MXRA8

MXRA8
Identifiers
Aliases	MXRA8 , matrix remodeling associated 8, ASP3
External IDs	OMIM: 617293 MGI: 1922011 HomoloGene: 11500 GeneCards: MXRA8
Gene location (Human)
Chr.	Chromosome 1 (human)
End	1,361,777 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	155,928,545 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; tibial nerve; ; canal of the cervix; ; right coronary artery; ; gallbladder; ; ascending aorta; ; gastric mucosa; ; left coronary artery; ; left uterine tube; ; right lobe of thyroid gland;
	Top expressed in
	calvaria; ; right lung; ; ankle; ; body of femur; ; left lung; ; right lung lobe; ; molar; ; trachea; ; belly cord; ; sciatic nerve;
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function ;
Cellular component	integral component of membrane ; cell surface ; extracellular exosome ; membrane ; endoplasmic reticulum lumen ; nucleus ; cytoplasm ; plasma membrane ; bicellular tight junction ; cell junction ; cell projection ; ciliary membrane ;
Biological process	establishment of glial blood-brain barrier ; post-translational protein modification ; viral process ; cell adhesion ;
	Sources:Amigo / QuickGO
Orthologs
	54587
	74761
	ENSG00000162576
	ENSMUSG00000029070
	Q9BRK3
	Q9DBV4
	NM_032348 ; NM_001282582 ; NM_001282583 ; NM_001282584 ; NM_001282585
	NM_024263
	NP_001269511 ; NP_001269512 ; NP_001269513 ; NP_001269514 ; NP_115724
	NP_077225
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated April 12, 2024

Matrix remodeling associated 8 is a protein that in humans is encoded by the MXRA8 gene.^[5]

MXRA8 protein is a receptor for multiple arthritogenic alphaviruses, including chikungunya, Ross River, Mayaro and O'nyong nyong viruses.^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000162576 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029070 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Matrix remodeling associated 8" . Retrieved 2018-10-22.
↑ Zhang R, Kim AS, Fox JM, et al. (May 2018). "Mxra8 is a receptor for multiple arthritogenic alphaviruses". Nature. 557 (7706): 570–574. Bibcode:2018Natur.557..570Z. doi:10.1038/s41586-018-0121-3. PMC 5970976 . PMID 29769725.

MXRA8

Related Research Articles

References

Further reading