IMPG1

IMPG1
Identifiers
Aliases	IMPG1 , GP147, IPM150, SPACR, VMD4, interphotoreceptor matrix proteoglycan 1, RP91
External IDs	OMIM: 602870 MGI: 1926876 HomoloGene: 1201 GeneCards: IMPG1
Gene location (Human)
Chr.	Chromosome 6 (human)
End	76,072,678 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	80,347,534 bp
RNA expression pattern
	Top expressed in
	nucleus accumbens; ; secondary oocyte; ; caudate nucleus; ; putamen; ; Brodmann area 9; ; right lung; ; prefrontal cortex; ; cingulate gyrus; ; body of pancreas; ; minor salivary gland;
	Top expressed in
	retinal pigment epithelium; ; semi-lunar valve; ; left ventricle; ; aortic valve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	extracellular matrix structural constituent ;
Cellular component	extracellular region ; extracellular matrix ;
Biological process	visual perception ;
	Sources:Amigo / QuickGO
Orthologs
	3617
	63859
	ENSG00000112706
	ENSMUSG00000032343
	Q17R60
	Q8R1W8
	NM_001563 ; NM_001282368
	NM_022016
	NP_001269297 ; NP_001554
	NP_071299
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Interphotoreceptor matrix proteoglycan 1 is a protein that in humans is encoded by the IMPG1 gene.^[5]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000112706 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032343 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: IMPG1 interphotoreceptor matrix proteoglycan 1".

Felbor U, Gehrig A, Sauer CG, et al. (1998). "Genomic organization and chromosomal localization of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene: a candidate for 6q-linked retinopathies". Cytogenet. Cell Genet. 81 (1): 12–7. doi:10.1159/000015001. PMID 9691169. S2CID 46766267.
Gehrig A, Felbor U, Kelsell RE, et al. (1998). "Assessment of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene localised to 6q13-q15 in autosomal dominant Stargardt-like disease (ADSTGD), progressive bifocal chorioretinal atrophy (PBCRA), and North Carolina macular dystrophy (MCDR1)". J. Med. Genet. 35 (8): 641–5. doi:10.1136/jmg.35.8.641. PMC 1051388 . PMID 9719369.
Acharya S, Rayborn ME, Hollyfield JG (1998). "Characterization of SPACR, a sialoprotein associated with cones and rods present in the interphotoreceptor matrix of the human retina: immunological and lectin binding analysis". Glycobiology. 8 (10): 997–1006. doi: 10.1093/glycob/8.10.997 . PMID 9719680.
Acharya S, Rodriguez IR, Moreira EF, et al. (1998). "SPACR, a novel interphotoreceptor matrix glycoprotein in human retina that interacts with hyaluronan". J. Biol. Chem. 273 (47): 31599–606. doi: 10.1074/jbc.273.47.31599 . PMID 9813076.
Kuehn MH, Hageman GS (2000). "Expression and characterization of the IPM 150 gene (IMPG1) product, a novel human photoreceptor cell-associated chondroitin-sulfate proteoglycan". Matrix Biol. 18 (5): 509–18. doi:10.1016/S0945-053X(99)00043-8. PMID 10601738.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi: 10.1038/nature02055 . PMID 14574404.
van Lith-Verhoeven JJ, Hoyng CB, van den Helm B, et al. (2004). "The benign concentric annular macular dystrophy locus maps to 6p12.3-q16". Invest. Ophthalmol. Vis. Sci. 45 (1): 30–5. doi: 10.1167/iovs.03-0392 . PMID 14691150.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Abd El-Aziz MM, El-Ashry MF, Barragan I, et al. (2006). "Molecular genetic analysis of two functional candidate genes in the autosomal recessive retinitis pigmentosa, RP25, locus". Curr. Eye Res. 30 (12): 1081–7. doi:10.1080/02713680500351039. PMID 16354621. S2CID 26204316.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000112706 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032343 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: IMPG1 interphotoreceptor matrix proteoglycan 1".

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IMPG1

Related Research Articles

References

Further reading