MAB21L2

MAB21L2
Identifiers
Aliases	MAB21L2 , MCOPS14, Mab-21-like 2 (C. elegans), mab-21 like 2, MCSKS14
External IDs	OMIM: 604357 MGI: 1346022 HomoloGene: 7824 GeneCards: MAB21L2
Gene location (Human)
Chr.	Chromosome 4 (human)
End	150,584,693 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	86,455,936 bp
RNA expression pattern
	Top expressed in
	pons; ; retinal pigment epithelium; ; synovial joint; ; superior vestibular nucleus; ; transverse colon; ; Achilles tendon; ; cecum; ; optic nerve; ; tibia; ; appendix;
	Top expressed in
	maxillary prominence; ; abdominal wall; ; superior cervical ganglion; ; hand; ; mirror; ; medial vestibular nucleus; ; iris; ; foot; ; pontine nuclei; ; secondary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding ;
Cellular component	nucleus ; cytoplasm ;
Biological process	eye development ; multicellular organism development ; camera-type eye development ; nervous system development ; positive regulation of cell population proliferation ; embryonic body morphogenesis ;
	Sources:Amigo / QuickGO
Orthologs
	10586
	23937
	ENSG00000181541
	ENSMUSG00000057777
	Q9Y586
	Q8BPP1
	NM_006439
	NM_011839
	NP_006430
	NP_035969
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Mab-21-like 2 (C. elegans) is a protein that in humans is encoded by the MAB21L2 gene.^[5]

Function

This gene is similar to the C. elegans MAB-21 cell fate-determining gene, a downstream target of transforming growth factor-beta signaling. It is thought that this gene may be involved in neural development. The protein encoded by this gene is primarily nuclear, although some cytoplasmic localization has been observed. [provided by RefSeq, Jul 2008].

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