Laura Boykin

Last updated
Laura Boykin
Dr. Laura M. Boykin.jpg
Alma mater Occidental College
San Francisco State University
University of New Mexico
Awards TED fellow (2017)
Scientific career
Institutions University of Western Australia
United States Department of Agriculture

Laura Boykin is an American computational biologist who uses supercomputing and genomics to help farmers in Sub-Saharan Africa. She has studied the evolution of the agricultural pest whitefly and identified genetic differences between various species. She works with African scientists to develop computing and genomics skills across the continent, and is a Senior TED fellow.

Contents

Early life and education

Boykin grew up with her mother, who worked at Phoenix Suns basketball games to pay Boykin's way through college. [1] She studied biology at Occidental College, where she worked on the chaparral shrub Arctostaphylos parryana . She moved to San Francisco State University for her Master's studies, working with Bob Patterson on a phylogenetic analysis of Arctostaphylos. She earned her PhD in 2003 at the University of New Mexico, where she worked in the Los Alamos National Laboratory theoretical biology research group. [1] Here she learned how to use a supercomputer, analysing sequence data of influenza and hepatitis C in an effort to provide information for Centers for Disease Control and Prevention (CDC) vaccines. [1] Boykin moved to the United States Department of Agriculture in Florida, where she began to investigate whiteflies. At the time, Europe limited the importation of flowers from Florida because of concerns about whiteflies. [1] After completing her postdoctoral research, Boykin taught science at Jensen Beach High School. [2] In 2009 Boykin moved to Lincoln University, where she worked in the Bio-Protection Research Centre.

Research and career

Since 2012, Boykin has been a senior researcher in the Australian Research Council Plant Energy Biology group at the University of Western Australia. [3] She became interested in Africa as whiteflies native to the continent represent the base of their evolutionary tree, and after attending a Bill & Melinda Gates Foundation workshop that visited a smallholding farm in Kenya seriously impacted by them. [1] [4] She works with African researchers to use genomics and supercomputers to improve their ability to understand and tackle insect outbreaks. [1] The portable DNA sequencing devices that she introduced to Africa have been helping fight crop disease since 2017. [5] [6] [7] [8]

In an effort to establish the causes of the devastation of cassava crops, Boykin investigates the various whitefly in Sub-Saharan Africa. Worldwide, over 700 million people a day depend on cassava for their daily calories. [1] Whiteflies transmit two viruses that are lethal for cassava; the cassava mosaic virus and cassava brown streak virus disease. These viruses are contained in Tanzania, Uganda, Malawi, Zimbabwe and Mozambique. [1] In particular, Boykin is interested in the Bemisia tabaci (silverleaf whitefly), which plague East Africa. [1] She works with the Mikocheni Agricultural Research Institute (Tanzania), the Department of Agricultural Research & Technical Services (Malawi) and the National Crops Resources Research Institute (Uganda) in the Cassava Virus Action Project (CVAP). [9] Boykin works directly with Joseph Ndunguru, an African scientist who has brought biotechnology to Africa. [1] CVAP used the Pawsey Supercomputing Centre to identify that the whitefly is actually a species complex of over 34 different species. [10] The work of Boykin and her Cassava warriors has resulted in a yield increase of over 800% for the cassava plant. [11] Boykin created WhiteFlyBase, a space to share data about whitefly species. [12]

Boykin was appointed a Senior TED fellow in 2017. [1] She delivered her first TED Talk, Why Cassava is a Poverty Fighter, in Perth in 2016, but has also appeared on the main TED stage discussing the African Cassava Whitefly Project in Vancouver. [13] [14] She was made a Gifted Citizen in 2017. [15] She was part of Science Foo Camp in 2019. [16]

Related Research Articles

<span class="mw-page-title-main">Cassava</span> Species of flowering plant in the spurge family Euphorbiaceae

Manihot esculenta, commonly called cassava, manioc, or yuca, is a woody shrub of the spurge family, Euphorbiaceae, native to South America. Although a perennial plant, cassava is extensively cultivated as an annual crop in tropical and subtropical regions for its edible starchy tuberous root, a major source of carbohydrates. Though it is often called yuca in parts of Spanish America and in the United States, it is not related to yucca, a shrub in the family Asparagaceae. Cassava is predominantly consumed in boiled form, but substantial quantities are used to extract cassava starch, called tapioca, which is used for food, animal feed, and industrial purposes. The Brazilian farinha, and the related garri of West Africa, is an edible coarse flour obtained by grating cassava roots, pressing moisture off the obtained grated pulp, and finally drying it.

