Gloria M. Coruzzi

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Gloria M. Coruzzi
GloriaCoruzzi wik .jpg
Born (1954-06-28) June 28, 1954 (age 69)
New York City, US
Alma mater Hunter College High School

Fordham University (B.S.)

NYU School of Medicine (Ph.D)
Known for Gene regulatory networks affecting nitrogen use efficiency
Awards National Academy of Sciences (Member)
New York Botanical Garden (Distinguished Counselor)
Scientific career
FieldsPlant Systems Biology
Institutions Rockefeller University (1980-1991)
New York University (1992-present)
Website coruzzilab.bio.nyu.edu

Gloria M. Coruzzi (born June 28, 1954) is an American molecular biologist specializing in plant systems biology and evolutionary genomics.

Contents

Education and career

As Carroll & Milton Petrie Professor of Biology at New York University’s Center for Genomics and Systems Biology, Coruzzi studies gene regulatory networks controlling nitrogen use efficiency (NUE) and root nutrient foraging in the model plant Arabidopsis . She also examines phylogenomic approaches across higher plant species to identify genes associated with the evolution of key plant traits such as seeds. [1] This research resides in Pasteur's quadrant as a scientific investigation that is ultimately meant to be beneficial to society. [2]

Coruzzi has established 10 patents in the study of gene networks affecting nitrogen use efficiency. Her laboratory collaborated in the development of the software platform VirtualPlant. [3]

As an investigator on the National Science Foundation (NSF) Plant Genome project, she helped generate the largest genome-scale phylogeny of the seed plants, which allows researchers to explore the genomic underpinnings of plant diversity. [1] [4]

Coruzzi is from New York. She went to Hunter College High School (class of 1972) and took her Bachelor of Science in biology from Fordham University in 1976. [5] For studies of the genetic code in yeast mitochondrial DNA. [6] She earned her PhD in molecular and cell biology at NYU School of Medicine in 1979. In a post-doctoral National Institutes of Health (NIH) fellowship, she applied molecular approaches to plants that contributed to the cloning of one of the first plant nuclear genes. [7] As an associate professor at Rockefeller University, Coruzzi identified key genes controlling the assimilation of inorganic nitrogen into key amino acids used for nitrogen transport in plants. [8] [9]

Coruzzi took a position as a professor at NYU in 1993. Her lab has constructed the first integrated genomic network used to discover and validate nitrogen regulation of the circadian clock in plants. [10] It predicted the function of gene network states under untested conditions. [11]

She is a member of the Editorial Board for PNAS . [12]

Coruzzi has authored and coauthored over 200 research papers and served as chair of the Department of Biology at NYU from 2003 to 2011. Her research is funded by the National Institutes of Health, NSF 2010 Project, NSF Plant Genome Project, the NSF Database and Information Project, and United States Department of Energy. [13]

Awards and honors

Coruzzi was named a Fellow of the American Association for the Advancement of Science in 2005, a Fellow of the American Society of Plant Biology in 2010, a Fellow of the Agropolis Foundation in 2012.

Coruzzi was awarded Stephen Hales Prize in 2016 for her pioneering work in exploring plant systems biology and the first integrated view of mechanisms controlling the assimilation and use of nitrogen. [14]

Coruzzi was appointed Distinguished Counselor at New York Botanical Garden in 2017 for her professional accomplishments in the field of plant science. [15]

She was elected to the National Academy of Sciences in 2019. [16] [17]

Coruzzi has been recognized as a Pioneer Member of the American Society of Plant Biologists. [18]

Advisory boards

1994–1997, North American Arabidopsis Steering Committee [13]
1996–1999, International Society of Plant Molecular Biology, Board of Directors [13]
1996–2000, International Society of Plant Molecular Biology, Board Member [13]
2008–Present, New York Botanical Garden, Member of the Corporation [13]
2012–2015, Donald Danforth Plant Science Center, Scientific Advisory Board [13]
2012–2017, International Arabidopsis Informatics Consortium, Scientific Board [13]
2012–2017, The Arabidopsis Information Portal Scientific Advisory Board [13]
2015–2018, Department of Energy (DOE) Joint Genome Institute Plant Program User Advisory Committee [19]
2019–Present, DOE Joint Genome Institute Scientific Advisory Committee [20]

Related Research Articles

<span class="mw-page-title-main">Genome</span> All genetic material of an organism

In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA. The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences, and often a substantial fraction of junk DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome.

