Mary Lou Guerinot

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Mary Lou Guerinot
Alma mater Cornell University, Dalhousie University
Known forResearch of metal metabolism in plants. Discovery of the proteins IRT1 and VIT1, which are responsible for the uptake of metal ions from soil in plants. Helped develop the field of ionomics.
Scientific career
Fields molecular genetics
Institutions Dartmouth College
Doctoral advisor David G. Patriquin

Mary Lou Guerinot is an American molecular geneticist who works as Ronald and Deborah Harris Professor in the Sciences at Dartmouth College. Her research concerns the cellular uptake and regulation of metal ions. [1]

Contents

Biography

Guerinot was born and grew up in Rochester, New York. She graduated from Cornell University in 1975, and earned her Ph.D. in marine biology in 1979 from Dalhousie University under the supervision of David G. Patriquin. [2] Her doctoral studies focused on the sea urchin-lobster-kelp ecosystem. [3]

After postdoctoral research at the University of Maryland and Michigan State University, she joined the Dartmouth faculty in 1985. In 1994, Guerinot became the first women to chair a science department at Dartmouth when she was appointed the chair Department of Biological Sciences. [4] She became the Ronald and Deborah Harris Professor in the Sciences in 2005. [5] In 2022, Guerinot joined the Salk Institute as Nonresident Fellow. [6]

She became a fellow of the American Association for the Advancement of Science in 2007, and of the American Society of Plant Biologists in 2009. [5] In 2016, Guerinot was elected to the National Academy of Sciences [7] and has been serving a three-year term on the academy's leadership council since 2023. [8]

Scientific contributions

Mary Lou Guerinot applies her research to solve problems in agriculture and human health, such as the need for fortified food crops and sustainable plant-based solutions for removing toxic metals from soil.

She helped discover the protein IRT1, [9] a high-affinity ion transporter that is responsible for the uptake of heavy metals from soil in plants. Guerinot was among the first plant biologists to use synchrotron X-ray fluorescence microprobe imaging to study the distribution of trace elements in plants, with which she identified VIT1, [10] an ion transporter that brings iron into a developing plant seed. Guerinot and her team used this technique to discover where iron is localized in seeds.

Guerinot helped develop the field of ionomics.

Awards and Honors

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References

  1. ↑ Faculty profile, Dartmouth College, 2 April 2013, retrieved 2016-05-14.
  2. ↑ "A career sparked by earth day". Dalhousie Alumni. 2020-04-28. Retrieved 2024-03-25.
  3. ↑ Viegas, Jennifer (2020-01-21). "Profile of Mary Lou Guerinot". Proceedings of the National Academy of Sciences. 117 (3): 1246–1248. Bibcode:2020PNAS..117.1246V. doi: 10.1073/pnas.1921933117 . ISSN   0027-8424. PMC   6983368 . PMID   31932429.
  4. ↑ Viegas, Jennifer (2020-01-13). "Profile of Mary Lou Guerinot". Proceedings of the National Academy of Sciences. 117 (3): 1246–1248. Bibcode:2020PNAS..117.1246V. doi: 10.1073/pnas.1921933117 . ISSN   0027-8424. PMC   6983368 . PMID   31932429.
  5. 1 2 Curriculum vitae (PDF), retrieved 2016-05-14.
  6. ↑ "Renowned plant molecular geneticist Mary Lou Guerinot joins Salk Institute as Nonresident Fellow". Salk Institute for Biological Studies. Retrieved 2024-03-20.
  7. ↑ National Academy of Sciences Members and Foreign Associates Elected, News from the National Academy of Sciences, National Academy of Sciences, May 3, 2016, retrieved 2016-05-14.
  8. ↑ "NAS Council". www.nasonline.org. Retrieved 2024-03-20.
  9. ↑ Korshunova, YO; Eide, D; Clark, WG; Guerinot, ML; Pakrasi, HB (1999). "The IRT1 protein from Arabidopsis thaliana is a metal transporter with a broad substrate range". Plant Molecular Biology. 40 (9): 37–44. doi:10.1023/a:1026438615520. PMID   10394943 – via pubmed.
  10. ↑ Kim, SA; Punshon, T; Lanzirotti, A; Li, L; Alonso, JM; Ecker, JR; Kaplan, J; Guerinot, ML (2006). "Localization of iron in Arabidopsis seed requires the vacuolar membrane transporter VIT1". Science. 314 (5803): 1295–1298. Bibcode:2006Sci...314.1295K. doi:10.1126/science.1132563. PMID   17082420 – via pubmed.
  11. ↑ "Graduate School Council". Guarini School of Graduate and Advanced Studies. 2018-03-02. Retrieved 2024-03-20.
  12. ↑ "Dennis R. Hoagland Award". American Society of Plant Biologists. Retrieved 2024-03-20.
  13. ↑ "Nine Professors Honored With Faculty Awards". Faculty of Arts and Sciences. 2016-01-25. Retrieved 2024-03-20.
  14. ↑ "Stephen Hales Prize". American Society of Plant Biologists. Retrieved 2024-03-20.


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