Jeremy Kirk Nicholson | |
---|---|
Born | 19 August 1956 |
Nationality | British |
Alma mater | Liverpool University London University |
Known for | Metabonomics |
Scientific career | |
Fields | Biological chemistry |
Institutions | Birkbeck College, London University; London School of Pharmacy; Imperial College London; Murdoch University |
Website | profiles |
Jeremy K. Nicholson is a professor and pro vice chancellor of Health Sciences at Murdoch University in Perth, Western Australia, where he leads the Australian National Phenome Centre. [1] He is also an emeritus professor of Biological Chemistry at Imperial College London [ citation needed ] and was the director and principal investigator of the MRC-NIHR National Phenome Centre until 2018.
Nicholson obtained his BSc in Marine Biology with honours from Liverpool University in 1977 and his PhD in biochemistry from St Thomas's Hospital Medical School (King's College, London University) in 1980. He has worked at Birkbeck College, London University and at the London School of Pharmacy, becoming full Professor in 1992. In 1998, he became Professor and Head of Biological Chemistry at Imperial College London. Nicholson was appointed Head of the Department of Surgery and Cancer at Imperial College London in 2009. In December 2012, Nicholson became the Director of the MRC-NIHR National Phenome Centre and launched the International Phenome Centre Network (IPCN) in 2016. [2] He was made Emeritus Professor of Biological Chemistry at Imperial College London in 2018. Nicholson moved to Perth, Western Australia in 2018 to take up his role as Pro Vice Chancellor of Health Sciences at Murdoch University. [3]
Nicholson holds honorary professorships at twelve different universities. He also holds multiple professorships at the Chinese Academy of Sciences, of which he was elected as an Albert Einstein Honorary Professor in 2014. [4] Nicholson was recently appointed as a special advisor to the Minister of Health in Western Australia.
Nicholson is the founder director, chief scientist and chief scientist officer at Metabometrix Limited, an Imperial College London spin-off company incorporated in April 2000 and specializing in molecular phenotyping, clinical diagnostics and toxicological screening via metabonomics and metabolomics.[ citation needed ] He is also a founder and scientific advisor of Melico Sciences Limited incorporated in 2017 and specializing in metabolic life coaching.
Nicholson is known for having been an early pioneer in NMR-based metabonomics, [5] more commonly known as metabolomics or metabolic profiling. His research interests include spectroscopic and chemometric approaches to the investigation of disturbed metabolic processes in complex organisms.[ citation needed ]
He is an associate editor and frequent contributor to the Journal of Proteome Research (JPR).
Nicholson has received numerous grants and awards for his work, recent awards including:[ citation needed ]
Nicholson has published over 800 scientific papers.[ citation needed ] He has an H-index of 122 and is an ISI Highly Cited Researcher. [4]
Michael Smith was a British-born Canadian biochemist and businessman. He shared the 1993 Nobel Prize in Chemistry with Kary Mullis for his work in developing site-directed mutagenesis. Following a PhD in 1956 from the University of Manchester, he undertook postdoctoral research with Har Gobind Khorana at the British Columbia Research Council in Vancouver, British Columbia, Canada. Subsequently, Smith worked at the Fisheries Research Board of Canada Laboratory in Vancouver before being appointed a professor of biochemistry in the UBC Faculty of Medicine in 1966. Smith's career included roles as the founding director of the UBC Biotechnology Laboratory and the founding scientific leader of the Protein Engineering Network of Centres of Excellence (PENCE). In 1996 he was named Peter Wall Distinguished Professor of Biotechnology. Subsequently, he became the founding director of the Genome Sequencing Centre at the BC Cancer Research Centre.
Murdoch University is a public university in Perth, Western Australia, with campuses also in Singapore and Dubai. It began operations as the state's second university on 25 July 1973, and accepted its first undergraduate students in 1975. Its name is taken from Sir Walter Murdoch (1874–1970), the Founding Professor of English and former Chancellor of the University of Western Australia.
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy.
Metabolomics is the scientific study of chemical processes involving metabolites, the small molecule substrates, intermediates, and products of cell metabolism. Specifically, metabolomics is the "systematic study of the unique chemical fingerprints that specific cellular processes leave behind", the study of their small-molecule metabolite profiles. The metabolome represents the complete set of metabolites in a biological cell, tissue, organ, or organism, which are the end products of cellular processes. Messenger RNA (mRNA), gene expression data, and proteomic analyses reveal the set of gene products being produced in the cell, data that represents one aspect of cellular function. Conversely, metabolic profiling can give an instantaneous snapshot of the physiology of that cell, and thus, metabolomics provides a direct "functional readout of the physiological state" of an organism. There are indeed quantifiable correlations between the metabolome and the other cellular ensembles, which can be used to predict metabolite abundances in biological samples from, for example mRNA abundances. One of the ultimate challenges of systems biology is to integrate metabolomics with all other -omics information to provide a better understanding of cellular biology.
Sir Alan Roy Fersht is a British chemist at the MRC Laboratory of Molecular Biology, Cambridge, and an Emeritus Professor in the Department of Chemistry at the University of Cambridge. He was Master of Gonville and Caius College, Cambridge from 2012 to 2018. He works on protein folding, and is sometimes described as a founder of protein engineering.
