Imidocarb

Imidocarb

Names
Preferred IUPAC name N,N′-Bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]urea
Other names Imizocarb; Imizol; Diamidine
Identifiers
CAS Number	27885-92-3  Y
3D model (JSmol)	Interactive image
ChemSpider	20102
ECHA InfoCard	100.044.268
PubChem CID	21389
UNII	8USS3K0VDH
CompTox Dashboard (EPA)	DTXSID0048345
InChI InChI=1S/C19H20N6O/c26-19(24-15-5-1-3-13(11-15)17-20-7-8-21-17)25-16-6-2-4-14(12-16)18-22-9-10-23-18/h1-6,11-12H,7-10H2,(H,20,21)(H,22,23)(H2,24,25,26) Key: SCEVFJUWLLRELN-UHFFFAOYSA-N InChI=1/C19H20N6O/c26-19(24-15-5-1-3-13(11-15)17-20-7-8-21-17)25-16-6-2-4-14(12-16)18-22-9-10-23-18/h1-6,11-12H,7-10H2,(H,20,21)(H,22,23)(H2,24,25,26) Key: SCEVFJUWLLRELN-UHFFFAOYAD
SMILES O=C(Nc2cc(C/1=N/CCN\1)ccc2)Nc3cccc(c3)/C4=N/CCN4
Properties
Chemical formula	C19H20N6O
Molar mass	348.410 g·mol−1
Pharmacology
ATCvet code	QP51EX01 ( WHO )
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia (babesiosis) and other parasites. ^{[1] [2] [3]}

Mechanism of action

Imidocarb is anticholinergic; it inhibits acetylcholinesterase. ^{[4] [5]}

References

1. Hashemi-Fesharki, R (1977). "Studies on imidocarb dihydrochloride in experimental Babesia ovis infection in splenectomized lambs". The British Veterinary Journal. 133 (6): 609–14. doi:10.1016/S0007-1935(17)33941-6. PMID   608109.
2. Hashemi-Fesharki, R (1975). "Studies on imidocarb dihydrochloride in experimental Babesia bigemina infection in calves". The British Veterinary Journal. 131 (6): 666–72. doi:10.1016/S0007-1935(17)35138-2. PMID   1212605.
3. Kuttler, KL (1980). "Pharmacotherapeutics of drugs used in treatment of anaplasmosis and babesiosis". Journal of the American Veterinary Medical Association. 176 (10 Spec No): 1103–8. doi:10.2460/javma.1980.176.10.1103. PMID   7216881.
4. "Imidocarb". DrugBank . Retrieved November 23, 2024.
5. Papich, Mark G. (2016). Saunders Handbook of Veterinary Drugs (4th ed.). Elsevier. pp. 391–392. doi:10.1016/B978-0-323-24485-5.00304-1. ISBN   978-0-323-24485-5.