Agricultural biotechnology, also known as agritech, is an area of agricultural science involving the use of scientific tools and techniques, including genetic engineering, molecular markers, molecular diagnostics, vaccines, and tissue culture, to modify living organisms: plants, animals, and microorganisms. Crop biotechnology is one aspect of agricultural biotechnology which has been greatly developed upon in recent times. Desired trait are exported from a particular species of Crop to an entirely different species. These transgene crops possess desirable characteristics in terms of flavor, color of flowers, growth rate, size of harvested products and resistance to diseases and pests.

<span class="mw-page-title-main">Whitefly</span> Family of insects

Whiteflies are Hemipterans that typically feed on the undersides of plant leaves. They comprise the family Aleyrodidae, the only family in the superfamily Aleyrodoidea. More than 1550 species have been described.

<span class="mw-page-title-main">Molecular genetics</span> Scientific study of genes at the molecular level

Molecular genetics is a sub-field of biology that addresses how differences in the structures or expression of DNA molecules manifests as variation among organisms. Molecular genetics often applies an "investigative approach" to determine the structure and/or function of genes in an organism's genome using genetic screens. The field of study is based on the merging of several sub-fields in biology: classical Mendelian inheritance, cellular biology, molecular biology, biochemistry, and biotechnology. Researchers search for mutations in a gene or induce mutations in a gene to link a gene sequence to a specific phenotype. Molecular genetics is a powerful methodology for linking mutations to genetic conditions that may aid the search for treatments/cures for various genetics diseases.

<span class="mw-page-title-main">Psyllidae</span> Family of true bugs

Psyllidae, the jumping plant lice or psyllids, are a family of small plant-feeding insects that tend to be very host-specific, i.e. each plant-louse species only feeds on one plant species (monophagous) or feeds on a few closely related plants (oligophagous). Together with aphids, phylloxerans, scale insects and whiteflies, they form the group called Sternorrhyncha, which is considered to be the most "primitive" group within the true bugs (Hemiptera). They have traditionally been considered a single family, Psyllidae, but recent classifications divide the group into a total of seven families; the present restricted definition still includes more than 70 genera in the Psyllidae. Psyllid fossils have been found from the Early Permian before the flowering plants evolved. The explosive diversification of the flowering plants in the Cretaceous was paralleled by a massive diversification of associated insects, and many of the morphological and metabolic characters that the flowering plants exhibit may have evolved as defenses against herbivorous insects.

<span class="mw-page-title-main">Silverleaf whitefly</span> Species of true bug

The silverleaf whitefly is one of several species of whitefly that are currently important agricultural pests. A review in 2011 concluded that the silverleaf whitefly is actually a species complex containing at least 40 morphologically indistinguishable species.

Genotyping is the process of determining differences in the genetic make-up (genotype) of an individual by examining the individual's DNA sequence using biological assays and comparing it to another individual's sequence or a reference sequence. It reveals the alleles an individual has inherited from their parents. Traditionally genotyping is the use of DNA sequences to define biological populations by use of molecular tools. It does not usually involve defining the genes of an individual.

<i>Begomovirus</i> Genus of viruses

Begomovirus is a genus of viruses, in the family Geminiviridae. They are plant viruses that as a group have a very wide host range, infecting dicotyledonous plants. Worldwide they are responsible for a considerable amount of economic damage to many important crops such as tomatoes, beans, squash, cassava and cotton. There are 445 species in this genus.