<span class="mw-page-title-main">Sequence homology</span> Shared ancestry between DNA, RNA or protein sequences

Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life. Two segments of DNA can have shared ancestry because of three phenomena: either a speciation event (orthologs), or a duplication event (paralogs), or else a horizontal gene transfer event (xenologs).

The Max Planck Institute of Molecular Plant Physiology is a German research institute for molecular plant physiology, based in the Golm district of Potsdam, Brandenburg. Founded on 1 January 1994, the MPIMP focuses on the study of the dynamics of plant metabolism and how that relates to the entire plant system. The institution is one of the 80 institutes in the Max Planck Society (Max-Planck-Gesellschaft).

Evolutionary developmental biology (evo-devo) is the study of developmental programs and patterns from an evolutionary perspective. It seeks to understand the various influences shaping the form and nature of life on the planet. Evo-devo arose as a separate branch of science rather recently. An early sign of this occurred in 1999.

<span class="mw-page-title-main">Plant evolution</span> Subset of evolutionary phenomena that concern plants

Plant evolution is the subset of evolutionary phenomena that concern plants. Evolutionary phenomena are characteristics of populations that are described by averages, medians, distributions, and other statistical methods. This distinguishes plant evolution from plant development, a branch of developmental biology which concerns the changes that individuals go through in their lives. The study of plant evolution attempts to explain how the present diversity of plants arose over geologic time. It includes the study of genetic change and the consequent variation that often results in speciation, one of the most important types of radiation into taxonomic groups called clades. A description of radiation is called a phylogeny and is often represented by type of diagram called a phylogenetic tree.

<span class="mw-page-title-main">Ralf Reski</span> Plant biologist

Ralf Reski is a German professor of plant biotechnology and former dean of the Faculty of Biology of the University of Freiburg. He is also affiliated to the French École supérieure de biotechnologie Strasbourg (ESBS) and Senior Fellow at the Freiburg Institute for Advanced Studies.

Michael D. Purugganan is a Filipino-American biologist and former journalist. He is the Silver Professor of Biology and the former Dean of Science of New York University (NYU). Purugganan is also an affiliated faculty member of NYU Abu Dhabi (NYUAD) and the NYU Institute for the Study of the Ancient World (ISAW), and since 2022, has been the director of 19 Washington Square North, the academic space of NYUAD in New York City. He was the former director of the NYU Center for Genomics and Systems Biology in New York (2010-2012) and Abu Dhabi (2012-2017).

Julia Bailey-Serres is professor of genetics, director of the Center for Plant Cell Biology, and a member of the Institute for Integrative Genome Biology at the University of California, Riverside. Her accomplishments include the pioneering of methods for profiling the "translatomes" of discrete cell-types of plants and identification of a homeostatic sensor of oxygen deprivation in plants.

Steve A. Kay is a British-born chronobiologist who mainly works in the United States. Dr. Kay has pioneered methods to monitor daily gene expression in real time and characterized circadian gene expression in plants, flies and mammals. In 2014, Steve Kay celebrated 25 years of successful chronobiology research at the Kaylab 25 Symposium, joined by over one hundred researchers with whom he had collaborated with or mentored. Dr. Kay, a member of the National Academy of Sciences, U.S.A., briefly served as president of The Scripps Research Institute. and is currently a professor at the University of Southern California. He also served on the Life Sciences jury for the Infosys Prize in 2011.

Karen Koch is a plant biologist in the horticultural science department in the University of Florida. She is a professor in the Plant Molecular and Cellular Biology (PMCB) Program, Horticultural Sciences Department, and Genetics Institute at University of Florida.

