Majdine

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Majdine
Majdine.svg
Names
IUPAC name
Methyl 11,12-dimethoxy-19α-methyl-2-oxo-20α-formosanan-16-carboxylate
Systematic IUPAC name
Methyl (1′S,3R,4′aS,5′aS,10′aS)-6,7-dimethoxy-1′-methyl-2-oxo-1,2,4′a,5′,5′a,7′,8′,10′a-octahydro-1′H,10′H-spiro[indole-3,6′-pyrano[3,4-f]indolizine]-4′-carboxylate
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
PubChem CID
  • InChI=1S/C23H28N2O6/c1-12-14-10-25-8-7-23(18(25)9-13(14)15(11-31-12)21(26)30-4)16-5-6-17(28-2)20(29-3)19(16)24-22(23)27/h5-6,11-14,18H,7-10H2,1-4H3,(H,24,27)/t12-,13-,14-,18-,23+/m0/s1
    Key: TTZWEOINXHJHCY-UHJVZONPSA-N
  • InChI=1/C23H28N2O6/c1-12-14-10-25-8-7-23(18(25)9-13(14)15(11-31-12)21(26)30-4)16-5-6-17(28-2)20(29-3)19(16)24-22(23)27/h5-6,11-14,18H,7-10H2,1-4H3,(H,24,27)/t12-,13-,14-,18-,23+/m0/s1
    Key: TTZWEOINXHJHCY-UHJVZONPBK
  • C[C@H]1[C@@H]2CN3CC[C@]4([C@@H]3C[C@@H]2C(=CO1)C(=O)OC)C5=C(C(=C(C=C5)OC)OC)NC4=O
Properties
C23H28N2O6
Molar mass 428.485 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Majdine is a chemical compound, specifically an alkaloid isolated from Vinca minor and Vinca herbacea . [2] It has potential medicinal properties and is being studied for its various effects.

References

  1. ↑ "Majdine Mass Spectrum". massbank.eu.
  2. ↑ Gülçin, I.; Beydemir, S.; Topal, F.; Gagua, N.; Bakuridze, A.; Bayram, R.; Gepdiremen, A. (2012). "Apoptotic, antioxidant and antiradical effects of majdine and isomajdine from Vinca herbacea Waldst. and kit". Journal of Enzyme Inhibition and Medicinal Chemistry. 27 (4): 587–594. doi:10.3109/14756366.2011.604318. PMID   21883037.
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