Knipholone

Last updated
Knipholone
Knipholone.svg
Atropisomerism of knipholone
Names
Preferred IUPAC name
1-(3-Acetyl-2,6-dihydroxy-4-methoxyphenyl)-4,5-dihydroxy-2-methylanthracene-9,10-dione
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
KEGG
PubChem CID
  • InChI=1S/C24H18O8/c1-9-7-13(27)20-21(22(29)11-5-4-6-12(26)18(11)24(20)31)16(9)19-14(28)8-15(32-3)17(10(2)25)23(19)30/h4-8,26-28,30H,1-3H3
    Key: DUENHQWYLVQDQK-UHFFFAOYSA-N
  • InChI=1/C24H18O8/c1-9-7-13(27)20-21(22(29)11-5-4-6-12(26)18(11)24(20)31)16(9)19-14(28)8-15(32-3)17(10(2)25)23(19)30/h4-8,26-28,30H,1-3H3
    Key: DUENHQWYLVQDQK-UHFFFAOYAR
  • COc1cc(O)c(c(O)c1C(C)=O)-c1c(C)cc(O)c2C(=O)c3c(O)cccc3C(=O)c12
Properties
C25H20O8
Molar mass 448.42 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Knipholone is a chemical compound found in the roots of Kniphofia foliosa of the family Asphodelaceae. [1] [2]

References

  1. ↑ Dagne, Ermias; Steglich, Wolfgang (1984-01-01). "Knipholone: a unique anthraquinone derivative from Kniphofia foliosa" . Phytochemistry. 23 (8): 1729–1731. doi:10.1016/S0031-9422(00)83479-2. ISSN   0031-9422.
  2. ↑ Wube, A. A.; Bucar, F.; Asres, K.; Gibbons, S.; Adams, M.; Streit, B.; Bodensieck, A.; Bauer, R. (2005-09-19). "Knipholone, a selective inhibitor of leukotriene metabolism". Phytomedicine: International Journal of Phytotherapy and Phytopharmacology. 13 (6): 452–456. doi:10.1016/j.phymed.2005.01.012. ISSN   0944-7113. PMID   16716917.
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