Laparoscopic radical prostatectomy

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Laparoscopic radical prostatectomy
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Laparoscopic radical prostatectomy (LRP) is a form of radical prostatectomy, an operation for prostate cancer. Contrasted with the original open form of the surgery, it does not make a large incision but instead uses fiber optics and miniaturization.[ citation needed ]

Contents

The laparoscopic and open forms of radical prostatectomy physically remove the entire prostate and reconstruct the urethra directly to the bladder. Laparoscopic radical prostatectomy and open radical prostatectomy differ in how they access the deep pelvis and generate operative views. In contrast to open radical prostatectomy, the laparoscopic radical prostatectomy makes no use of retractors and does not require that the abdominal wall be parted and stretched for the duration of the operation.

Medical uses

A few good studies exist looking at open versus laparoscopic versus laparoscopic and robotic radical prostatectomy in cancer as of 2011. [1]

There is a robotic and non robotic version. [2] These two versions have unclear differences in cancer related outcomes [2]

The American Cancer Society states that success with laparoscopic technique is determined by surgeon experience and focus. There is a long learning curve for the robotic procedure. It is estimated that about 60 cases need to be performed by a surgeon to be comfortable with the procedure and about 250 cases to be an expert.

The procedure takes at least five hours and as long as eight hours for the average urologist, without a bilateral lymph node dissection, compared to 2.5–3 hours when done by an open technique with an incision, with a completed lymph node dissection.

There is a greater risk of accidentally incising into the prostate, resulting in "margin positivity," i.e. leaving cancer within the patient, in otherwise organ confined disease, even in the hands of experts. This is presumed to happen as a result of the lack of tactile sensation. Margin positivity is strongly correlated with PSA recurrences and a fourfold annual increase in cancer recurrence compared to men with negative surgical margins. There was a recent study from the University of Michigan by Hollenbeck et al. (Urology 2007; 70: 96-100) after their first 200 cases that they were able to eliminate extensive positive margins (12% in their first 15 cases versus 2% after performing 81 cases) but they continued to have a positive surgical margin rate of 22%. Their conclusion was "It seems that cumulative surgeon volume beyond that which can be obtained in the typical urology practice may be needed to obtain ideal margin rates with this new technology."Patrick C. Walsh M.D in an editorial comment in the Journal of Urology, commenting on this article, compared his own experience at Johns Hopkins with organ confined disease with a positive surgical margin rate of only 1.8%.

Another problem in higher-risk cases is that many surgeons using the robotic technique do not perform a lymph node dissection, as it is difficult to perform this adequately, robotically. The rationale usually given is that patient selection is such that most patients with Gleason score 6 on pathology do not need a lymphadenectomy. However, a small number of patients with Gleason 6 adenocarcinoma of the prostate are upgraded to Gleason 7 on final pathology. Any micrometastases in lymph nodes would not be detected, not be removed and would increase the risk of recurrences.

There has not been any evidence in the urologic literature showing a benefit in regard to continence, potency or cure rates with the robotic procedure. Interest in the procedure is often patient driven, by patients who have been led to believe by the extensive advertising, that there are significant benefits to be obtained from the procedure. The open radical prostatectomy is still the "gold standard."[ citation needed ]

2008 studies

There was a study in the Journal of Clinical Oncology from Harvard [3] using a national random sample of Medicare patients, showing that patients who had a laparoscopic/robotic radical prostatectomy underwent hormonal therapy in more than 25% of cases after the procedure compared to an open radical prostatectomy [this is usually not necessary with open radical prostatectomy if all the cancer has been removed and is usually less than 10% of cases], with a high risk of secondary procedures for bladder neck contracture [40% greater risk] which can result in poorer continence.

In an accompanying editorial in the journal commenting on this article [4] (Note: over 9 years ago) Michael L.Blute, M.D. of the Mayo Clinic wrote that "Patient interest in robotic assisted radical prostatectomy has been the result of a highly successful marketing campaign with the resultant consumer demand. Patients have been led to believe that hospital and recovery times are shorter and outcomes are better, a study has shown this expectation not to be the case." He also wrote "Currently, open technique is the state-of-the-art procedure in experienced hands, as the long-term results for laparoscopic/robotic assisted radical prostatectomy do not exist. The published literature fails to answer the question whether these procedures meet 'quality standards.

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Mani Menon

Mani Menon, born 9 July 1948 in Trichur, India, is an American surgeon whose pioneering work has helped to lay the foundation for modern robotic cancer surgery. He is the founding director and the Raj and Padma Vattikuti Distinguished Chair of the Vattikuti Urology Institute at the Henry Ford Hospital in Detroit, MI, where he established the first cancer-oriented robotics program in the world. Menon is widely regarded for his role in the development of robotic surgery techniques for the treatment of patients with prostate, kidney, and bladder cancers, as well as for the development of robotic kidney transplantation.
Menon is the recipient of the Gold Cystoscope award, Hugh Hampton Young award, the Keyes Medal, the prestigious B.C. Roy award.