<span class="mw-page-title-main">Cassava mosaic virus</span> Genus of viruses

Cassava mosaic virus is the common name used to refer to any of eleven different species of plant pathogenic virus in the genus Begomovirus. African cassava mosaic virus (ACMV), East African cassava mosaic virus (EACMV), and South African cassava mosaic virus (SACMV) are distinct species of circular single-stranded DNA viruses which are transmitted by whiteflies and primarily infect cassava plants; these have thus far only been reported from Africa. Related species of viruses are found in India and neighbouring islands, though cassava is cultivated in Latin America as well as Southeast Asia. Nine species of cassava-infecting geminiviruses have been identified between Africa and India based on genomic sequencing and phylogenetic analysis. This number is likely to grow due to a high rate of natural transformation associated with CMV.

Cotton leaf curl viruses (CLCuV) are a number of plant pathogenic virus species of the family Geminiviridae.

Indian cassava mosaic virus(ICMV) is a plant pathogenic virus of the family Geminiviridae. It affects cassava in India and certain other countries. It is considered to be an invasive species.

Tomato yellow leaf curl virus (TYLCV) is a DNA virus from the genus Begomovirus and the family Geminiviridae. TYLCV causes the most destructive disease of tomato, and it can be found in tropical and subtropical regions causing severe economic losses. This virus is transmitted by an insect vector from the family Aleyrodidae and order Hemiptera, the whitefly Bemisia tabaci, commonly known as the silverleaf whitefly or the sweet potato whitefly. The primary host for TYLCV is the tomato plant, and other plant hosts where TYLCV infection has been found include eggplants, potatoes, tobacco, beans, and peppers. Due to the rapid spread of TYLCV in the last few decades, there is an increased focus in research trying to understand and control this damaging pathogen. Some interesting findings include virus being sexually transmitted from infected males to non-infected females, and an evidence that TYLCV is transovarially transmitted to offspring for two generations.

Sweet potato mild mottle virus (SPMMV) is a plant pathogenic virus of the family Potyviridae.

<span class="mw-page-title-main">Fall armyworm</span> One of the worst farm pests, worldwide

The fall armyworm is a species in the order Lepidoptera and one of the species of the fall armyworm moths distinguished by their larval life stage. The term "armyworm" can refer to several species, often describing the large-scale invasive behavior of the species' larval stage. It is regarded as a pest and can damage and destroy a wide variety of crops, which causes large economic damage. Its scientific name derives from frugiperda, which is Latin for lost fruit, named because of the species' ability to destroy crops. Because of its propensity for destruction, the fall armyworm's habits and possibilities for crop protection have been studied in depth. It is also a notable case for studying sympatric speciation, as it appears to be diverging into two species currently. Another remarkable trait of the larva is that they consistently practice cannibalism, despite its fitness costs.

Crop diversity or crop biodiversity is the variety and variability of crops, plants used in agriculture, including their genetic and phenotypic characteristics. It is a subset of and a specific element of agricultural biodiversity. Over the past 50 years, there has been a major decline in two components of crop diversity; genetic diversity within each crop and the number of species commonly grown.

Cassava brown streak virus disease (CBSD) is a damaging disease of cassava plants, and is especially troublesome in East Africa. It was first identified in 1936 in Tanzania, and has spread to other coastal areas of East Africa, from Kenya to Mozambique. Recently, it was found that two distinct viruses are responsible for the disease: cassava brown streak virus (CBSV) and Ugandan cassava brown streak virus (UCBSV). Both have (+)ss RNA genomes, belong to the genus Ipomovirus in the family Potyviridae, and produce generally similar symptoms in infected plants. Root rot renders the cassava tuber inedible, resulting in severe loss of economic value; therefore, current research focuses on achieving cultivars that do not develop the necrotic rot. This disease is considered to be the biggest threat to food security in coastal East Africa and around the eastern lakes.

