Juan G. Santiago an American academic. He is the Charles Lee Powell Foundation Professor of Mechanical Engineering at Stanford University and the Director of the Stanford Microfluidics Laboratory. His research includes studies of microscale transport and fluid flow phenomena, electrokinetics phenomena, two-phase flow, and coupled flow and reaction processes. This research has applications to microfluidics systems for on-chip chemical and biochemical analysis, biophysics studies of DNA and CRISPR, two-phase flow devices, and capacitive deionization technologies. Applications of this work also include molecular diagnostics, DNA mapping and sequencing, electronics cooling, and the production of drinking water. He serves as the Founding Editor-in-Chief of the Cambridge University Press journal Flow. His work is cited more than 1500 times per year and has an h index of 91. He has authored and co-authored over 220 journal papers and 250 conference papers, and he is an inventor in 60 issued patents. [1] He has played a significant role in co-founding several companies specializing in the field of microfluidics. [2]
Santiago was born in San Juan, Puerto Rico, the son of Cuban Refugees. His parents worked hard to provide for their family. Santiago started working various part-time jobs from age 13 in order to contribute to the family. In high school, he worked cutting grass, delivering newspapers, delivering phone books, and bagging groceries. In college, he worked as a movie theater attendant and cleaner, a worker at an airplane parts warehouse, delivering Dominos Pizza, as a clerk at KB Toys, a stagehand for a Spanish-channel TV show named Sábado Gigante, a box-car loader for UPS, and a liquor store clerk in Little Havana. He practiced various forms of martial arts and served as captain of his high-school wrestling team. Santiago also held a paying job as a martial arts instructor. [3]
Santiago started his undergraduate career at Florida International University (FIU), and later transferred to the University of Florida. He earned his Bachelor of Science [4] in Mechanical Engineering in 1990, graduating first in his class. He then attended the University of Illinois at Urbana-Champaign, Mechanical Engineering, where in 1992 he earned his Master of Science. Santiago earned his PhD at the University of Illinois at Urbana-Champaign, Mechanical Engineering in 1995. [5]
Santiago joined Stanford University as a faculty member in Mechanical Engineering in 1998. His research involves the study of micron-scale transport phenomena, electrokinetics, two-phase flow, and the design of microfluidic devices. His research has applications to on-chip biological assays to detect and identify DNA, on-chip chemical reactions, electronics cooling, and the desalination of water to create drinking water. Along with Professor Carl Meinhart of UCSB, Santiago co-invented a technique to quantify fluid velocities at small scales called micro-PIV. [6] An example contribution from his lab is a microfluidic device capable of detecting the RNA of the COVID-19 virus within just 30 minutes starting from a nasal swab. [7] His team also develops systems designed to purify brackish water by removing salt and other contaminants, in order to make it safe for drinking. [8]
In 2022, Santiago was elected as the Charles Lee Powell Foundation Professor of Mechanical Engineering at Stanford University. He serves as the Vice Chair for the Mechanical Engineering Department. His current research is focused on various areas, including the creation of microfluidic systems for DNA mapping, identification of cancer markers, and the development of flow electrode systems for desalination and harvesting of lithium.
Santiago is a member of multiple American engineering organizations including the American Institute for Medical and Biological Engineering, American Physical Society, and the American Society of Mechanical Engineering. [9]
Santiago has been recognized with many academic and research awards over the years. He was awarded the Presidential Early Career Award for Scientists and Engineers in 2004. He was awarded the AES Electrophoresis Society Lifetime Achievement Award. [10] He was given the Outstanding Alumnus Award from the Mechanical Engineering Department of the University of Florida in 2008. He was elected Fellow of the American Physical Society (2010), Fellow of the American Society of Mechanical Engineering (2012), and Fellow of the American Institute for Medical and Biological Engineering (2016). He was awarded the Cozzarelli Prize for work on cell analysis [11] by the National Academy of Sciences in 2017. In 2022, he was elected to the American Academy of Arts and Sciences. [12] In 2022, he was also elected to National Academy of Inventors. [13]
Electrohydrodynamics (EHD), also known as electro-fluid-dynamics (EFD) or electrokinetics, is the study of the dynamics of electrically charged fluids. Electrohydrodynamics (EHD) is a joint domain of electrodynamics and fluid dynamics mainly focused on the fluid motion induced by electric fields. EHD, in its simplest form, involves the application of an electric field to a fluid medium, resulting in fluid flow, form, or properties manipulation. These mechanisms arise from the interaction between the electric fields and charged particles or polarization effects within the fluid. The generation and movement of charge carriers (ions) in a fluid subjected to an electric field are the underlying physics of all EHD-based technologies.
