HEBP1

Last updated
HEBP1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases HEBP1 , HBP, HEBP, heme binding protein 1
External IDs OMIM: 605826; MGI: 1333880; HomoloGene: 8407; GeneCards: HEBP1; OMA:HEBP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015987

NM_013546

RefSeq (protein)

NP_057071

NP_038574

Location (UCSC) Chr 12: 12.97 – 13 Mb Chr 6: 135.11 – 135.18 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Heme binding protein 1 is a protein that in humans is encoded by the HEBP1 gene. [5]

Contents

Function

The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. [5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000013583 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042770 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: Heme binding protein 1".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.