Ashutosh Tewari American urologist, oncologist

Ashutosh K. Tewari is the chairman of urology at the Icahn School of Medicine at Mount Sinai Hospital in New York City. He is a board certified American urologist, oncologist, and principal investigator. Before moving to the Icahn School of Medicine in 2013, he was the founding director of both the Center for Prostate Cancer at Weill Cornell Medical College and the LeFrak Center for Robotic Surgery at NewYork–Presbyterian Hospital. Dr. Tewari was the Ronald P. Lynch endowed Chair of Urologic Oncology and the hospital's Director of Robotic Prostatectomy, treating patients with prostate, urinary bladder and other urological cancers. He is the current President of the Society for Urologic Robotic Surgeons (SURS) and the Committee Chair of the Prostate Program. Dr. Tewari is a world leading urological surgeon, and has performed over 9,000 robotically assisted procedures using the da Vinci Surgical System. Academically, he is recognized as a world-renowned expert on urologic oncology with over 250 peer reviewed published papers to his credit; he is on such lists as America's Top Doctors, New York Magazine's Best Doctors, and Who's Who in the World. In 2012, he was given the American Urological Association Gold Cystoscope Award for "outstanding contributions to the field of urologic oncology, most notably the treatment of prostate cancer and the development of novel techniques to improve the outcomes of robotic prostatectomy."

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Michael Palese

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Roger Kirby

Roger Sinclair Kirby FRCS(Urol), FEBU is a British retired prostate surgeon and professor of urology, researcher, writer on men's health and prostate disease, founding editor of the journal Prostate Cancer and Prostatic Diseases and Trends in Urology and Men's Health and a fundraiser for prostate disease charities, best known for his use of the da Vinci surgical robot for laparoscopic prostatectomy in the treatment of prostate cancer. He is a co-founder and president of the charity The Urology Foundation (TUF), vice-president of the charity Prostate Cancer UK, trustee of the King Edward VII's Hospital and as of 2020 is president of the Royal Society of Medicine (RSM), London.

Mark S. Soloway is a leading authority in urologic cancer, researcher, former departmental Chair, medical professor and invitational lecturer. He served as Chairman of the University of Miami Miller School of Medicine Department of Urology and is currently a Professor at the Miller School of Medicine. Born in Cleveland, Soloway received his B.S. from Northwestern University in Chicago, Il (1961–1964) and completed his M.D. and residency at Case Western Reserve University School of Medicine in Cleveland, Ohio (1964–1970). He completed a fellowship at the National Cancer Institute of the National Institute of Health in Bethesda, MD (1970–1972). Soloway has received numerous awards for his work as a researcher and teacher, including the American Urological Association's Gold Cystoscope Award “For the individual who has contributed most to the field of urology within ten years of completion of his residency program” (1984), Mosby Scholarship for Scholastic Excellence (1967), North Central Section of American Urological Association Traveling Fellowship Award (1972) and many others.

Michael Stifelman

Michael D. Stifelman, M.D.,, an internationally recognized American physician and urologist, is known for his work in upper tract urinary reconstructive surgery and use of multi- and single-port robotic surgical technology to perform complex cancer and non-cancer urological procedures. An innovator in the field of urological surgery, Dr. Stifelman leads a renowned Center of Excellence for robotic surgery at Hackensack University Medical Center in Hackensack, New Jersey, and serves as chair of the hospital’s Department of Urology.

Vipul Patel

Vipul R. Patel, FACS is the founder and Medical Director of the Florida Hospital Global Robotics Institute, founder and Vice President of the Society of Robotic Surgery, and founder and Editor Emeritus of The Journal of Robotic Surgery. He is board certified by the American Urological Association and specializes in robotic surgery for prostate cancer. As of February, 2018 he performed his 11,000th robotic-assisted prostatectomy. The large volume of prostatectomies he has performed has enabled him to amass a large amount of statistical evidence regarding the efficacy of robotic techniques which has been used in developing and refining techniques. Patel credits the use of robotic assisted surgery with helping surgeons achieve better surgical outcomes with the "trifecta" of cancer control, continence and sexual function. In the course of his career Patel has led and participated in studies that have resulted in developing improved outcomes for robotic surgery and urologic treatment.

References

  1. Heer, R; Raymond, I; Jackson, MJ; Soomro, NA (September 2011). "A critical systematic review of recent clinical trials comparing open retropubic, laparoscopic and robot-assisted laparoscopic radical prostatectomy". Reviews on Recent Clinical Trials. 6 (3): 241–9. doi:10.2174/157488711796575513. PMID   21682688.
  2. 1 2 Huang, X; Wang, L; Zheng, X; Wang, X (March 2017). "Comparison of perioperative, functional, and oncologic outcomes between standard laparoscopic and robotic-assisted radical prostatectomy: a systemic review and meta-analysis". Surgical Endoscopy. 31 (3): 1045–1060. doi:10.1007/s00464-016-5125-1. PMID   27444830. S2CID   2670881.
  3. "Utilization and Outcomes of Minimally Invasive Radical Prostatectomy." Jim C.Hu et al. Volume 26. Number 14. May 10, 2008. Page 2278-2284
  4. "Radical Prostatectomy by Open or Laparoscopic/Robotic Techniques: an Issue of Surgical Device or Surgical Expertise?" Journal of Clinical Oncology. Volume 26. Number 14. May 10, 2008. Page 2248-2249