MRS2L

MRS2
Identifiers
Aliases	MRS2 , HPT, MRS2L, magnesium transporter, magnesium transporter MRS2
External IDs	MGI: 2685748; HomoloGene: 31983; GeneCards: MRS2; OMA:MRS2 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6p22.3 Start 24,402,908 bp [1] End 24,426,194 bp [1]
Gene location (Mouse) Chr. Chromosome 13 (mouse) [2] Band 13|13 A3.1 Start 25,171,466 bp [2] End 25,204,362 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in biceps brachii Skeletal muscle tissue of biceps brachii gastrocnemius muscle left ventricle right ventricle muscle of thigh right auricle of heart cerebellar hemisphere right hemisphere of cerebellum apex of heart Top expressed in spermatocyte retinal pigment epithelium spermatid neural layer of retina Paneth cell Epithelium of choroid plexus lacrimal gland substantia nigra ciliary body Region I of hippocampus proper More reference expression data BioGPS More reference expression data
Gene ontology Molecular function magnesium ion transmembrane transporter activity Cellular component integral component of membrane mitochondrial inner membrane membrane mitochondrion Biological process ion transport transmembrane transport lactate metabolic process mitochondrial magnesium ion transmembrane transport magnesium ion transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57380 380836 Ensembl ENSG00000124532 ENSMUSG00000021339 UniProt Q9HD23 Q5NCE8 RefSeq (mRNA) NM_001286264 NM_001286265 NM_001286266 NM_020662 NM_001013389 RefSeq (protein) NP_001273193 NP_001273194 NP_001273195 NP_065713 NP_001013407 Location (UCSC) Chr 6: 24.4 – 24.43 Mb Chr 13: 25.17 – 25.2 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Magnesium transporter MRS2 homolog, mitochondrial is a protein that in humans is encoded by the MRS2 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000124532 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021339 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: MRS2L MRS2-like, magnesium homeostasis factor (S. cerevisiae)".

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC   515316 . PMID   15342556.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi: 10.1038/nature02055 . PMID   14574404.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Zsurka G, Gregán J, Schweyen RJ (2001). "The human mitochondrial Mrs2 protein functionally substitutes for its yeast homologue, a candidate magnesium transporter". Genomics. 72 (2): 158–68. doi:10.1006/geno.2000.6407. PMID   11401429.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC   139146 . PMID   9110174.
• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID   8619474.