Kefah Mokbel

Last updated

Professor

Kefah Mokbel

MBBS MS FRCS
Born1965
Syria
Education Concord College
Alma mater University of London
Occupation Surgeon

Professor Kefah Mokbel FRCS is currently the chair of breast cancer surgery and the multidisciplinary breast cancer program at the London Breast Institute of the Princess Grace Hospital part of HCA Healthcare, Professor (Honorary) of Breast Cancer Surgery at Brunel University London, an honorary consultant breast surgeon at St George's Hospital. Kefah Mokbel is the founder and current president of Breast Cancer Hope; a UK-based charity "dedicated to improving the quantity and quality of life in women diagnosed with breast cancer". [1] He was appointed as a substantive consultant breast surgeon at St George's Hospital NHS trust in February 2001. He was named in Tatler magazine's Best Doctors Guide as one of the featured "Top Breast Surgeons" in 2006, 2007 and 2013. [2] In November 2010 he was named in the Times magazine's list of Britain's Top Doctors. [3]

Contents

Personal details and education

Kefah Mokbel was born in 1965 in the currently occupied Golan Heights in Syria. At the end of junior high school, he was awarded a national scholarship after he passed the Brevet des collèges in Syria (1980). In 1983 he was awarded a scholarship to study medicine in the United Kingdom after completing the Syrian Baccalaureate national examination with full marks. Kefah Mokbel learned English in Eastbourne and then studied A levels in a boarding school (Concord College) in Shrewsbury. He graduated (MB, BS) from the University of London in 1990. He qualified as a Fellow of the Royal College of Surgeons (FRCS, England) in 1994. He was granted the Master of Surgery degree in 2000 by The Imperial College of Science, Technology and Medicine for his research in the field of molecular biology of breast cancer.

In 2002, Mokbel was appointed an Honorary Professor at The Brunel Institute of Cancer Genetics and Pharmacogenomics at Brunel University in recognition of his contribution to breast cancer research. [4] In 2005, he was appointed as a Reader in Breast Surgery at St George's University of London in recognition of his outstanding research contribution in the field of breast cancer. [5]

Clinical interests

Mokbel's clinical interests in the field of breast surgery include the early detection of breast cancer, breast ductoscopy, minimally-invasive breast surgery, sentinel node biopsy, skin-sparing mastectomy, breast reconstruction, cosmetic breast surgery, prevention of breast cancer, genetic predisposition, integrative oncology and the management of benign conditions including breast cysts, mastalgia and fibroadenomas. [6] Mokbel has extensive experience in the field of reconstructive and aesthetic breast surgery including augmentation mammoplasty (replacement of implants and correction of contracture), reduction mammoplasty and mastopexy.

Research interests

Mokbel's main research interest lies in the field of molecular biology and the clinical management of breast cancer. Furthermore, he has published several papers in the field of aesthetic breast surgery including breast reconstruction following mastectomy and augmentation mammoplasty using implants and fat transfer. His prolific research output includes over 400 published papers [7] in medical literature. According to Google Scholar Kefah Mokbel has 400 publications [8] which have been cited more than 8000 times with a H-index of 57 and an i10-index of 204. Furthermore, his research linked the SET domain containing protein 2 (SETD2) gene to human breast cancer. [9] He has also written 14 books [10] in various disciplines including surgery, oncology, breast cancer, and postgraduate medical education. Mokbel is a member of the editorial board of several international medical journals [11] [12] [13] [14] and a peer reviewer for medical journals including The Lancet.

In October 2017 Mokbel and his team reported through a metaanalysis that the use of hair dyes could be associated with a 20% increase in breast cancer risk. [15]


In October 2018, Mokbel and his team reported that the use of testosterone gel for hyposexual desire might not increase breast cancer risk among women using it. [16]

Press and media coverage

Kefah Mokbel has been also featured in many publications and interviews regarding breast cancer and surgery in the national and international media including: The Times, [17] The Daily Telegraph, [18] The Guardian, [19] New York Post, The BBC, [20] ITV, NBC Washington, [21] Hello Magazine, [22] ABC News, [23] MSN, Yahoo, The Daily Express, [24] The Independent, [25] The Medical Daily, [26] The Evening Standard., [27] The Mirror., [28] Marie Claire and British Sky Broadcasting. [29] He also writes medical articles for totalhealth and is one of totalhealth's specialist consultants. [30] [31] In 2013, Kefah Mokbel featured on BBC world news regarding the news that actress Angelina Jolie had preventative double mastectomy after finding that she is a BRCA1 gene carrier [32] He was depicted by Silas Carson in the BBC drama The C Word, about his real-life patient Lisa Lynch. [33]

Current appointments

Mokbel is currently the Chair of Breast Surgery at The London Breast Institute of The Princess Grace Hospital, the chair of the multidisciplinary breast cancer program of the London Breast Institute, Professor (Honorary) of Breast Cancer Surgery (Brunel University, London)[ citation needed ], Honorary Consultant Breast Surgeon at St George's Hospital (London, UK) and President of Breast Cancer Hope Foundation.

