KIF20A

Last updated
KIF20A
Identifiers
Aliases KIF20A , MKLP2, RAB6KIFL, kinesin family member 20A
External IDs OMIM: 605664 MGI: 1201682 HomoloGene: 38093 GeneCards: KIF20A
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005733

NM_001166406
NM_001166407
NM_009004

RefSeq (protein)

NP_005724

NP_001159878
NP_001159879
NP_033030

Location (UCSC) Chr 5: 138.18 – 138.19 Mb Chr 18: 34.62 – 34.63 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Kinesin-like protein KIF20A is a protein that in humans is encoded by the KIF20A gene. [5] [6] [7]

Contents

Interactions

KIF20A has been shown to interact with RAB6A. [8] [9]

Related Research Articles

RAB6A

Ras-related protein Rab-6A is a protein that in humans is encoded by the RAB6A gene located in the eleventh chromosome. Its main function is the regulation of protein transport from the Golgi complex to the endoplasmic reticulum and the exocytosis along with the microtubules.

KIF1B

Kinesin-like protein KIF1B is a protein that in humans is encoded by the KIF1B gene.

KIF5B

Kinesin-1 heavy chain is a protein that in humans is encoded by the KIF5B gene.

KIF4A

Chromosome-associated kinesin KIF4A is a protein that in humans is encoded by the KIF4A gene.

KIF22

Kinesin-like protein KIF22 is a protein that in humans is encoded by the KIF22 gene.

KIF2C

Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene.

KIF3A

Kinesin-like protein KIF3A is a protein that in humans is encoded by the KIF3A gene.

KIF3B

Kinesin family member 3B (KIF3B) is a protein that in humans is encoded by the KIF3B gene. KIF3B is an N-type protein that complexes with two other kinesin proteins to form two-headed anterograde motors. First, KIF3B forms a heterodimer with KIF3A (kinesin family member 3A;, that is membrane-bound and has ATPase activity. Then KIFAP3 binds to the tail domain to form a heterotrimeric motor. This motor has a plus end-directed microtubule sliding activity that exhibits a velocity of ∼0.3 μm/s a. There are 14 kinesin protein families and KIF3B is part of the Kinesin-2 family, of kinesins that can all form heterotrimeric complexes. Expression of the three motor subunits is ubiquitous. The KIG3A/3B/KAP3 motors can transport 90 to 160 nm in diameter organelles.

KIF5A

Kinesin heavy chain isoform 5A is a protein that in humans is encoded by the KIF5A gene.

RAB21

Ras-related protein Rab-21 is a protein that in humans is encoded by the RAB21 gene.

KIF14

Kinesin-like protein KIF14 is a protein that in humans is encoded by the KIF14 gene.

KIFC1

Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene.

RAB6B

Ras-related protein Rab-6B is a protein that in humans is encoded by the RAB6B gene.

KIF17

Kinesin-like protein KIF17 is a protein that in humans is encoded by the KIF17 gene. KIF17 and its close relative, C. elegans OSM-3, are members of the kinesin-2 family of plus-end directed microtubule-based motor proteins. In contrast to heterotrimeric kinesin-2 motors, however, KIF17 and OSM-3 form distinct homodimeric complexes. Homodimeric kinesin-2 has been implicated in the transport of NMDA receptors along dendrites for delivery to the dendritic membrane, whereas both heterotrimeric and homodimeric kinesin-2 motors function cooperatively in anterograde intraflagellar transport (IFT) and cilium biogenesis.

KIF2A

Kinesin-like protein KIF2A is a protein that in humans is encoded by the KIF2A gene.

KIF3C

Kinesin-like protein KIF3C is a protein that in humans is encoded by the KIF3C gene.

KIF1A

Kinesin-like protein KIF1A, also known as axonal transporter of synaptic vesicles or microtubule-based motor KIF1A, is a protein that in humans is encoded by the KIF1A gene.

Kinesin family member 11

Kinesin-5 is a molecular motor protein that is essential in mitosis. Kinesin-5 proteins are members of kinesin superfamily, which are nanomotors that move along microtubule tracks in the cell. Named from studies in the early days of discovery, it is also known as kinesin family member 11, encoded by the KIF11 gene, or as BimC, Eg5 or N-2, based on the founding members of this kinesin family. The term kinesin-5 has been recommended based on a standardized nomenclature adopted by the scientific community.

RABGAP1

RAB GTPase activating protein 1 is a protein in humans that is encoded by the RABGAP1 gene.

KIF15

Kinesin family member 15 is a protein that in humans is encoded by the KIF15 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000112984 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000003779 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Miki H, Setou M, Kaneshiro K, Hirokawa N (June 2001). "All kinesin superfamily protein, KIF, genes in mouse and human". Proc Natl Acad Sci U S A. 98 (13): 7004–11. Bibcode:2001PNAS...98.7004M. doi: 10.1073/pnas.111145398 . PMC   34614 . PMID   11416179.
  6. Lai F, Fernald AA, Zhao N, Le Beau MM (July 2000). "cDNA cloning, expression pattern, genomic structure and chromosomal location of RAB6KIFL, a human kinesin-like gene". Gene. 248 (1–2): 117–25. doi:10.1016/S0378-1119(00)00135-9. PMID   10806357.
  7. "Entrez Gene: KIF20A kinesin family member 20A".
  8. Echard A, Jollivet F, Martinez O, Lacapère JJ, Rousselet A, Janoueix-Lerosey I, Goud B (January 1998). "Interaction of a Golgi-associated kinesin-like protein with Rab6". Science. 279 (5350): 580–5. Bibcode:1998Sci...279..580E. doi:10.1126/science.279.5350.580. PMID   9438855.
  9. Echard A, Opdam FJ, de Leeuw HJ, Jollivet F, Savelkoul P, Hendriks W, Voorberg J, Goud B, Fransen JA (November 2000). "Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms". Mol. Biol. Cell. 11 (11): 3819–33. doi:10.1091/mbc.11.11.3819. PMC   15039 . PMID   11071909.

Further reading