Maryanne Demasi | |
---|---|
Occupation(s) | Journalist, presenter |
Maryanne Demasi is an Australian investigative journalist and presenter best known for her controversial work with the Australian Broadcasting Corporation (ABC) Catalyst television program. Demasi challenges the scientific consensus on cholesterol, saturated fat and statins. She has argued that high-blood cholesterol and high saturated fat consumption do not cause or increase risk of cardiovascular disease and that cholesterol-reducing drugs such as statins are ineffective. These claims have been criticized by medical experts as dangerous and misleading. [1] [2] [3] [4]
Demasi became nationally prominent for television stories [5] that resulted in controversy, contributing to early rumours of the axing of Catalyst followed by an announcement of its planned restructuring and possible redeployment of staff. [6]
Demasi completed a doctorate in rheumatology at the University of Adelaide and worked for a decade at the Royal Adelaide Hospital as a research scientist. [7] She also worked as an advisor to the South Australian Government's Minister for Science and Information Economy. [7]
In 2003, Demasi co-authored a paper in the Journal of Biological Chemistry , on the "Effects of hypoxia on monocyte inflammatory mediator production" which was based on her PhD dissertation for the University of Adelaide. In 2017, an expression of concern was published to "inform readers that credible concerns have been raised regarding some of the data and conclusions". [8] The paper was retracted in 2018 after an investigation by the Journal determined that data had been duplicated. [9] [10] However, an administrative tribunal hearing on the matter, conducted by the University of Adelaide, exonerated Demasi of all allegations. "In response to three allegations, the 'duplication' represented the 'baseline' value for time course experiments and they were intended to indicate there is only one baseline for both the normoxia and hypoxia treatments. The expert witnesses at the hearing, and the panel agreed this was acceptable practice at the time, circa 2002, and did not constitute a breach in any code." The panel ruled that it could not substantiate any of the allegations made by the complainant. [11]
Demasi advocates low-carbohydrate diets and has spoken at events such as Low Carb Sydney in which she delivered a presentation "Statin Wars" in 2018. [12] [13] [14] In 2017, Demasi wrote an article with Robert H. Lustig and Aseem Malhotra arguing that the cholesterol hypothesis is "dead". [15] In 2021, Demasi co-authored a paper with Robert DuBroff challenging statin therapy. [16] As of 2022, Demasi is a writer for the Brownstone Institute, an organization that has been criticized by medical experts for spreading misinformation against vaccines. [17] [18]
Demasi produced and presented two controversial episodes on the science program Catalyst, called "The Heart of the Matter", in October 2013, which questioned the link between cholesterol, cholesterol-reducing medication and ill-health. [1] [19] A large number of individuals and professional organisations within the medical community responded to the show negatively, stating that its claims were misleading and ignored the scientific consensus. [2] The National Heart Foundation of Australia published an eight-page rebuttal of the claims presented in the program. [3]
Demasi was accused of bias by ABC's MediaWatch program [20] and received criticism from health specialists for incomplete and biased coverage of life-threatening health issues. [21] [22] [23] In response to these allegations, Demasi said that participants in the program had been presented with her material and agreed with her interpretation. [24] The National Heart Foundation responded, saying that Demasi had not presented the research, [25] ignored and misinterpreted the information provided and selectively edited quotes to invert their meaning. In May 2014 the ABC removed the two episodes from its website. [26] after an internal review found that both programs met the ABC editorial standards for factual accuracy, though a section in the second episode breached standards of impartiality. The report also found that the programs were not found to cause any undue harm to the public and took adequate steps to ensure people did not cease their medications without consulting their doctor. [27] Despite the finding of the ABC's report, the Medical Journal of Australia (MJA) claimed that there was a temporary increase in discontinuation of statins and a sustained decrease in the dispensing of statins immediately following the broadcast of the program. [28]
Demasi produced a report in a February 2016 episode of Catalyst called "Wi-Fried" on Wi-Fi and cellphone safety. In her report she detailed the scientific debate about health effects from low level exposures and she raised questions about the long term effects of low level microwave exposures in schools. Her report shows a school where the Wi-Fi routers are turned off when not in use to reduce microwave radiation exposure. Her report was described as unbalanced by Media Watch , [29] criticised by the Australian Radiation Protection and Nuclear Safety Agency (ARPANSA) [30] and in the media by groups and scientists who have long believed it is impossible for microwave radiation to have effects at low levels. [31] [32] [33] [34] [35] Demasi defended her report in an article in The Guardian [36] and responded to specific criticism in the Huffington Post. [37] Catalyst also defended the episode in a letter to Media Watch. [38] Demasi was stood down as a reporter and the program was placed under review. A public on-air apology statement was broadcast on the ABC on 5 July 2016, and the episode was withdrawn from the ABC's website.
Demasi has been awarded National Press Club of Australia prizes in 2008, 2009 and 2011 for "Excellence in Health Journalism". [39] [40] [41] In 2014 she was a finalist in the Association of International Broadcasting Awards for her Catalyst episode "Toxic Sugar", subsequently won by David Attenborough. [42]
Cholesterol is the principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Low-density lipoprotein (LDL) is one of the five major groups of lipoprotein that transport all fat molecules around the body in extracellular water. These groups, from least dense to most dense, are chylomicrons, very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL delivers fat molecules to cells. LDL is involved in atherosclerosis, a process in which it is oxidized within the walls of arteries.
