Hibifolin

Last updated
Hibifolin
Hibifolin.svg
Names
IUPAC name
3,3′,4′,5,7-Pentahydroxy-4-oxoflav-2-en-8-yl β-D-glucopyranosiduronic acid
Systematic IUPAC name
(2S,3S,4S,5R,6S)-6-{[2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4-oxo-4H-1-benzopyran-8-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
Identifiers
3D model (JSmol)
ChemSpider
PubChem CID
  • InChI=1S/C21H18O14/c22-6-2-1-5(3-7(6)23)16-13(28)11(26)10-8(24)4-9(25)17(18(10)33-16)34-21-15(30)12(27)14(29)19(35-21)20(31)32/h1-4,12,14-15,19,21-25,27-30H,(H,31,32)/t12-,14-,15+,19-,21+/m0/s1
    Key: KHVMAMXQPVHXTJ-ORYXKJSJSA-N
  • InChI=1/C21H18O14/c22-6-2-1-5(3-7(6)23)16-13(28)11(26)10-8(24)4-9(25)17(18(10)33-16)34-21-15(30)12(27)14(29)19(35-21)20(31)32/h1-4,12,14-15,19,21-25,27-30H,(H,31,32)/t12-,14-,15+,19-,21+/m0/s1
    Key: KHVMAMXQPVHXTJ-ORYXKJSJBB
  • C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)O)O)O
Properties
C21H18O14
Molar mass 494.36 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Hibifolin is a flavonol glycoside that prevents beta-amyloid-induced neurotoxicity in vitro . [1]

References

  1. ↑ Zhu, JT; Choi, RC; Xie, HQ; Zheng, KY; Guo, AJ; Bi, CW; Lau, DT; Li, J; Dong, TT; Lau, BW; Chen, JJ; Tsim, KW (2009). "Hibifolin, a flavonol glycoside, prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons". Neuroscience Letters. 461 (2): 172–6. doi:10.1016/j.neulet.2009.06.010. PMID   19539722. S2CID   32342156.


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