LUC7L2

LUC7L2
Identifiers
Aliases	LUC7L2 , CGI-74, LUC7B2, CGI-59, LUC7-like 2 pre-mRNA splicing factor, LUC7 like 2, pre-mRNA splicing factor
External IDs	OMIM: 613056; MGI: 2183260; HomoloGene: 56737; GeneCards: LUC7L2; OMA:LUC7L2 - orthologs
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7q34 Start 139,340,359 bp [1] End 139,423,457 bp [1]
Gene location (Mouse) Chr. Chromosome 6 (mouse) [2] Band 6|6 B1 Start 38,551,334 bp [2] End 38,609,470 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve left lobe of thyroid gland right lobe of thyroid gland right uterine tube gastric mucosa Achilles tendon canal of the cervix ventricular zone left uterine tube Descending thoracic aorta Top expressed in mammillary body ventromedial nucleus lateral septal nucleus body of femur aortic valve anterior amygdaloid area cerebellar vermis lateral geniculate nucleus ascending aorta lobe of cerebellum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function enzyme binding protein binding mRNA binding RNA binding Cellular component U1 snRNP nuclear speck U2-type prespliceosome nucleus nucleoplasm Biological process mRNA splice site selection Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51631 192196 Ensembl ENSG00000146963 ENSMUSG00000029823 UniProt Q9Y383 Q7TNC4 RefSeq (mRNA) NM_016019 NM_001244585 NM_001270643 NM_001170848 NM_001170849 NM_138680 NM_001311099 NM_001311100 NM_001331222 NM_001331223 RefSeq (protein) NP_001231514 NP_001257572 NP_057103 NP_001164319 NP_001164320 NP_001298028 NP_001298029 NP_001318151 NP_001318152 NP_619621 Location (UCSC) Chr 7: 139.34 – 139.42 Mb Chr 6: 38.55 – 38.61 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Putative RNA-binding protein Luc7-like 2 is a protein that in humans is encoded by the LUC7L2 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000146963 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000029823 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC   310876 . PMID   10810093.
6. "Entrez Gene: LUC7L2 LUC7-like 2 (S. cerevisiae)".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi: 10.1038/nature01782 . PMID   12853948.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC   442148 . PMID   15231748.
• Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. Bibcode:2004CBio...14.1436J. doi: 10.1016/j.cub.2004.07.051 . PMID   15324660. S2CID   2371325.
• Goehler H, Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi: 10.1016/j.molcel.2004.09.016 . PMID   15383276.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID   15635413. S2CID   4344740.
• Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl: 11858/00-001M-0000-0010-8592-0 . PMID   16169070. S2CID   8235923.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.