INSL5

INSL5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2K1V, 2KBC
Identifiers
Aliases	INSL5 , PRO182, UNQ156, insulin like 5
External IDs	OMIM: 606413 MGI: 1346085 HomoloGene: 48350 GeneCards: INSL5
Gene location (Human)
Chr.	Chromosome 1 (human)
End	66,801,276 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	102,884,039 bp
RNA expression pattern
	Top expressed in
	rectum; ; right uterine tube; ; hypothalamus; ; Brodmann area 9; ; nucleus accumbens; ; hippocampus proper; ; muscle tissue; ; cingulate gyrus; ; caudate nucleus; ; amygdala;
	Top expressed in
	left colon; ; thymus; ; spermatid; ; inner nuclear layer; ; enteric nervous system; ; outer nuclear layer; ; superior frontal gyrus; ; cervix; ; submandibular gland; ; mirror;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	hormone activity ; G protein-coupled receptor binding ;
Cellular component	extracellular region ; cellular component ;
Biological process	positive regulation of feeding behavior ; regulation of signaling receptor activity ; G protein-coupled receptor signaling pathway ; biological process ;
	Sources:Amigo / QuickGO
Orthologs
	10022
	23919
	ENSG00000172410
	ENSMUSG00000066090
	Q9Y5Q6
	Q9WUG6
	NM_005478
	NM_001290648 ; NM_011831
	NP_005469
	NP_001277577 ; NP_035961
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated February 02, 2023

Insulin-like peptide 5 (INSL5) is a protein that in humans is encoded by the INSL5 gene.^[5]^[6]

Function

The protein encoded by this gene contains a classical signature of the insulin superfamily and is highly similar to relaxin 3 (RLN3/INSL7).^[6]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000172410 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000066090 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Conklin D, Lofton-Day CE, Haldeman BA, Ching A, Whitmore TE, Lok S, Jaspers S (August 1999). "Identification of INSL5, a new member of the insulin superfamily". Genomics. 60 (1): 50–6. doi:10.1006/geno.1999.5899. PMID 10458910.
1 2 "Entrez Gene: INSL5 insulin-like 5".

External links

INSL5 human gene location in the UCSC Genome Browser .
INSL5 human gene details in the UCSC Genome Browser .
Overview of all the structural information available in the PDB for UniProt : Q9Y5Q6 (Human Insulin-like peptide INSL5) at the PDBe-KB .

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000172410 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000066090 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10458910-5] Conklin D, Lofton-Day CE, Haldeman BA, Ching A, Whitmore TE, Lok S, Jaspers S (August 1999). "Identification of INSL5, a new member of the insulin superfamily". Genomics. 60 (1): 50–6. doi:10.1006/geno.1999.5899. PMID 10458910.

[entrez-6] 1 2 "Entrez Gene: INSL5 insulin-like 5".

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INSL5

Contents

Function

Related Research Articles

References

Further reading

External links