Related Research Articles

<span class="mw-page-title-main">Mastectomy</span> Surgical removal of one or both breasts

Mastectomy is the medical term for the surgical removal of one or both breasts, partially or completely. A mastectomy is usually carried out to treat breast cancer. In some cases, women believed to be at high risk of breast cancer have the operation as a preventive measure. Alternatively, some women can choose to have a wide local excision, also known as a lumpectomy, an operation in which a small volume of breast tissue containing the tumor and a surrounding margin of healthy tissue is removed to conserve the breast. Both mastectomy and lumpectomy are referred to as "local therapies" for breast cancer, targeting the area of the tumor, as opposed to systemic therapies, such as chemotherapy, hormonal therapy, or immunotherapy.

<span class="mw-page-title-main">Mammaplasty</span> Surgically modifying the appearance of the breast

Mammaplasty refers to a group of surgical procedures, the goal of which is to reshape or otherwise modify the appearance of the breast. There are two main types of mammoplasty:

  1. Augmentation mammaplasty is commonly performed to increase the size, change the shape, and/or alter the texture of the breasts. This usually involves the surgical implantation of breast implant devices.
  2. Reduction mammaplasty is commonly performed to reduce the size, change the shape, and/or alter the texture of the breasts. This involves the removal of breast tissue.
<span class="mw-page-title-main">Geoffrey Keynes</span> English surgeon and bibliophile (1887–1982)

Sir Geoffrey Langdon Keynes was a British surgeon and author. He began his career as a physician in World War I, before becoming a doctor at St Bartholomew's Hospital in London, where he made notable innovations in the fields of blood transfusion and breast cancer surgery. Keynes was also a publishing scholar and bibliographer of English literature and English medical history, focusing primarily on William Blake and William Harvey.

Surgical oncology is the branch of surgery applied to oncology; it focuses on the surgical management of tumors, especially cancerous tumors.

<span class="mw-page-title-main">Breast implant</span> Prosthesis used to change the size, shape, and contour of a persons breast

A breast implant is a prosthesis used to change the size, shape, and contour of a person's breast. In reconstructive plastic surgery, breast implants can be placed to restore a natural looking breast following a mastectomy, to correct congenital defects and deformities of the chest wall or, cosmetically, to enlarge the appearance of the breast through breast augmentation surgery.

<span class="mw-page-title-main">Umberto Veronesi</span> Italian oncologist, physician, scientist, and politician (1925–2016)

Umberto Veronesi was an Italian oncologist, physician, scientist and politician, internationally known for his contributions on prevention and treatment of breast cancer throughout a career spanning over fifty years.

<span class="mw-page-title-main">Bernard Fisher (scientist)</span> American biologist

Bernard Fisher was an American surgeon and a pioneer in the biology and treatment of breast cancer. He was a native of Pittsburgh. He was Chairman of the National Surgical Adjuvant Breast Project at the University of Pittsburgh School of Medicine. His work established definitively that early-stage breast cancer could be more effectively treated by lumpectomy, in combination with radiation therapy, chemotherapy, and/or hormonal therapy, than by radical mastectomy.

<span class="mw-page-title-main">George Beatson</span> British physician

Colonel Sir George Thomas Beatson was a British physician. He was a pioneer in the field of oncology, developing a new treatment for breast cancer, and has been called "the father of endocrine ablation in cancer management." The Beatson West of Scotland Cancer Centre and the Cancer Research UK Beatson Institute are named for him.

Sir Bruce Anthony John Ponder FMedSci FAACR FRS FRCP is an English geneticist and cancer researcher. He is Emeritus Professor of Oncology at the University of Cambridge and former director of the Cancer Research UK Cambridge Institute and of the Cancer Research UK Cambridge Cancer Centre.

Jan Měšťák(born August 26, 1944) is a Czech physician specializing in plastic surgery, university lecturer, head of the Department of Plastic Surgery at the First Faculty of Medicine of Charles University and University Hospital Bulovka in Prague and its founder.

Gregory Bruce Mann is an Australian surgical oncologist.

A preventive mastectomy or prophylactic mastectomy or risk-reducing mastectomy (RRM) is an elective operation to remove the breasts so that the risk of breast cancer is reduced.

<span class="mw-page-title-main">Krystal Barter</span>

Krystal Barter is a health activist, author and founder of Humanise Health, A patient-led & advocacy agency working with leading businesses in the health sector who make it their purpose to positively impact lives.

Kristi Funk is an American breast cancer surgeon known for her surgical treatment of celebrities Angelina Jolie and Sheryl Crow and her advocacy of whole-food plant-based nutrition.

Lisa Lynch was a British journalist, known for writing about her experience of having cancer on her blog, Alright Tit, and in a book, The C-Word. She was portrayed by Sheridan Smith in the 90-minute BBC television drama, The C-Word, written by Nicole Taylor and directed by Tim Kirkby.