Robert L. Last is a plant biochemical genomicist who studies metabolic processes that protect plants from the environment and produce products important for animal and human nutrition. His research has covered (1) production and breakdown of essential amino acids, (2) the synthesis and protective roles of Vitamin C and Vitamin E (tocopherols) as well as identification of mechanisms that protect photosystem II from damage, and (3) synthesis and biological functions of plant protective specialized metabolites. Four central questions are: (i) how are leaf and seed amino acids levels regulated, (ii.) what mechanisms protect and repair photosystem II from stress-induced damage, (iii.) how do plants produce protective metabolites in their glandular secreting trichomes (iv.) and what are the evolutionary mechanisms that contribute to the tremendous diversity of specialized metabolites that protect plants from insects and pathogens and are used as therapeutic agents.

Arabidopsis thaliana is a first class model organism and the single most important species for fundamental research in plant molecular genetics.

<span class="mw-page-title-main">Sarah Wyatt</span> American molecular biologist

Sarah Wyatt is an American, plant molecular biologist. She is a Professor in the Department of Environmental and Plant Biology at Ohio University, as well as director of the Ohio University Interdisciplinary Graduate Program in Molecular and Cellular Biology. Wyatt's research interests include molecular biology, genomics, and signaling events. She is considered one of the world's experts on gravitational signaling in plants, and some of her recent research includes an experiment on board the International Space Station (ISS).

Nikos Kyrpides is a Greek-American bioscientist who has worked on the origins of life, information processing, bioinformatics, microbiology, metagenomics and microbiome data science. He is a senior staff scientist at the Berkeley National Laboratory, head of the Prokaryote Super Program and leads the Microbiome Data Science program at the US Department of Energy Joint Genome Institute.

Dr. Beronda Montgomery is a writer, science communicator, and researcher. In 2022, she moved to Grinnell College as professor of biology and vice president for academic affairs and dean of the college. Prior to Grinnell, Montgomery served as Michigan State University Foundation Professor in the Departments of Biochemistry & Molecular Biology and of Microbiology & Molecular Genetics. She was also a member of the MSU-DOE Plant Research Laboratory. Her research group investigates how photosynthetic organisms adapt to changes in their environment. Her scholarship extends beyond biology and into studying mentorship and faculty development to develop evidence-based strategies to foster equity and inclusion in academia. Together with Tanisha Williams and other members of the Black Botanists Week organizing committee, Montgomery co-founded and co-organizes Black Botanists Week.

Michel Delseny is director of research emeritus at the CNRS and a member of the French Academy of sciences.

The MSU-DOE Plant Research Laboratory (PRL), commonly referred to as Plant Research Lab, is a research institute funded to a large extent by the U.S. Department of Energy Office of Science and located at Michigan State University (MSU) in East Lansing, Michigan. The Plant Research Lab was founded in 1965, and it currently includes twelve laboratories that conduct collaborative basic research into the biology of diverse photosynthetic organisms, including plants, bacteria, and algae, in addition to developing new technologies towards addressing energy and food challenges.

<span class="mw-page-title-main">Wojciech Karlowski</span> Polish biologist specializing in molecular biology and bioinformatics

Wojciech Maciej Karlowski is a Polish biologist specializing in molecular biology and bioinformatics, and a full professor in biological sciences. He is Head of the Department of Computational Biology at the Faculty of Biology at the Adam Mickiewicz University in Poznan. His major scientific interests include identification of non-coding RNAs, genomics, high-throughput analyses, and functional annotation of biological sequences.

Christoph Benning is a German–American plant biologist. He is an MSU Foundation Professor and University Distinguished Professor at Michigan State University. Benning's research into lipid metabolism in plants, algae and photosynthetic bacteria, led him to be named Editor-in-Chief of The Plant Journal in October 2008.

References

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  9. Tsai, F. Y. and G. M. Coruzzi. (1990). Dark-induced and organ-specific expression of two asparagine synthetase genes in Pisum sativum. EMBO J. 9: 323-32.
  10. Gutiérrez, R., et al. (2008). Systems approach identifies an organic nitrogen-responsive gene network that is regulated by the master clock control gene CCA1. Proc. Natl Acad Sci USA 105, 4939-44.
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  12. "Editorial Board | PNAS".
  13. 1 2 3 4 5 6 7 8 "Gloria M. Coruzzi - New York University - Faculty". www.nyu.edu. Retrieved 2019-05-03.
  14. "Stephen Hales Prize". www.aspb.org. Retrieved 2019-05-05.
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