The state of South Carolina is divided into three geographically distinct numbering plan areas (NPAs) in the North American Numbering Plan (NANP), each served by an area code overlay of two area codes each.
| Area code | Year created | Parent NPA | Overlay | Numbering plan area |
|---|---|---|---|---|
| 803 | 1947 | – | 803/839 | Central South Carolina (Midlands), including Columbia |
| 839 | 2020 | 803 | ||
| 864 | 1995 | 803 | 821/864 | Northwest South Carolina (Upstate) |
| 821 | 2024 | 864 | ||
| 843 | 1998 | 803 | 843/854 | Eastern and coastal South Carolina (Lowcountry) |
| 854 | 2015 | 843 | ||