Ligatin, otherwise known as eIF2D, is a protein that in humans is encoded by the LGTN gene. [5] [6] This protein is not a component of the heterotrimeric eIF2 complex, but instead functions in different pathways of eukaryotic translation.
This gene encodes a protein receptor that localizes phosphoglycoproteins within endosomes and at the cell periphery. This trafficking receptor for phosphoglycoproteins may play a role in neuroplasticity by modulating cell-cell interactions, intracellular adhesion, and protein binding at membrane surfaces. In hippocampal neurons, long-lasting down-regulation of ligation mRNA levels occurs via post-transcriptional RNA processing following glutamate receptor activation. This protein contains single PUA and SUI1 domains and these domains may function in RNA binding and translation initiation, respectively. [6]
Lamin-B receptor is a protein, and in humans, it is encoded by the LBR gene.
Eukaryotic translation initiation factor 5A-1 is a protein that in humans is encoded by the EIF5A gene.
Peroxisomal targeting signal 1 receptor (PTS1R) is a protein that in humans is encoded by the PEX5 gene.
C-C chemokine receptor type 11 is a protein that in humans is encoded by the CCRL1 gene.
Folate receptor 1 is a protein that in humans is encoded by the FOLR1 gene.
B-cell receptor-associated protein 31 is a protein that in humans is encoded by the BCAP31 gene.
60S ribosomal protein L10 is a protein that in humans is encoded by the RPL10 gene.
Dynactin subunit 2 is a protein that in humans is encoded by the DCTN2 gene
Interleukin enhancer-binding factor 2 is a protein that in humans is encoded by the ILF2 gene.
Lysine-specific demethylase 5A is an enzyme that in humans is encoded by the KDM5A gene.
Eukaryotic translation initiation factor 4B is a protein that in humans is encoded by the EIF4B gene.
Cytoskeleton-associated protein 4 is a protein that in humans is encoded by the CKAP4 gene.
Folate receptor beta is a protein that in humans is encoded by the FOLR2 gene.
Mitochondrial import receptor subunit TOM22 homolog is a protein that in humans is encoded by the TOMM22 gene.
Translocon-associated protein subunit alpha is a protein that in humans is encoded by the SSR1 gene.
Progesterone receptor membrane component 1 is a protein which co-purifies with progesterone binding proteins in the liver and ovary. In humans, the PGRMC1 protein is encoded by the PGRMC1 gene.
Golgi reassembly-stacking protein of 55 kDa (GRASP55) also known as golgi reassembly-stacking protein 2 (GORASP2) is a protein that in humans is encoded by the GORASP2 gene. It was identified by its homology with GRASP65 and the protein's amino acid sequence was determined by analysis of a molecular clone of its complementary DNA. The first (N-terminus) 212 amino acid residues of GRASP55 are highly homologous to those of GRASP65, but the remainder of the 454 amino acid residues are highly diverged from GRASP65. The conserved region is known as the GRASP domain, and it is conserved among GRASPs of a wide variety of eukaryotes, but not plants. The C-terminus portion of the molecule is called the SPR domain. GRASP55 is more closely related to homologues in other species, suggesting that GRASP55 is ancestral to GRASP65. GRASP55 is found associated with the medial and trans cisternae of the Golgi apparatus.
Translocon-associated protein subunit beta also known as TRAP-beta is a protein that in humans is encoded by the SSR2 gene.
Golgin-45 is a protein that in humans is encoded by the BLZF1 gene.
Receptor expression-enhancing protein 2 is a protein that in humans is encoded by the REEP2 gene.