Statins are the most common cholesterol-lowering drugs. Also known as HMG-CoA reductase inhibitors, they are a class of lipid-lowering medications that reduce illness and mortality in those who are at high risk of cardiovascular disease.
The Commonwealth Scientific and Industrial Research Organisation (CSIRO) is an Australian Government agency responsible for scientific research.
Hypercholesterolemia, also called high cholesterol, is the presence of high levels of cholesterol in the blood. It is a form of hyperlipidemia, hyperlipoproteinemia, and dyslipidemia.
Atorvastatin, sold under the brand name Lipitor among others, is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. For the prevention of cardiovascular disease, statins are a first-line treatment. It is taken by mouth.
Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. It is also used to decrease the risk of heart problems in those at high risk. It is taken by mouth.
Rosuvastatin, sold under the brand name Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. It is recommended to be used together with dietary changes, exercise, and weight loss. It is taken orally.
Pravastatin, sold under the brand name Pravachol among others, is a statin medication, used for preventing cardiovascular disease in those at high risk and treating abnormal lipids. It should be used together with diet changes, exercise, and weight loss. It is taken by mouth.
Catalyst is an Australian science journalism television program broadcast by the Australian Broadcasting Corporation (ABC). The program is currently the only science show on primetime television in Australia. Launched in 2001, it replaced Quantum which had ceased the previous year. Catalyst is regularly broadcast on ABC TV at 8:30 pm on Tuesdays and repeated at 6:00 pm on Sundays.
Fenofibrate, is an oral medication of the fibrate class used to treat abnormal blood lipid levels. It is less commonly used compared than statins because it treats a different type of cholesterol abnormality to statins. While statins have strong evidence for reducing heart disease and death, there is evidence to suggest that fenofibrate also reduces the risk of heart disease and death. However, this seems only to apply to specific populations of people with elevated triglyceride levels and reduced high-density lipoprotein (HDL) cholesterol. Its use is recommended together with dietary changes.
Hypocholesterolemia is the presence of abnormally low (hypo-) levels of cholesterol in the blood (-emia). A defect in the body's production of cholesterol can lead to adverse consequences as well. Cholesterol is an essential component of mammalian cell membranes and is required to establish proper membrane permeability and fluidity. It is not clear if a lower than average cholesterol level is directly harmful; however, it is often encountered in particular illnesses.
Familial hypercholesterolemia (FH) is a genetic disorder characterized by high cholesterol levels, specifically very high levels of low-density lipoprotein cholesterol, in the blood and early cardiovascular diseases. The most common mutations diminish the number of functional LDL receptors in the liver or produce abnormal LDL receptors that never go to the cell surface to function properly. Since the underlying body biochemistry is slightly different in individuals with FH, their high cholesterol levels are less responsive to the kinds of cholesterol control methods which are usually more effective in people without FH. Nevertheless, treatment is usually effective.
In Oceania, Google Street View is available in most parts of Australia and New Zealand.
Alirocumab, sold under the brand name Praluent, is a medication used as a second-line treatment for high cholesterol for adults whose cholesterol is not controlled by diet and statin treatment. It is a human monoclonal antibody that belongs to a novel class of anti-cholesterol drugs, known as PCSK9 inhibitors, and it was the first such agent to receive FDA approval. The FDA approval was contingent on the completion of further clinical trials to better determine efficacy and safety.
The Checkout was an Australian consumer affairs television series. The show's first series of 10 episodes premiered on 21 March 2013 on the Australian Broadcasting Corporation (ABC) television station ABC TV. A second series consisting of 16 episodes commenced airing on 20 February 2014. On 9 April 2015, a third series consisting of 12 episodes began airing. The series was renewed for a fourth series, which began airing on 7 April 2016 consisting of 12 episodes. The series returned for a fifth series, airing twelve episodes between 6 April 2017 and 29 June 2017. The Checkout, with a new look, logo, opening theme and art, still retaining original cast and segments, returned for a sixth season on 30 January 2018.
Aseem Malhotra is a controversial British cardiologist, public health campaigner, author, and advocate against the use of COVID vaccines. He campaigns for people to reduce sugar in their diet, promotes a low-carb and high-fat diet, and encourages the reduction of medical overprescribing. He was the first science director of Action on Sugar in 2014. He was listed as one of The Sunday Times 500 most influential people in 2016 and was twice recognized as one of the top fifty black and minority ethnic community member pioneers in the UK's National Health Service by the Health Service Journal. Malhotra is co-author of a book called The Pioppi Diet.
Nikki Stamp is an Australian cardiothoracic surgeon, writer and TV presenter.
Maryanne P. Confoy RSC is an Australian religious Sister of Charity who has also been a teacher and scholar, working primarily in the areas of ministry and spirituality.
Robert J. DuBroff is an American cardiologist who works in Albuquerque, New Mexico. He has challenged the lipid hypothesis and has disputed the efficiency of statin therapy. Dubroff also disputes the current saturated fat guidelines.
{{cite journal}}
: CS1 maint: multiple names: authors list (link){{cite journal}}
: CS1 maint: multiple names: authors list (link){{cite journal}}
: CS1 maint: multiple names: authors list (link)