The Merck Group, branded and commonly known as Merck, is a German multinational science and technology company headquartered in Darmstadt, with about 60,000 employees and a presence in 66 countries. The group includes around 250 companies; the main company is Merck KGaA in Germany. The company is divided into three business lines: Healthcare, Life Sciences and Electronics. Merck was founded in 1668 and is the world's oldest operating chemical and pharmaceutical company, as well as one of the largest pharmaceutical companies globally.
Serono was a biotechnology company headquartered in Geneva, Switzerland. It was acquired by the German pharmaceutical company Merck in 2006. The company was founded as the Serono Pharmacological Institute by Cesare Serono in 1906 in Rome, Italy. A key step in its development was the discovery of a method of extracting urinary gonadotropins by Dr. Piero Donini. Serono was incorporated in 1987 and the holding company, Ares-Serono S.A., changed its name to Serono S.A. in May 2000.
Sigma-Aldrich is an American chemical, life science, and biotechnology company owned by the multinational chemical conglomerate Merck Group.
Triton X-100 is a nonionic surfactant that has a hydrophilic polyethylene oxide chain and an aromatic hydrocarbon lipophilic or hydrophobic group. The hydrocarbon group is a 4-(1,1,3,3-tetramethylbutyl)-phenyl group. Triton X-100 is closely related to IGEPAL CA-630, which might differ from it mainly in having slightly shorter ethylene oxide chains. As a result, Triton X-100 is slightly more hydrophilic than Igepal CA-630 thus these two detergents may not be considered functionally interchangeable for most applications.
Waters Corporation is a publicly traded analytical laboratory instrument and software company headquartered in Milford, Massachusetts. The company employs more than 7,800 people, with manufacturing facilities located in Milford, Taunton, Massachusetts; Wexford, Ireland and Wilmslow, Cheshire. Waters has Sites in 35 countries globally including Frankfurt, Singapore, India, Germany and in Japan.
Merck Serono is a pharmaceutical company headquartered in Darmstadt, Germany, and a brand and division of Merck focused on biopharmaceuticals.
Novozymes A/S was a global biotechnology company headquartered in Bagsværd, outside of Copenhagen, Denmark. The company's focus was the research, development and production of industrial enzymes, microorganisms, and biopharmaceutical ingredients. The company merged with Chr. Hansen to form Novonesis in January 2024.
Levomefolic acid (INN, also known as L-5-MTHF, L-methylfolate and L-5-methyltetrahydrofolate and (6S)-5-methyltetrahydrofolate, and (6S)-5-MTHF) is the primary biologically active form of folate used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine. It is also the form found in circulation and transported across membranes into tissues and across the blood–brain barrier. In the cell, L-methylfolate is used in the methylation of homocysteine to form methionine and tetrahydrofolate (THF). THF is the immediate acceptor of one carbon unit for the synthesis of thymidine-DNA, purines (RNA and DNA) and methionine. The un-methylated form, folic acid (vitamin B9), is a synthetic form of folate, and must undergo enzymatic reduction by dihydrofolate reductase (DHFR) to become biologically active.
Aldrichimica Acta is a scientific journal published by Sigma-Aldrich. Established in 1968 in Milwaukee, Wi, Aldrichimica Acta publishes reviews in the field of synthetic organic chemistry, with each issue focusing on a special topic. The journal is open access. In 2015, the Acta was ranked #1 among journals in the field of organic chemistry by impact factor.
Sartorius AG is an international pharmaceutical and laboratory equipment supplier, covering the segments of Bioprocess Solutions and Lab Products & Services. In September 2021, Sartorius has been admitted to the DAX, Germany's largest stock market index. As a leading partner to the biopharmaceutical research and industry, Sartorius supports its customers in the development and production of biotech drugs and vaccines - from the initial idea in the laboratory to commercial production. Sartorius conducts its operating business in the two divisions Bioprocess Solutions and Lab Products&Services. The divisions bundle their respective businesses according to the same application areas and customer groups. The divisions share some of the infrastructure and central services.
LGC Biosearch Technologies is a biotechnology company headquartered in Hoddesdon, UK. It is a subsidiary of LGC Ltd specialising in nucleic acid production, PCR systems, and other molecular biology kits and services.
Carbolabs, Inc., is an American chemistry company specializing in reactions utilizing phosgene, founded by Joe Karabinos in 1967. Originally located in the basement of his home in Bethany, Connecticut, it wasn't until the following year that the business was moved into its own dedicated building. The company was purchased by Sigma Aldrich in 1998. In 2008 operations at the Bethany site were discontinued and were subsequently moved to the Sheboygan Falls, Wisconsin Sigma Aldrich manufacturing facility. Carbolabs uses phosgene to produce a wide array of chemicals including isocyanates, chloroformates, and isonitriles, although some reactions not involving phosgene such as the production of the fluorinating reagent DAST are also part of their established chemistries. As a subsidiary of Sigma Aldrich, a number of Aldrich products still bear "A Carbolabs Product" on their label.
Pittcon Editors’ Awards honoured the best new products on show at the Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, or Pittcon, for 20 years from 1996 having been established by Dr Gordon Wilkinson, managing editor of Analytical Instrument Industry Report. On 8 March 2015, the event returned to the Morial Convention Center in New Orleans and this was the last occasion when the awards were presented.
Tecemotide is a synthetic lipopeptide that is used as antigen in an investigational therapeutic cancer vaccine. The investigational therapeutic cancer vaccine is designed to induce a cellular immune response to cancer cells that express MUC1, a glycoprotein antigen that is widely over-expressed on common cancers such as lung cancer, breast cancer, prostate cancer, and colorectal cancer. The cellular immune response may lead to a rejection of tumor tissue expressing the MUC1 antigen.
Cerilliant Corporation, located in Round Rock, Texas, is a manufacturer of certified reference standards and certified reference materials providing products and services to forensic / toxicology, diagnostic/clinical, environmental, natural products, and pharmaceutical industries. Cerilliant is accredited to ISO Guide 34 & ISO/IEC 17025 and certified to ISO 13485 and ISO 9001:2008.
Serratia marcescens nuclease is an enzyme. This enzyme catalyses the following chemical reaction
Versum Materials, Inc. is an American company that manufactures chemical-mechanical planarization slurries, ultra-thin dielectric and metal precursors of film, formulated cleans and etching products, and delivery equipment for the semiconductor industry. It is a subsidiary of Merck Group.
ELGA LabWater is the laboratory water brand name of Veolia Water Solutions & Technologies. ELGA manufactures, supplies and services water purification systems for use in general, R&D, healthcare and clinical laboratories. Its offices and distributors are located in more than 60 countries.
Abituzumab is a humanized IgG2 monoclonal antibody (mAb) targeted at CD51 currently in development by Merck KGaA Darmstadt, Germany in an attempt to prevent bone lesion metastases in castration-resistant prostate cancer.
Elcin Barker Ergun is a business leader in the pharmaceutical industry. In September 2019 she was appointed chief executive officer and member of the board of directors of the Italian company Menarini Group.