Sir Colin Blakemore,, Hon was a British neurobiologist, specialising in vision and the development of the brain. He was Yeung Kin Man Professor of Neuroscience and senior fellow of the Hong Kong Institute for Advanced Study at City University of Hong Kong. He was a distinguished senior fellow in the Institute of Philosophy, School of Advanced Study, University of London and Emeritus Professor of Neuroscience at the University of Oxford and a past Chief Executive of the British Medical Research Council (MRC). He was best known to the public as a communicator of science but also as the target of a long-running animal rights campaign. According to The Observer, he was both "one of the most powerful scientists in the UK" and "a hate figure for the animal rights movement".
Richard Henderson is a British molecular biologist and biophysicist and pioneer in the field of electron microscopy of biological molecules. Henderson shared the Nobel Prize in Chemistry in 2017 with Jacques Dubochet and Joachim Frank. "Thanks to his work, we can look at individual atoms of living nature, thanks to cryo-electron microscopes we can see details without destroying samples, and for this he won the Nobel Prize in Chemistry."
Atta-ur-Rahman, h-index 75, with 36,000 citations is a Pakistani organic chemist and is currently serving as Professor Emeritus at the International Center for Chemical and Biological Sciences at the University of Karachi and as Chairman of PM Task Force on Science and Technology. He has twice served as the President of Pakistan Academy of Sciences. He was the Federal Minister of Science and Technology (2000-2002), Federal Minister of Education (2002) and Chairman Higher Education Commission with status of Federal Minister (2002-2008) He is also the President of the Network of Academies of Sciences in Countries of the Organisation of Islamic Countries (NASIC). After returning to Pakistan from Cambridge after completing his tenure as Fellow of Kings College, Cambridge University, he contributed to the development of the International Center for Chemical and Biological Sciences at the University of Karachi, and transforming the landscape of higher education, science and technology of Pakistan. He is Fellow of Royal Society (London), Life Fellow of Kings College, Cambridge University, UK.,, Academician Chinese Academy of Sciences and Professor Emeritus at University of Karachi
Sir Philip Cohen is a distinguished British biochemist known for his extensive contributions to the field of biochemistry, especially to the understanding of the role of reversible protein phosphorylation in cell regulation.
Dame Jean Olwen Thomas, is a Welsh biochemist, former Master of St Catharine's College, Cambridge, and Chancellor of Swansea University.
Dame Athene Margaret Donald is a British physicist. She is Professor Emerita of Experimental Physics at the University of Cambridge, and Master of Churchill College, Cambridge.
James Barber was a British senior research investigator and emeritus Ernst Chain professor of biochemistry at Imperial College London, Visiting Professor at the Polytechnic University of Turin and Visiting Canon Professor to Nanyang Technological University (NTU) in Singapore.
John Andrew Todd is a British geneticist who is Professor of Precision Medicine at the University of Oxford, director of the Wellcome Center for Human Genetics and the JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, in addition to Jeffrey Cheah Fellow in Medicine at Brasenose College. He works in collaboration with David Clayton and Linda Wicker to examine the molecular basis of type 1 diabetes.
Sir Gordon William Duff, is a British medical scientist and academic. He was principal of St Hilda's College, Oxford, from 2014 to 2021. He was Lord Florey Professor of Molecular Medicine at the University of Sheffield from 1991 to 2014.
Sir Stephen Patrick O'Rahilly is an Irish-British physician and scientist known for his research into the molecular pathogenesis of human obesity, insulin resistance and related metabolic and endocrine disorders.
Jens Nielsen is the CEO of BioInnovation Institute, Copenhagen, Denmark, and professor of systems biology at Chalmers University of Technology, Gothenburg, Sweden. He is also an adjunct professor at the Danish Technical University and the University of Copenhagen. Nielsen is the most cited researcher in the field of metabolic engineering, and he is the most cited researcher in Biology and Biochemistry in Sweden and Denmark. He is the only foreign member of all three academies in the US and he is also foreign member of the Chinese Academy of Engineering. He was the founding president of the International Metabolic Engineering Society. He has additionally founded several biotech companies.
Sharon Jayne Peacock is a British microbiologist who is Professor of Public Health and Microbiology in the Department of Medicine at the University of Cambridge. Peacock also sits on Cambridge University Council.
Royston "Roy" Goodacre is Chair in Biological Chemistry at the University of Liverpool. With training in both Microbiology and Pyrolysis-Mass Spectrometry, Goodacre runs a multidisciplinary Metabolomics and Raman spectroscopy research group in the Institute of Systems, Molecular and Integrative Biology (ISMIB), and leads ISMIB's Centre for Metabolomics Research and the Laboratory for Bioanalytical Spectroscopy.
Matthew John Fuchter is a British chemist who is a Professor of Chemistry at the University of Oxford. His research focuses on the development and application of novel functional molecular systems to a broad range of areas; from materials to medicine. He has been awarded both the Harrison-Meldola Memorial Prize (2014) and the Corday–Morgan Prizes (2021) of the Royal Society of Chemistry. In 2020 he was a finalist for the Blavatnik Awards for Young Scientists.
Elaine Holmes FAA is an Australian systems biologist, and chemist, who was elected a fellow of the Australian Academy of Science in 2023. She was awarded an ARC Laureate Fellowship in 2020. She is a computational biologist working in metabolomic phenotyping, spectrometry and translational clinical medicine, at Murdoch University, and also holds a chair at Imperial College.