituted epoxide and a variety of carboxylic esters.
Temperate rainforests are coniferous or broadleaf forests that occur in the temperate zone and receive heavy rain.
Total synthesis is the complete chemical synthesis of a complex molecule, often a natural product, from simple, commercially-available precursors. It usually refers to a process not involving the aid of biological processes, which distinguishes it from semisynthesis. Syntheses may sometimes conclude at a precursor with further known synthetic pathways to a target molecule, in which case it is known as a formal synthesis. Total synthesis target molecules can be natural products, medicinally-important active ingredients, known intermediates, or molecules of theoretical interest. Total synthesis targets can also be organometallic or inorganic, though these are rarely encountered. Total synthesis projects often require a wide diversity of reactions and reagents, and subsequently requires broad chemical knowledge and training to be successful.
Peter G. Schultz is an American chemist. He is the CEO and Professor of Chemistry at The Scripps Research Institute, the founder and former director of GNF, and the founding director of the California Institute for Biomedical Research (Calibr), established in 2012. In August 2014, Nature Biotechnology ranked Schultz the #1 top translational researcher in 2013.
World Community Grid (WCG) is an effort to create the world's largest public computing grid to tackle scientific research projects that benefit humanity. Launched on November 16, 2004, it was co-ordinated by IBM with client software currently available for Windows, Linux, macOS, and Android operating systems. In September 2021, it was announced that IBM transferred ownership to the Krembil Research Institute.
Medicine Man is a 1992 American adventure drama film directed by American action director John McTiernan. The film stars Sean Connery and Lorraine Bracco, and features an acclaimed score by veteran composer Jerry Goldsmith.
Benjamin Franklin Cravatt III is a professor in the Department of Chemistry at The Scripps Research Institute in La Jolla, California. Considered a co-inventor of activity based proteomics and a substantial contributor to research on the endocannabinoid system, he is a prominent figure in the nascent field of chemical biology. Cravatt was elected to the National Academy of Sciences in 2014, and the American Academy of Arts and Sciences in 2016. He is Gilula Chair of Chemical Biology, a Cope Scholar, and a Searle Scholar.
Galbulimima is a genus of flowering plants and the sole genus of the family Himantandraceae. Members of the family are found in the tropical zones of eastern Malaysia, the Moluccas, the Celebes, New Guinea, northern Australia and the Solomon Islands.
Tasmannia lanceolata, commonly known as Tasmanian pepperberry or mountain pepper, is a shrub native to woodlands and cool temperate rainforest of south-eastern Australia. The shrub varies from 2 to 10 m high. The aromatic leaves are lanceolate to narrow-elliptic or oblanceolate, 4–12 cm long, and 0.7–2.0 cm wide, with a distinctly pale undersurface. Stems are quite red in colour. The small cream or white flowers appear in summer and are followed by black, globose, two-lobed berries 5–8 mm wide, which appear in autumn. There are separate male and female plants.
Intsia bijuga, commonly known as Borneo teak, Johnstone River teak, Kwila, Moluccan ironwood, Pacific teak, scrub mahogany and vesi, is a species of flowering tree in the family Fabaceae, native to the Indo-Pacific. It ranges from Tanzania and Madagascar east through India and Queensland, Australia, Papua New Guinea to the Pacific islands of Fiji and Samoa.It grows to around 50 metres tall with a highly buttressed trunk. It inhabits mangrove forests. Intsia bijuga differ from Intsia palembanica in the number of leaflets that make up their compound leaves.
Buckinghamia is a genus of only two known species of trees, belonging to the plant family Proteaceae. They are endemic to the rainforests of the wet tropics region of north eastern Queensland, Australia. The ivory curl flower, B. celsissima, is the well known, popular and widely cultivated species in gardens and parks, in eastern and southern mainland Australia, and additionally as street trees north from about Brisbane. The second species, B. ferruginiflora, was only recently described in 1988.
Samuel J. Danishefsky is an American chemist working as a professor at both Columbia University and the Memorial Sloan-Kettering Cancer Center in New York City.
MPP+ (1-methyl-4-phenylpyridinium) is a positively charged organic molecule with the chemical formula C12H12N+. It is a neurotoxin that acts by interfering with oxidative phosphorylation in mitochondria by inhibiting complex I, leading to the depletion of ATP and eventual cell death.
In organic chemistry, an intramolecular Diels-Alder cycloaddition is a Diels–Alder reaction in which the diene and a dienophile are both part of the same molecule. The reaction leads to the formation of the same cyclohexene-like structure as usual for a Diels–Alder reaction, but as part of a more complex fused or bridged cyclic ring system.
Endiandric acid C, isolated from the tree Endiandra introrsa, is a well characterized chemical compound. Endiadric acid C is reported to have better antibiotic activity than ampicillin.
Carnarvonia is a flowering plant genus of a single species, commonly named red oak or red silky oak and constituting part of the plant family Proteaceae. The single species named Carnarvonia araliifolia grows to large trees of 30 m (100 ft) or more. They grow naturally only (endemic) to the Wet Tropics rainforests region of north-eastern Queensland, Australia. The species has two described varieties, C. araliifolia var. araliifolia and C. araliifolia var. montana, and the common names are used for both.
Lasjia is a genus of five species of trees of the family Proteaceae. Three species grow naturally in northeastern Queensland, Australia and two species in Sulawesi, Indonesia. Descriptively they are the tropical or northern macadamia trees group. Lasjia species characteristically branched compound inflorescences differentiate them from the Macadamia species, of Australia, which have characteristically unbranched compound inflorescences and only grow naturally about 1,000 km (620 mi) further to the south, in southern and central eastern Queensland and in northeastern New South Wales.
Phil S. Baran is a Professor in the Department of Chemistry at the Scripps Research Institute and Member of the Skaggs Institute for Chemical Biology. Baran has authored over 130 published scientific articles. He has several patents. His work is focused on synthesizing complex organic compounds, the development of new reactions, and the development of new reagents.
Lomatia polymorpha, commonly known as mountain guitar plant, is a shrub or small tree of the family Proteaceae which is endemic to Tasmania. It is a shrub or small tree with linear leaves, and white, cream-coloured or greenish flowers. It is common throughout its range which is approximately complementary to that of L. tinctoria in Tasmania.
Intsia palembanica is a species of flowering plants in the family Fabaceae. The plant common names include Borneo teak, Malacca teak, merbau and Moluccan ironwood where it is native to tropical rainforests in Southeast Asia and the islands of the southwest Pacific. Intsia palembanica differ from Intsia bijuga in the number of leaflets that make up their compound leaves.
