Geodin

Geodin

Names
IUPAC name Methyl (2R)-5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate [1]
Other names Estin Erdin methyl ester
Identifiers
CAS Number	427-63-4  Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:150867
ChEMBL	ChEMBL1956530
ChemSpider	8062819
PubChem CID	9887146
UNII	4293R7B06X
CompTox Dashboard (EPA)	DTXSID80962632
InChI InChI=1S/C17H12Cl2O7/c1-6-11(18)13(21)10-14(12(6)19)26-17(15(10)22)8(16(23)25-3)4-7(20)5-9(17)24-2/h4-5,21H,1-3H3/t17-/m1/s1 Key: LUBKKVGXMXTXOZ-QGZVFWFLSA-N
SMILES CC1=C(C(=C2C(=C1Cl)O[C@]3(C2=O)C(=CC(=O)C=C3OC)C(=O)OC)O)Cl
Properties
Chemical formula	C17H12Cl2O7
Molar mass	399.18 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Geodin is an antibiotic against Gram-positive bacteria with the molecular formula C₁₇H₈Cl₂O₇. ^{[1] [2]} Geodin is produced by the fungus Aspergillus terreus . ^{[3] [4]}

References

1. "Geodin". Pubchem.ncbi.NLM.nih.gov.
2. Korzybski, Tadeusz; Kowszyk-Gindifer, Zuzanna; Kurylowicz, Wlodzimierz (3 September 2013). Antibiotics: Origin, Nature and Properties. Elsevier. p. 1291. ISBN   978-1-4832-2304-9.
3. Rønnest, Mads H.; Nielsen, Morten T.; Leber, Blanka; Mortensen, Uffe H.; Krämer, Alwin; Clausen, Mads H.; Larsen, Thomas O.; Harris, Pernille (15 March 2011). "(+)-Geodin from Aspergillus terreus". Acta Crystallographica Section C Crystal Structure Communications. 67 (3): o125 –o128. Bibcode:2011AcCrC..67O.125R. doi: 10.1107/S0108270111005816 . PMID   21368412.
4. Gottlieb, David; Shaw, Paul D. (14 December 2013). Biosynthesis. Springer. p. 96. ISBN   978-3-662-38441-1.

Further reading

• Vaidyanathan, Seetharaman; Harrigan, George G.; Goodacre, Royston (20 March 2006). Metabolome Analyses:: Strategies for Systems Biology. Springer Science & Business Media. p. 377. ISBN   978-0-387-25240-7.
• Comprehensive Natural Products III. Elsevier. 22 July 2020. p. 299. ISBN   978-0-08-102691-5.