JKAMP

JKAMP
Identifiers
Aliases	JKAMP , C14orf100, HSPC213, HSPC327, JAMP, CDA06, JNK1/MAPK8-associated membrane protein, C24orf100, JNK1/MAPK8 associated membrane protein
External IDs	OMIM: 611176 MGI: 1915057 HomoloGene: 9524 GeneCards: JKAMP
Gene location (Human)
Chr.	Chromosome 14 (human)
End	59,505,410 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	72,148,235 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; tibia; ; monocyte; ; retinal pigment epithelium; ; pancreatic epithelial cell; ; parietal pleura; ; bronchial epithelial cell; ; rectum; ; gallbladder; ; smooth muscle tissue;
	Top expressed in
	facial motor nucleus; ; retinal pigment epithelium; ; ciliary body; ; iris; ; anterior horn of spinal cord; ; substantia nigra; ; external carotid artery; ; internal carotid artery; ; medullary collecting duct; ; arcuate nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	ubiquitin protein ligase binding ;
Cellular component	integral component of membrane ; endoplasmic reticulum membrane ; endoplasmic reticulum ; membrane ;
Biological process	response to unfolded protein ; ubiquitin-dependent ERAD pathway ;
	Sources:Amigo / QuickGO
Orthologs
	51528
	104771
	ENSG00000050130
	ENSMUSG00000005078
	Q9P055
	Q8BI36
NM_001098625 ; NM_001284201 ; NM_001284202 ; NM_001284203 ; NM_001284204 ;
	NM_016475
	NM_001205067 ; NM_024205
NP_001092095 ; NP_001271130 ; NP_001271131 ; NP_001271132 ; NP_001271133 ;
	NP_057559 ; NP_001271130.1
	NP_001191996 ; NP_077167
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 17, 2022

JNK1-associated membrane protein is a protein that in humans is encoded by the JKAMP gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000050130 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000005078 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Kadoya T, Khurana A, Tcherpakov M, Bromberg KD, Didier C, Broday L, Asahara T, Bhoumik A, Ronai Z (Sep 2005). "JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity". Mol Cell Biol. 25 (19): 8619–30. doi:10.1128/MCB.25.19.8619-8630.2005. PMC 1265750 . PMID 16166642.
↑ Tcherpakov M, Delaunay A, Toth J, Kadoya T, Petroski MD, Ronai ZA (Apr 2009). "Regulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP)". J Biol Chem. 284 (18): 12099–109. doi: 10.1074/jbc.M808222200 . PMC 2673279 . PMID 19269966.
↑ "Entrez Gene: C14orf100 chromosome 14 open reading frame 100".

Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934 . PMID 11042152.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Behrends U, Schneider I, Rössler S, et al. (2003). "Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries". Int. J. Cancer. 106 (2): 244–51. doi: 10.1002/ijc.11208 . PMID 12800201.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000050130 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000005078 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16166642-5] Kadoya T, Khurana A, Tcherpakov M, Bromberg KD, Didier C, Broday L, Asahara T, Bhoumik A, Ronai Z (Sep 2005). "JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity". Mol Cell Biol. 25 (19): 8619–30. doi:10.1128/MCB.25.19.8619-8630.2005. PMC 1265750 . PMID 16166642.

[pmid19269966-6] Tcherpakov M, Delaunay A, Toth J, Kadoya T, Petroski MD, Ronai ZA (Apr 2009). "Regulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP)". J Biol Chem. 284 (18): 12099–109. doi: 10.1074/jbc.M808222200 . PMC 2673279 . PMID 19269966.

[entrez-7] "Entrez Gene: C14orf100 chromosome 14 open reading frame 100".

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JKAMP

Related Research Articles

References

Further reading