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Sir Martin John EvansFLSW is an English biologist who, with Matthew Kaufman, was the first to culture mice embryonic stem cells and cultivate them in a laboratory in 1981. He is also known, along with Mario Capecchi and Oliver Smithies, for his work in the development of the knockout mouse and the related technology of gene targeting, a method of using embryonic stem cells to create specific gene modifications in mice. In 2007, the three shared the Nobel Prize in Physiology or Medicine in recognition of their discovery and contribution to the efforts to develop new treatments for illnesses in humans.
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Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc was the first gene to be discovered in this family, due to homology with the viral gene v-myc.
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Ralph Lawrence Brinster is an American geneticist, National Medal of Science laureate, and Richard King Mellon Professor of Reproductive Physiology at the School of Veterinary Medicine, University of Pennsylvania.
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Holly Brown-Borg is an American biologist and biogerontologist best known for her research on the regulation of lifespan by growth hormone. She is the Chester Fritz Distinguished Professor of Pharmacology, Physiology & Therapeutics at the University of North Dakota School of Medicine and Health Sciences.
Anindya Dutta is an Indian-born American biochemist and cancer researcher, a Chair of the Department of Genetics at the University of Alabama at Birmingham School of Medicine since 2021, who has served as Chair of the Department of Biochemistry and Molecular Genetics at the University of Virginia School of Medicine in 2011–2021. Dutta's research has focused on the mammalian cell cycle with an emphasis on DNA replication and repair and on noncoding RNAs. He is particularly interested in how de-regulation of these processes promote cancer progression. For his accomplishments he has been elected a Fellow of the American Association for the Advancement of Science, received the Ranbaxy Award in Biomedical Sciences, the Outstanding Investigator Award from the American Society for Investigative Pathology, the Distinguished Scientist Award from the University of Virginia and the Mark Brothers Award from the Indiana University School of Medicine.
Carole LaBonne is a Developmental and Stem Cell Biologist at Northwestern University. She is the Erastus O. Haven Professor of Life Sciences, and Chair of the Department of Molecular Biosciences.
Carla Beth Green is an American neurobiologist and chronobiologist. She is a professor in the Department of Neuroscience and a Distinguished Scholar in Neuroscience at the University of Texas Southwestern Medical Center. She is the former president of the Society for Research on Biological Rhythms (SRBR), as well as a satellite member of the International Institute for Integrative Sleep Medicine at the University of Tsukuba in Japan.
Richard Palmiter is a cellular biologist. He was born in Poughkeepsie, NY and later went on to earn a BA in Zoology from Duke University and a PhD in Biological Sciences from Stanford University. He is Jude Gautier's grandfather. He is employed with the University of Washington where he is a professor of biochemistry and genome sciences. His current research involves developing a deeper understanding of Parkinson's disease. His most notable research is a collaboration with Dr. Ralph Brinster where they injected purified DNA into a single-cell mouse embryo, showing transmission of the genetic material to subsequent generations for the first time.
Lynn Corcoran is an American–Australian immunologist who is Professor of Immunology at the Walter and Eliza Hall Institute. Her research considers cancer, parasitology and immunology, with a focus on B cells biology. She was inducted into the Victorian government's Honour Roll in 2013.
References
- ↑ Researchers at Brown Profile
- ↑ Gene Targeting
- ↑ "Benefits of Missing MYC". The Scientist Magazine®.
