An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the common cold or influenza; drugs which inhibit viruses are termed antiviral drugs or antivirals rather than antibiotics.
β-lactam antibiotics are antibiotics that contain a beta-lactam ring in their molecular structure. This includes penicillin derivatives (penams), cephalosporins and cephamycins (cephems), monobactams, carbapenems and carbacephems. Most β-lactam antibiotics work by inhibiting cell wall biosynthesis in the bacterial organism and are the most widely used group of antibiotics. Until 2003, when measured by sales, more than half of all commercially available antibiotics in use were β-lactam compounds. The first β-lactam antibiotic discovered, penicillin, was isolated from a rare variant of Penicillium notatum.
Pseudoalteromonas is a genus of marine bacteria. In 1995, Gauthier et al proposed Pseudoalteromonas as a new genus to be split from Alteromonas. The Pseudoalteromonas species that were described before 1995 were originally part of the genus Alteromonas, and were reassigned to Pseudoalteromonas based on their rRNA-DNA analysis.
Brazilian purpuric fever (BPF) is an illness of children caused by the bacterium Haemophilus influenzae biogroup aegyptius which is ultimately fatal due to sepsis. BPF was first recognized in the São Paulo state of Brazil in 1984. At this time, young children between the ages of 3 months and 10 years were contracting a strange illness which was characterized by high fever and purpuric lesions on the body. These cases were all fatal, and originally thought to be due to meningitis. It was not until the autopsies were conducted that the cause of these deaths was confirmed to be infection by H. influenzae aegyptius. Although BPF was thought to be confined to Brazil, other cases occurred in Australia and the United States during 1984–1990.
Pristinamycin (INN), also spelled pristinamycine, is an antibiotic used primarily in the treatment of staphylococcal infections, and to a lesser extent streptococcal infections. It is a streptogramin group antibiotic, similar to virginiamycin, derived from the bacterium Streptomyces pristinaespiralis. It is marketed in Europe by Sanofi-Aventis under the trade name Pyostacine.
In microbiology, the minimum inhibitory concentration (MIC) is the lowest concentration of a chemical, usually a drug, which prevents visible growth of a bacterium or bacteria. MIC depends on the microorganism, the affected human being, and the antibiotic itself. It is often expressed in micrograms per milliliter (μg/mL) or milligrams per liter (mg/L).
Colitose is a mannose-derived 3,6-dideoxysugar produced by certain bacteria. It is a constituent of the lipopolysaccharide.
Alteromonas is a genus of Proteobacteria found in sea water, either in the open ocean or in the coast. It is Gram-negative. Its cells are curved rods with a single polar flagellum.
Pseudoalteromonas carrageenovora is a marine bacterium. It belongs to the Gammaproteobacter. The cells are rod-shaped.
Antimicrobial pharmacodynamics is the relationship between the concentration of an antibiotic and its ability to inhibit vital processes of endo- or ectoparasites and microbial organisms. This branch of pharmacodynamics relates the concentration of an anti-infective agent to its effect, specifically to its antimicrobial effect.
Pseudoalteromonas phenolica is a marine bacterium species in the genus Pseudoalteromonas.
Desulfobacula phenolica is a bacterium species in the genus Desulfobacula.
MC21-B is an antibiotic isolated from the O-BC30T strain of a marine bacterium, Pseudoalteromonas phenolica. MC21-B is cytotoxic to human leukaemia cells and human normal dermal fibroblasts.
Pseudoalteromonas agarivorans is a marine bacterium.
Pseudoalteromonas antarctica is a marine bacterium isolated from Antarctic coastal marine environments.
Pseudoalteromonas aurantia is an antibacterial-producing marine bacterium commonly found in Mediterranean waters. In 1979, Gauthier and Breittmayer first named it Alteromonas aurantia to include it in the genus Alteromonas that was described seven years earlier, in 1972 by Baumann et al. In 1995, Gauthier et al renamed Alteromonas aurantia to Pseudoalteromonas aurantia to include it in their proposed new genus, Pseudoalteromonas, which they recommended splitting from Alteromonas.
Pseudoalteromonas citrea is a yellow-pigmented marine bacterium that is antibiotic-producing and was isolated from Mediterranean waters off Nice. Originally named Alteromonas citrea, nearly two decades later it was reclassified as part of the Genus Pseudoalteromonas.
Pseudoalteromonas peptidolytica is a marine bacterium isolated from the sea surrounding Yamato Island in the Sea of Japan.
Algicola sagamiensis is a marine bacterium isolated from sea water in Sagami Bay. It was originally named Pseudoalteromonas sagamiensis but was reclassified in 2007 into the genus Algicola.
