KIF3C

KIF3C
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3B6V
Identifiers
Aliases	KIF3C , kinesin family member 3C
External IDs	OMIM: 602845 MGI: 107979 HomoloGene: 55640 GeneCards: KIF3C
Gene location (Human) Chr. Chromosome 2 (human) [1] Band 2p23.3 Start 25,926,598 bp [1] End 25,982,749 bp [1]
Gene location (Mouse) Chr. Chromosome 12 (mouse) [2] Band 12 A1.1|12 1.77 cM Start 3,365,132 bp [2] End 3,406,494 bp [2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • microtubule binding • microtubule motor activity • nucleotide binding • ATPase activity • cytoskeletal motor activity • ATP binding Cellular component • cytoplasm • cytosol • ciliary tip • microtubule • cytoskeleton • kinesin complex • cilium Biological process • microtubule-based movement • antigen processing and presentation of exogenous peptide antigen via MHC class II • organelle transport along microtubule • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum • intraciliary transport involved in cilium assembly Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	3797	16570
Ensembl	ENSG00000084731	ENSMUSG00000020668
UniProt	O14782	O35066
RefSeq (mRNA)	NM_002254	NM_008445
RefSeq (protein)	NP_002245	NP_032471
Location (UCSC)	Chr 2: 25.93 – 25.98 Mb	Chr 12: 3.37 – 3.41 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Kinesin-like protein KIF3C is a protein that in humans is encoded by the KIF3C gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000084731 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000020668 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Sardella M, Navone F, Rocchi M, Rubartelli A, Viggiano L, Vignali G, Consalez GG, Sitia R, Cabibbo A (Apr 1998). "KIF3C, a novel member of the kinesin superfamily: sequence, expression, and mapping to human chromosome 2 at 2p23". Genomics. 47 (3): 405–8. doi:10.1006/geno.1997.5123. PMID   9480755.
6. "Entrez Gene: KIF3C kinesin family member 3C".

Further reading

• Davidovic L, Jaglin XH, Lepagnol-Bestel AM, et al. (2008). "The fragile X mental retardation protein is a molecular adaptor between the neurospecific KIF3C kinesin and dendritic RNA granules". Hum. Mol. Genet. 16 (24): 3047–58. doi: 10.1093/hmg/ddm263 . PMID   17881655.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Elenich LA, Nandi D, Kent AE, et al. (1999). "The complete primary structure of mouse 20S proteasomes". Immunogenetics. 49 (10): 835–42. doi:10.1007/s002510050562. PMID   10436176. S2CID   20977116.
• Muresan V, Abramson T, Lyass A, et al. (1998). "KIF3C and KIF3A form a novel neuronal heteromeric kinesin that associates with membrane vesicles". Mol. Biol. Cell. 9 (3): 637–52. doi:10.1091/mbc.9.3.637. PMC   25292 . PMID   9487132.
• Yang Z, Goldstein LS (1998). "Characterization of the KIF3C neural kinesin-like motor from mouse". Mol. Biol. Cell. 9 (2): 249–61. doi:10.1091/mbc.9.2.249. PMC   25248 . PMID   9450952.
• Telford EA, Wightman P, Leek J, et al. (1998). "cDNA cloning, genomic organization, and chromosomal localization of a novel human gene that encodes a kinesin-related protein highly similar to mouse Kif3C". Biochem. Biophys. Res. Commun. 242 (2): 407–12. doi:10.1006/bbrc.1997.7977. PMID   9446808.

External links

• Overview of all the structural information available in the PDB for UniProt : O14782 (Human Kinesin-like protein KIF3C) at the PDBe-KB .