INTS12 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | INTS12 , INT12, PHF22, SBBI22, integrator complex subunit 12 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 611355; MGI: 1919043; HomoloGene: 32474; GeneCards: INTS12; OMA:INTS12 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Integrator complex subunit 12 (Int12) also known as PHD finger protein 22 (PHF22) is a protein that in humans is encoded by the INTS12 gene. [4]
INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2) [4] [5]
Cyclin-C is a protein that in humans is encoded by the CCNC gene.
Poly(A) polymerase alpha is an enzyme that in humans is encoded by the PAPOLA gene.
Cleavage and polyadenylation specificity factor subunit 4 is a protein that in humans is encoded by the CPSF4 gene.
Mediator of RNA polymerase II transcription subunit 31 is a protein in humans encoded by the MED31 gene. It represents subunit Med31 of the Mediator complex. The family contains the Saccharomyces cerevisiae SOH1 homologues. SOH1 is responsible for the repression of temperature sensitive growth of the HPR1 mutant and has been found to be a component of the RNA polymerase II transcription complex. SOH1 not only interacts with factors involved in DNA repair, but transcription as well. Thus, the SOH1 protein may serve to couple these two processes.
Mediator of RNA polymerase II transcription subunit 7 is an enzyme that in humans is encoded by the MED7 gene.
Integrator complex subunit 6 is a protein that in humans is encoded by the INTS6 gene.
DNA-directed RNA polymerase I subunit RPA1 is an enzyme that in humans is encoded by the POLR1A gene.
DNA-directed RNA polymerase III subunit RPC10 is an enzyme that in humans is encoded by the POLR3K gene.
Integrator complex subunit 11 is a protein that in humans is encoded by the CPSF3L gene.
snRNA-activating protein complex subunit 1 is a protein that in humans is encoded by the SNAPC1 gene.
Mediator of RNA polymerase II transcription subunit 27 is an enzyme that in humans is encoded by the MED27 gene. It forms part of the Mediator complex.
Transcription factor IIIB 50 kDa subunit (TFIIIB50) also known as b-related factor 2 (BRF-2) is a protein that in humans is encoded by the BRF2 gene.
DNA-directed RNA polymerase III subunit RPC4 is an enzyme that in humans is encoded by the POLR3D gene.
Mediator of RNA polymerase II transcription subunit 26 is an enzyme that in humans is encoded by the MED26 gene. It forms part of the Mediator complex.
Integrator complex subunit 9 is a protein that in Humans is encoded by the INTS9 gene.
Integrator complex subunit 3 is a protein that in humans is encoded by the INTS3 gene.
Integrator complex subunit 7 is a protein that in humans is encoded by the INTS7 gene.
Integrator complex subunit 8 is a protein that in humans is encoded by the INTS8 gene.
snRNA-activating protein complex subunit 5 is a protein that in humans is encoded by the SNAPC5 gene.
Integrator complex subunit 1 is a protein that in humans is encoded by the INTS1 gene.