Parviz Moin is a fluid dynamicist. He is the Franklin P. and Caroline M. Johnson Professor of Mechanical Engineering at Stanford University. Moin has been listed as an ISI Highly Cited author in engineering.
John A. Rogers is a physical chemist and a materials scientist. He is currently the Louis Simpson and Kimberly Querrey Professor of Materials Science and Engineering, Biomedical Engineering, and Neurological Surgery at Northwestern University.
Howard Alvin Stone is the Donald R. Dixon '69 and Elizabeth W. Dixon Professor in Mechanical and Aerospace Engineering at Princeton University. His field of research is in fluid mechanics, chemical engineering and complex fluids. He became an Editor of the Annual Review of Fluid Mechanics in 2021.
Mehmet Toner is a Turkish biomedical engineer. He is currently the Helen Andrus Benedict Professor of Surgery at Massachusetts General Hospital (MGH) and Harvard Medical School, with a joint appointment as professor at the Harvard-MIT Division of Health Sciences and Technology (HST).
Jan Drewes Achenbach was a professor emeritus at Northwestern University. Achenbach was born in the northern region of the Netherlands, in Leeuwarden. He studied aeronautics at Delft University of Technology, which he finished with a M.Sc. degree in 1959. Thereafter, he went to the United States, Stanford University, where he received his Ph.D. degree in 1962. After working for a year as a preceptor at Columbia University, he was then appointed as assistant professor at Northwestern University.
Adam Ezra Cohen is a Professor of Chemistry, Chemical Biology, and Physics at Harvard University. He has received the Presidential Early Career Award for Scientists and Engineers and been selected by MIT Technology Review to the TR35 list of the world's top innovators under 35.
Steve Wereley is a professor of mechanical engineering at Purdue University. His areas of research include Micro- and Nanofluidics, Particle Image Velocimetry, Opto-microfluidics and bio-MEMS. He is the co-inventor of micro-PIV.
Stephen Ronald Quake is an American physicist, inventor, and entrepreneur.
Jennifer Anne Doudna is an American biochemist who has pioneered work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. Doudna was one of the first women to share a Nobel in the sciences. She received the 2020 Nobel Prize in Chemistry, with Emmanuelle Charpentier, "for the development of a method for genome editing." She is the Li Ka Shing Chancellor's Chair Professor in the department of chemistry and the department of molecular and cell biology at the University of California, Berkeley. She has been an investigator with the Howard Hughes Medical Institute since 1997.
Suman Chakraborty is a professor at the Indian Institute of Technology Kharagpur and Sir J. C. Bose National Fellow. He has been the first in the history of IIT Kharagpur to be bestowed by the National Award for Teachers in the Higher Education Category by the honourable President of India. He is also Institute Chair Professor Awardee of 2023. He has served as the Dean, Research and Development, Associate Dean and the Head of the School of Medical Science and Technology of the Institute. He has also been National Academy of Engineering Chair Professor. He joined the Institute in 2002 as Assistant Professor and has been a Full Professor since 2008.
