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Sir Frank Macfarlane Burnet, usually known as Macfarlane or Mac Burnet, was an Australian virologist known for his contributions to immunology. He won a Nobel Prize in 1960 for predicting acquired immune tolerance. He also developed the theory of clonal selection.
Bcl-2, encoded in humans by the BCL2 gene, is the founding member of the Bcl-2 family of regulator proteins. BCL2 blocks programmed cell death (apoptosis) while other BCL2 family members can either inhibit or induce it. It was the first apoptosis regulator identified in any organism.
WEHI, previously known as the Walter and Eliza Hall Institute of Medical Research, and as the Walter and Eliza Hall Institute, is Australia's oldest medical research institute. Sir Frank Macfarlane Burnet, who won the Nobel Prize in 1960 for his work in immunology, was director from 1944 to 1965. Burnet developed the ideas of clonal selection and acquired immune tolerance. Later, Professor Donald Metcalf discovered and characterised colony-stimulating factors. As of 2015, the institute hosted more than 750 researchers who work to understand, prevent and treat diseases including blood, breast and ovarian cancers; inflammatory diseases (autoimmunity) such as rheumatoid arthritis, type 1 diabetes and coeliac disease; and infectious diseases such as malaria, HIV and hepatitis B and C.
The Australian Academy of Science was founded in 1954 by a group of distinguished Australians, including Australian Fellows of the Royal Society of London. The first president was Sir Mark Oliphant. The academy is modelled after the Royal Society and operates under a Royal charter; as such, it is an independent body, but it has government endorsement. The Academy Secretariat is in Canberra, at the Shine Dome.
Jacques Francis Albert Pierre Miller AC FRS FAA is a French-Australian research scientist. He is known for having discovered the function of the thymus and for the identification of mammalian species of the two major subsets of lymphocytes and their function.
Philip Leder was an American geneticist.
Suzanne Cory is an Australian molecular biologist. She has worked on the genetics of the immune system and cancer and has lobbied her country to invest in science. She is married to fellow scientist Jerry Adams, also a WEHI scientist, whom she met while studying for her PhD at the University of Cambridge, England.
William James Peacock, is an Australian molecular biologist who was Chief Scientist of Australia (2006–2008), President of the Australian Academy of Science (2002–2006) and Chief of CSIRO Plant Industry (1978–2003).
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William Hayes FRCPI FRS FRSE LLD was an Irish geneticist.
Gene expression profiling has revealed that diffuse large B-cell lymphoma (DLBCL) is composed of at least 3 different sub-groups, each having distinct oncogenic mechanisms that respond to therapies in different ways. Germinal Center B-Cell like (GCB) DLBCLs appear to arise from normal germinal center B cells, while Activated B-cell like (ABC) DLBCLs are thought to arise from postgerminal center B cells that are arrested during plasmacytic differentiation. The differences in gene expression between GCB DLBCL and ABC DLBCL are as vast as the differences between distinct types of leukemia, but these conditions have historically been grouped together and treated as the same disease.
Douglas James Hilton is an Australian molecular biologist. He is the CEO of CSIRO and immediate past Director of the Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia. His research has focused on cytokines, signal transduction pathways and the regulation of blood cell formation (hematopoiesis). Hilton was the President of the Association of the Australian Medical Research Institutes (AAMRI) from 2014-16.
Sir Melvyn Francis Greaves is a British cancer biologist, and Professor of Cell Biology at the Institute of Cancer Research (ICR) in London. He is noted for his research into childhood leukaemia and the roles of evolution in cancer, including important discoveries in the genetics and molecular biology underpinning leukaemia.
Jane Visvader is a scientist specialising in breast cancer research who works for the Walter and Eliza Hall Institute in Melbourne, Australia. She is the joint head of the Breast Cancer Laboratory with Geoff Lindeman.
Georgia Chenevix-Trench is an Australian cancer researcher who investigates genetic predispositions to cancer.
Peter Malcolm Colman is the head of the structural biology division at the Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia.
David James Kemp was an Australian plant geneticist and parasitologist.
Alan Frederick Cowman AC, FRS, FAA, CorrFRSE, FAAHMS, FASP, FASM is an internationally acclaimed malaria researcher whose work specialises in researching the malaria-causing parasite, Plasmodium falciparum, and the molecular mechanisms it uses to evade host responses and antimalarial drugs. As of May 2024, he is the deputy directory and Laboratory Head of the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne, and his laboratory continues to work on understanding how Plasmodium falciparum, infects humans and causes disease. He was elected as a fellow of the Royal Society in 2011 and awarded the Companion of the Order of Australia in 2019 for his "eminent service to the biological sciences, notably to molecular parasitology, to medical research and scientific education, and as a mentor."
Grant Robert Sutherland is a retired Australian human geneticist and celebrated cytogeneticist. He was the Director, Department of Cytogenetics and Molecular Genetics, Adelaide Women's and Children's Hospital for 27 years (1975-2002), then became the Foundation Research Fellow there until 2007. He is an Emeritus Professor in the Departments of Paediatrics and Genetics at the University of Adelaide.
Lynn Corcoran is an American–Australian immunologist who is Professor of Immunology at the Walter and Eliza Hall Institute. Her research considers cancer, parasitology and immunology, with a focus on B cells biology. She was inducted into the Victorian government's Honour Roll in 2013.
References
- ↑ "ACRF Medical Research Advisory Committee". Australian Cancer Research Foundation. Archived from the original on 18 May 2016. Retrieved 10 June 2010.
- ↑ "Lemberg Medal Winners". Australian Society for Biochemistry and Molecular Biology. Retrieved 31 January 2024.[ permanent dead link ]
- ↑ "Jerry Adams-Biography". Royal Society. Retrieved 22 February 2017.
- ↑ "Elected Fellows of the Royal Society of Victoria - The Royal Society of Victoria". The Royal Society of Victoria. Retrieved 27 June 2018.
- ↑ "Macfarlane Burnet Medal and Lecture". Australian Academy of Science. Retrieved 22 February 2017.
- ↑ "29 new Fellows elected". AAHMS – Australian Academy of Health and Medical Sciences. 26 October 2021. Retrieved 29 October 2021.