Christobel Mary Saunders is a British-Australian oncologist and breast cancer specialist, who holds the position of Winthrop Professor of Surgical Oncology at the University of Western Australia.

<span class="mw-page-title-main">Nancy Baxter</span> Canadian surgeon and researcher

Nancy Baxter is a Canadian surgeon who is a professor and the Head of Melbourne University's School of Population and Global Health, while continuing to maintain her appointment as Professor of Surgery in the Department of Surgery and the Institute of Health Policy, Management and Evaluation at the University of Toronto. She is a scientist with the Li Ka Shing Knowledge Institute and is a senior scientist in the Cancer Theme Group with the Institute for Clinical Evaluative Sciences (ICES). Baxter has board certifications through the American Board of Surgery (2000) and the American Board of Colon and Rectal Surgery (2002). She is a Fellow of the American College of Surgeons, the Royal College of Physicians and Surgeons of Canada, and the American Society of Clinical Oncology.

Prevent Breast Cancer is a UK charity funding research solely aimed at preventing breast cancer. The Manchester-based charity aims to promote early diagnosis of breast cancer, improve cancer screenings, and change the habits and lifestyles of high-risk patients. Based at The Nightingale Centre & Prevent Breast Cancer Research Centre in Wythenshawe, Manchester, where the NHS co-ordinates the breast-screening programme for the Greater Manchester area.

<span class="mw-page-title-main">Jayant S. Vaidya</span> British-Indian surgeon and oncologist

Jayant S. Vaidya is a British-Indian surgeon-oncologist and clinical academic who, together with Michael Baum and Jeffrey Tobias, developed the technique called targeted intra-operative radiotherapy (TARGIT). He is a professor of surgery and oncology at the University College London, London and the author of two books on breast cancer, one on tobacco eradication, and over 200 academic articles.

Lisa J. M. Caldon is a British professor and clinical lecturer specialising in oncology. In her 20 year career, Caldon has published some 20 papers in the field of medicine. These have appeared in some of the top medical and peer-reviewed journals in Britain and abroad, including Medical Education, the European Journal of Cancer, the British Journal of Surgery, Patient Education and Counseling, Psycho-Oncology, Future Oncology, BMC Medical Informatics and Decision Making, and The Lancet Oncology. Caldon has worked at The University of Sheffield and with Cancer Research UK.

References

  1. "Breast Cancer Hope". Breast Cancer Hope. Archived from the original on 3 March 2016. Retrieved 22 October 2011.
  2. "Prof Kefah Mokbel breast disease the Princess Grace Hospital - Tatler". Archived from the original on 4 May 2014.
  3. "Archived copy" (PDF). Archived from the original (PDF) on 2 July 2017. Retrieved 4 December 2010.{{cite web}}: CS1 maint: archived copy as title (link)
  4. "Kefah Mokbel". www.brunel.ac.uk. Archived from the original on 11 October 2008.
  5. "Health4London". Health4London. Archived from the original on 11 March 2012. Retrieved 22 October 2011.
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  7. ""Mokbel K" – PubMed – NCBI". Ncbi.nlm.nih.gov. 3 October 2011. Retrieved 22 October 2011.
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  9. Al Sarakbi, W (2009). "The mRNA expression of SETD2 in human breast cancer: correlation with clinico-pathological parameters". BMC Cancer. 9 (1): 290. doi: 10.1186/1471-2407-9-290 . PMC   3087337 . PMID   19698110.
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  11. "World Journal of Surgical Procedures" (PDF). Retrieved 22 January 2013.
  12. "International Journal of Surgical Oncology – An Open Access Journal". Hindawi.com. Retrieved 22 October 2011.
  13. "CMRO Current Medical Research & Opinion Sample – C Volume 25 – V1". Content.yudu.com. Retrieved 22 October 2011.
  14. "Global Library of Women's Medicine". Glowm.com. Retrieved 22 October 2011.
  15. Gera, Ritika; Mokbel, Ramia; Igor, Ivanna; Mokbel, Kefah (February 2018). "Does the Use of Hair Dyes Increase the Risk of Developing Breast Cancer? A Meta-analysis and Review of the Literature". Anticancer Research. 38 (2): 707–716. doi: 10.21873/anticanres.13028 . PMID   30504369. S2CID   54484625.
  16. Gera, Ritika; Tayeh, Salim; Chehade, Hiba EL-Hage; Mokbel, Kefah (2018). "Does Transdermal Testosterone Increase the Risk of Developing Breast Cancer? A Systematic Review". Anticancer Research. 38 (12): 6615–6620. doi: 10.21873/anticanres.13028 . PMID   30504369.
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  24. "Express.co.uk – Home of the Daily and Sunday Express | UK News :: NHS under fire on digital breast tests". Dailyexpress.co.uk. 10 October 2010. Retrieved 22 October 2011.
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  26. "The Angelina Jolie Effect: Surge in Women Patients Requesting Double Mastectomies, Even when They Don't Carry BRCA1 Gene". 3 October 2013.
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