Germacrone

Germacrone

Names
Preferred IUPAC name (3E,7E)-3,7-Dimethyl-10-(propan-2-ylidene)cyclodeca-3,7-dien-1-one
Identifiers
CAS Number	6902-91-6
3D model (JSmol)	Interactive image
ChEBI	CHEBI:80830
ChemSpider	4940991
EC Number	834-535-3
KEGG	C16966
PubChem CID	6436348
UNII	E2WQ6N4FBP  Y
InChI InChI=1S/C15H22O/c1-11(2)14-9-8-12(3)6-5-7-13(4)10-15(14)16/h7-8H,5-6,9-10H2,1-4H3/b12-8+,13-7+ Key: CAULGCQHVOVVRN-SWZPTJTJSA-N
SMILES C/C/1=C\CC(=C(C)C)C(=O)C/C(=C/CC1)/C
Properties
Chemical formula	C15H22O
Molar mass	218.340 g·mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards	flammable
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Germacrone is a sesquiterpene which has been isolated via distillation from the plant species Geranium macrorrhizum . ^[1] It has shown antiviral properties in an animal model of influenza infection. ^[2]

References

1. Radulović, Niko S.; Dekić, Milan S.; Stojanović-Radić, Zorica Z.; Zoranić, Suad K. (2010). "Geranium macrorrhizum L. (Geraniaceae) essential oil: a potent agent against Bacillus subtilis". Chemistry & Biodiversity. 7 (11): 2783–800. doi:10.1002/cbdv.201000100. PMID   21072778. S2CID   7366166.
2. Liao, Q; Qian, Z; Liu, R; An, L; Chen, X (2013). "Germacrone inhibits early stages of influenza virus infection". Antiviral Research. 100 (3): 578–88. doi:10.1016/j.antiviral.2013.09.021. PMID   24095670.