Justicidin A

Last updated
Justicidin A
Justicidin A.svg
Names
Preferred IUPAC name
9-(2H-1,3-Benzodioxol-5-yl)-4,6,7-trimethoxynaptho[2,3-c]furan-1(3H)-one
Other names
Diphyllin methyl ether
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
KEGG
PubChem CID
UNII
  • InChI=1S/C22H18O7/c1-24-16-7-12-13(8-17(16)25-2)21(26-3)14-9-27-22(23)20(14)19(12)11-4-5-15-18(6-11)29-10-28-15/h4-8H,9-10H2,1-3H3
    Key: ANFSXHKDCKWWDB-UHFFFAOYSA-N
  • COC1=C(C=C2C(=C1)C(=C3C(=C2OC)COC3=O)C4=CC5=C(C=C4)OCO5)OC
Properties
C22H18O7
Molar mass 394.379 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Justicidin A is an organic compound isolated from Justicia procumbens . It is classified as a lignan. [1] [2] The compound may possess cytotoxic effects. [3]

References

  1. ↑ Umezawa, Toshiaki (2003). "Diversity in lignan biosynthesis". Phytochemistry Reviews. 2 (3): 371–390. Bibcode:2003PChRv...2..371U. doi:10.1023/B:PHYT.0000045487.02836.32. S2CID   6276953.
  2. ↑ Xiong, Lu; Bi, Ming-Gang; Wu, Song; Tong, Yuan-Feng (2012). "Total synthesis of 6′-hydroxyjusticidin A". Journal of Asian Natural Products Research. 14 (4): 322–6. doi:10.1080/10286020.2011.653561. PMID   22375869. S2CID   26689006.
  3. ↑ Fukamiya, Narihiko; Lee, Kuo-Hsiung (1986). "Antitumor Agents, 81. Justicidin-A and Diphyllin, Two Cytotoxic Principles from Justicia procumbens". Journal of Natural Products. 49 (2): 348–50. doi:10.1021/np50044a030. PMID   3734816.


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