KIFC1

KIFC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2REP
Identifiers
Aliases	KIFC1 , HSET, KNSL2, kinesin family member C1
External IDs	OMIM: 603763 MGI: 2137414 HomoloGene: 83229 GeneCards: KIFC1
Gene location (Human)
Chr.	Chromosome 6 (human)
End	33,409,896 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	27,151,557 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; bone marrow; ; lymph node; ; appendix; ; stromal cell of endometrium; ; bone marrow cells; ; duodenum; ; placenta; ; rectum; ; thymus;
	Top expressed in
	bone marrow; ; yolk sac; ; urethra; ; thymus; ; placenta; ; ganglionic eminence; ; main bronchus; ; spermatocyte; ; blood vessel; ; mirror;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding ; microtubule binding ; ATPase activity ; ATP binding ; microtubule motor activity ; minus-end-directed microtubule motor activity ;
Cellular component	cytoplasm ; endosome ; membrane ; kinesin complex ; spindle ; microtubule organizing center ; early endosome ; microtubule ; cytoskeleton ; nucleus ; mitotic spindle ;
Biological process	cell division ; mitotic spindle assembly ; spermatogenesis ; mitotic sister chromatid segregation ; cell cycle ; mitotic metaphase plate congression ; microtubule-based movement ;
	Sources:Amigo / QuickGO
Orthologs
	3833
	16580
	ENSG00000233450 ; ENSG00000204197 ; ENSG00000237649 ; ENSG00000056678 Contents Function ; References ; Further reading ; External links ;
	ENSMUSG00000024301
	Q9BW19
	Q9QWT9
	NM_002263
	NM_016761 ; NM_053173
	NP_002254
	NP_001182227
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene.^[5]^[6]

Function

The protein KifC1 is a member of kinesin-14 family. KifC1 consists of C-terminal motor domain, superhelical stalk and N-terminal tail domain. Tail and motor domains contain microtubule-binding sites. This kinesin moves towards the minus-end of microtubule and has an ability to slide or crosslink microtubules. KifC1 functions during mitotic spindle formation.

Related Research Articles

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References

1 2 3 ENSG00000204197, ENSG00000237649, ENSG00000056678 GRCh38: Ensembl release 89: ENSG00000233450, ENSG00000204197, ENSG00000237649, ENSG00000056678 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024301 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Ando A, Kikuti YY, Kawata H, Okamoto N, Imai T, Eki T, Yokoyama K, Soeda E, Ikemura T, Abe K (Feb 1994). "Cloning of a new kinesin-related gene located at the centromeric end of the human MHC region". Immunogenetics. 39 (3): 194–200. doi:10.1007/bf00241260. PMID 8276466. S2CID 8880453.
↑ "Entrez Gene: KIFC1 kinesin family member C1".

External links

Overview of all the structural information available in the PDB for UniProt : Q9BW19 (Human Kinesin-like protein KIFC1) at the PDBe-KB .

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[refGRCh38Ensembl-1] 1 2 3 ENSG00000204197, ENSG00000237649, ENSG00000056678 GRCh38: Ensembl release 89: ENSG00000233450, ENSG00000204197, ENSG00000237649, ENSG00000056678 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024301 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8276466-5] Ando A, Kikuti YY, Kawata H, Okamoto N, Imai T, Eki T, Yokoyama K, Soeda E, Ikemura T, Abe K (Feb 1994). "Cloning of a new kinesin-related gene located at the centromeric end of the human MHC region". Immunogenetics. 39 (3): 194–200. doi:10.1007/bf00241260. PMID 8276466. S2CID 8880453.

[entrez-6] "Entrez Gene: KIFC1 kinesin family member C1".

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KIFC1

Contents

Function

Related Research Articles

References

Further reading

External links