LUC7L

LUC7L
Identifiers
Aliases	LUC7L , LUC7-LIKE, LUC7B1, Luc7, SR+89, hLuc7B1, LUC7 like
External IDs	OMIM: 607782 MGI: 1914228 HomoloGene: 100558 GeneCards: LUC7L
Gene location (Human)
Chr.	Chromosome 16 (human)
End	229,463 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	26,504,478 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; anterior pituitary; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; cerebellar hemisphere; ; right uterine tube; ; canal of the cervix; ; body of pancreas; ; ganglionic eminence; ; left uterine tube;
	Top expressed in
	abdominal wall; ; medullary collecting duct; ; facial motor nucleus; ; morula; ; ventromedial nucleus; ; substantia nigra; ; maxillary prominence; ; arcuate nucleus; ; neural tube; ; lens;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RS domain binding ; protein binding ; mRNA binding ; identical protein binding ;
Cellular component	U1 snRNP ; U2-type prespliceosome ; nucleus ;
Biological process	mRNA splice site selection ; negative regulation of striated muscle tissue development ;
	Sources:Amigo / QuickGO
Orthologs
	55692
	66978
	ENSG00000007392
	ENSMUSG00000024188
	Q9NQ29 ; Q1W6G4
	Q9CYI4
	NM_018032 ; NM_201412 ; NM_001320226 ; NM_001330420
	NM_025881 ; NM_028190
NP_001307155 ; NP_001317349 ; NP_060502 ; NP_958815 ; NP_060502.1 ;
	NP_001307155.1
	NP_080157 ; NP_082466
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated January 14, 2024

Putative RNA-binding protein Luc7-like 1 is a protein that in humans is encoded by the LUC7L gene.^[5]

The LUC7L gene may represent a mammalian heterochromatic gene, encoding a putative RNA-binding protein similar to the yeast Luc7p subunit of the U1 snRNP splicing complex that is normally required for 5-prime splice site selection.^[5]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000007392 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024188 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 "Entrez Gene: LUC7L LUC7-like (S. cerevisiae)".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Daniels RJ, Peden JF, Lloyd C, et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16". Hum. Mol. Genet. 10 (4): 339–52. doi: 10.1093/hmg/10.4.339 . PMID 11157797.
Tufarelli C, Frischauf AM, Hardison R, et al. (2001). "Characterization of a widely expressed gene (LUC7-LIKE; LUC7L) defining the centromeric boundary of the human alpha-globin domain". Genomics. 71 (3): 307–14. doi:10.1006/geno.2000.6394. PMID 11170747.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Goehler H, Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi: 10.1016/j.molcel.2004.09.016 . PMID 15383276.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID 17081983. S2CID 7827573.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948 . PMID 17353931.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000007392 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024188 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] 1 2 "Entrez Gene: LUC7L LUC7-like (S. cerevisiae)".

[1]

[2]

[3]

[4]

[5]

LUC7L

Related Research Articles

References

Further reading