Mallotojaponin C

Last updated
Mallotojaponin C
Mallotojaponin C.png
Names
IUPAC name
1,1’-{Methylenebis[2,6-dihydroxy-4-methoxy-5-(3-methyl-2-buten-1-yl)-3,1-phenylene]}diethanone
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
PubChem CID
Properties
C29H36O8
Molar mass 512.59 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Mallotojaponin C is a dimeric phlorogucinol found in Mallotus oppositifolius .

Mallotus oppositifolius is a plant species in the genus Mallotus found in Africa and Madagascar.

The bioassay-guided fractionation of an ethanol extract of the leaves and inflorescence of M. oppositifolius collected in Madagascar led to the isolation of the two new bioactive dimeric phloroglucinols mallotojaponins B and C, together with mallotophenone. These compounds show antiproliferative and antiplasmodial activities. [1]

Mallotojaponin B chemical compound

Mallotojaponin B is a dimeric phlorogucinol found in Mallotus oppositifolius.

Mallotophenone chemical compound

Mallotophenone is a dimeric phlorogucinol found in Mallotus oppositifolius or in Mallotus japonicus.

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Phloroglucinol chemical compound

Phloroglucinol is an organic compound with the formula C6H3(OH)3. It is a colorless solid. It is used in the synthesis of pharmaceuticals and explosives. Phloroglucinol is one of three isomeric benzenetriols. The other two isomers are hydroxyquinol (1,2,4-benzenetriol) and pyrogallol (1,2,3-benzenetriol). Phloroglucinol, and its benzenetriol isomers, are still defined as "phenols" according to the IUPAC official nomenclature rules of chemical compounds. Many such monophenolics are often termed "polyphenols" by the cosmetic and parapharmaceutical industries, but they cannot be by any scientifically-accepted definition.

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References

  1. Harinantenaina, Liva; Bowman, Jessica D.; Brodie, Peggy J.; Slebodnick, Carla; Callmander, Martin W.; Rakotobe, Etienne; Randrianaivo, Richard; Rasamison, Vincent E.; Gorka, Alexander; Roepe, Paul D.; Cassera, Maria B.; Kingston, David G. I. (2013). "Antiproliferative and Antiplasmodial Dimeric Phloroglucinols fromMallotus oppositifoliusfrom the Madagascar Dry Forest(1)". Journal of Natural Products. 76 (3): 388–93. doi:10.1021/np300750q. PMC   3606680 . PMID   23286240.