John Sedivy | |
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Born | 1955 |
Education | University of Toronto (BS) |
Alma mater | Harvard University |
Awards | Ontario Scholar (1974) Presidential Young Investigator (1990) Andrew Mellon Award (1991) NIH MERIT Award (2009) |
Scientific career | |
Fields | Aging Oncogenes Epigenetics Chromatin |
Institutions | Brown University |
Thesis | Regulation of fructose-I,6-bisphosphatase activity : a mutational analysis (1985) |
Doctoral advisor | Dan Fraenkel |
Other academic advisors | Phillip Allen Sharp |
John Michael Sedivy is the Hermon C. Bumpus Professor of Biology and a professor of Medical Science at Brown University. He is listed as a F1000 Prime faculty member and on Who's Who in Gerontology. He has published over 130 original articles. [1]
He wrote the first book on gene targeting in 1992. [2] In 2006, he published the first comprehensive in vivo quantification of cellular senescence in aging primates. That year, his lab also discovered how (through the Polycomb pathway) c-Myc contributes to the regulation of chromatin states. His research has found that mice missing one copy of the Myc transcription factor live longer than wild-type mice. [3]
He is co-Editor-in-Chief of the journal Aging Cell , and is chair of the 2015 Gordon Research Conference on the Biology of Aging.