Induced-charge electrokinetics in physics is the electrically driven fluid flow and particle motion in a liquid electrolyte. Consider a metal particle in contact with an aqueous solution in a chamber/channel. If different voltages apply to the end of this chamber/channel, electric field will generate in this chamber/channel. This applied electric field passes through this metal particle and causes the free charges inside the particle migrate under the skin of particle. As a result of this migration, the negative charges move to the side which is close to the positive voltage while the positive charges move to the opposite side of the particle. These charges under the skin of the conducting particle attract the counter-ions of the aqueous solution; thus, the electric double layer (EDL) forms around the particle. The EDL sign on the surface of the conducting particle changes from positive to negative and the distribution of the charges varies along the particle geometry. Due to these variations, the EDL is non-uniform and has different signs. Thus, the induced zeta potential around the particle, and consequently slip velocity on the surface of the particle, vary as a function of the local electric field. Differences in magnitude and direction of slip velocity on the surface of the conducting particle effects the flow pattern around this particle and causes micro vortices. Yasaman Daghighi and Dongqing Li, for the first time, experimentally illustrated these induced vortices around a 1.2 mm diameter carbon-steel sphere under the 40V/cm direct current (DC) external electric filed. Chenhui Peng et al. also experimentally showed the patterns of electro-osmotic flow around an Au sphere when alternating current (AC) is involved . Electrokinetics here refers to a branch of science related to the motion and reaction of charged particles to the applied electric filed and its effects on its environment. It is sometimes referred as non-linear electrokinetic phenomena as well.
Nadine Aubry is an American engineer. She previously served as Provost and Senior Vice President of Tufts University. She is an elected Fellow of the American Association for the Advancement of Science, the American Society of Mechanical Engineers, the American Physical Society, the American Institute of Aeronautics and Astronautics, the National Academy of Inventors, and the American Academy of Arts and Sciences. In 2009, she was the Raymond J. Lane Distinguished Professor and University Professor at Carnegie Mellon University.
Klavs Flemming Jensen is a chemical engineer who is currently the Warren K. Lewis Professor at the Massachusetts Institute of Technology (MIT).
Morteza (Mory) Gharib is the Hans W. Liepmann Professor of Aeronautics and Bio-Inspired Engineering at Caltech.
Gareth Huw McKinley is Professor of Teaching Innovation in the Department of Mechanical Engineering at Massachusetts Institute of Technology (MIT).
Amy Elizabeth Herr is an American professor. She is the John D. and Catherine T. MacArthur Professor at the University of California, Berkeley, where she is attached to the Department of Bioengineering. At Berkeley she was also the founding executive director of the Bakar Bioenginuity Hub. Herr is a Chan Zuckerberg BioHub Investigator and the Chief Technology Officer of the Chan Zuckerberg Biohub Network, a fellow of both the National Academy of Inventors and the American Institute of Medical and Biological Engineering, as well as a co-founder of Zephyrus Biosciences, a biotechnology company that was acquired by Bio-Techne.
Kiana Aran is a biomedical entrepreneur and Associate Professor at both UC San Diego's School of Medicine and UC San Diego's Jacobs School of Engineering in the Department of Bioengineering. She is also the Chief Innovation Officer at Paragraf Ltd. Paragraf, a UK-based semi-conductor company, acquired Cardea Bio Inc., which she co-founded and ran as the Chief Science Offer. She has also helped co-found CRISPR QC Inc. that offers a CRISPR Analytics Platform that helps pharma and biotech companies optimize their gene editing research. Her overall research and inventions are focused around developing technologies and bioelectronics for multi-omics studies and applications, especially when they enable products and technologies for studying the mechanisms of healthy aging. She became known as the pioneer of fusing CRISPR and electronics, resulting in the CRISPR-chip technology that is being used to improve the quality of genotyping and gene editing. She was awarded the 2021 Nature – Estée Lauder Research Award for Inspiring Women in Science.
Martin Zdenek Bazant is an American chemical engineer, mathematician, physicist, and academic. He is the E. G. Roos (1944) Professor of Chemical Engineering and Mathematics at the Massachusetts Institute of Technology (MIT). From 2016 to 2020, he served as executive officer of the department of chemical engineering.
Cullen R. Buie is an African American mechanical engineer specializing in microbial fuel cells.