<span class="mw-page-title-main">Rajeev Kumar Varshney</span>

Rajeev Kumar Varshney is an agricultural scientist, specializing in genomics, genetics, molecular breeding and capacity building in developing countries. Varsheny is currently the Research Program Director- Genetic Gains that includes several units viz. Genomics & Trait Discovery, Forward Breeding, Pre-Breeding, Cell, Molecular Biology & Genetic Engineering, Seed Systems, Biotechnology- ESA, Sequencing and Informatics Services Unit, and Genebank ; and Director, Center of Excellence in Genomics & Systems Biology at the International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), a global agricultural research institute. He holds Adjunct/Honorary/Visiting Professor positions at 10 academic institutions in Australia, China, Ghana, Hong Kong and India, including Murdoch University, The University of Western Australia, University of Queensland, West Africa Centre for Crop Improvement, University of Hyderabad, Chaudhary Charan Singh University and Professor Jayashankar Telangana State Agricultural University.

Cassava brown streak virus is a species of positive-strand RNA viruses in the genus Ipomovirus and family Potyviridae which infects plants. Member viruses are unique in their induction of pinwheel, or scroll-shaped inclusion bodies in the cytoplasm of infected cells. Cylindrical inclusion bodies include aggregations of virus-encoded helicase proteins. These inclusion bodies are thought to be sites of viral replication and assembly, making then an important factor in the viral lifecycle. Viruses from both the species Cassava brown streak virus and Ugandan cassava brown streak virus (UCBSV), lead to the development of Cassava Brown Streak Disease (CBSD) within cassava plants.

<i>Sweet potato leaf curl virus</i> Species of virus

Sweet potato leaf curl virus is commonly abbreviated SPLCV. Select isolates are referred to as SPLCV followed by an abbreviation of where they were isolated. For example, the Brazilian isolate is referred to as SPLCV-Br.

Elijah Miinda Ateka is a Professor of Plant Virology at the Jomo Kenyatta University of Agriculture and Technology. He is involved with the diagnosis and characterisation of the sweet potato virus and the cassava virus, and is part of the Cassava Virus Action Project (CVAP).

References

  1. 1 2 3 4 5 6 7 8 9 10 11 "Avoiding the hunger season: How a TED Fellow is working to save African cassava from whiteflies". TED Blog. 2015-05-22. Retrieved 2019-07-15.
  2. "lauraboykin". Computational Biology for Sustainable Agriculture. Retrieved 2019-07-15.
  3. "Laura Boykin — the UWA Profiles and Research Repository". research-repository.uwa.edu.au. Retrieved 2019-07-15.
  4. "Fighting Famine in East Africa with HPC, Amazing Impact". www.cray.com. Retrieved 2019-07-15.
  5. "Portable DNA sequencers help African farmers fight crop disease". phys.org. Retrieved 2019-07-15.
  6. lauraboykin (2017-09-15). "New portable DNA sequencers help East African farmers fight crop disease". Cassava Virus Action Project. Retrieved 2019-07-15.
  7. "Portable DNA sequencers help African farmers fight crop disease". News | The University Of Western Australia. Retrieved 2019-07-15.
  8. "BBC World Service - Business Matters, New tech to help farmers in Africa predict disease". BBC. Retrieved 2019-07-15.
  9. Eng, Karen Frances (2017-09-21). "In East African cassava fields, a new genomics tool is saving crops and lives". Medium. Retrieved 2019-07-15.
  10. "Fighting Famine in East Africa with HPC, Amazing Impact". www.cray.com. Retrieved 2019-07-15.
  11. "Laura Boykin". Raising the bar. Retrieved 2019-07-15.
  12. "Whiteflybase 2.0". www.whiteflybase.org. Archived from the original on 2019-08-02. Retrieved 2019-07-15.
  13. TEDx Talks (2016-06-03), Why cassava is a poverty fighter | Laura Boykin | TEDxPerth , retrieved 2019-07-15
  14. "Laura and TED, engaging audiences across the world". www.cassavawhitefly.org. Retrieved 2019-07-15.
  15. "Speakers". londoncallingconf.co.uk. Retrieved 2019-07-15.
  16. "News". Computational Biology for Sustainable Agriculture. Retrieved 2019-07-15.