Myocardin is a protein that in humans is encoded by the MYOCD gene. [5] [6] [7]
Myocardin is a smooth muscle and cardiac muscle-specific transcriptional coactivator of serum response factor. When expressed ectopically in nonmuscle cells, myocardin can induce smooth muscle differentiation by its association with serum response factor (SRF; MIM 600589).[supplied by OMIM] [7]
Angiogenin (ANG) also known as ribonuclease 5 is a small 123 amino acid protein that in humans is encoded by the ANG gene. Angiogenin is a potent stimulator of new blood vessels through the process of angiogenesis. Ang hydrolyzes cellular RNA, resulting in modulated levels of protein synthesis and interacts with DNA causing a promoter-like increase in the expression of rRNA. Ang is associated with cancer and neurological disease through angiogenesis and through activating gene expression that suppresses apoptosis.
In the field of molecular biology, myocyte enhancer factor-2 (Mef2) proteins are a family of transcription factors which through control of gene expression are important regulators of cellular differentiation and consequently play a critical role in embryonic development. In adult organisms, Mef2 proteins mediate the stress response in some tissues. Mef2 proteins contain both MADS-box and Mef2 DNA-binding domains.
Transcription factor E2F4 is a protein that in humans is encoded by the E2F4 gene.
Transcription factor GATA-4 is a protein that in humans is encoded by the GATA4 gene.
Platelet-derived growth factor subunit A is a protein that in humans is encoded by the PDGFA gene.
Serum response factor, also known as SRF, is a transcription factor protein.
Myocyte-specific enhancer factor 2A is a protein that in humans is encoded by the MEF2A gene. MEF2A is a transcription factor in the Mef2 family. In humans it is located on chromosome 15q26. Certain mutations in MEF2A cause an autosomal dominant form of coronary artery disease and myocardial infarction.
Mediator of RNA polymerase II transcription subunit 14 is an enzyme that in humans is encoded by the MED14 gene.
Peroxisome proliferator-activated receptor gamma coactivator 1-beta is a protein that in humans is encoded by the PPARGC1B gene.
Thyroid hormone receptor-associated protein 3 is a protein that in humans is encoded by the THRAP3 gene.
MKL/megakaryoblastic leukemia 1 is a protein that in humans is encoded by the MKL1 gene.
TFIIA-alpha and beta-like factor is a protein that in humans is encoded by the GTF2A1L gene.
ETS domain-containing protein Elk-3 is a protein that in humans is encoded by the ELK3 gene.
Mediator of RNA polymerase II transcription subunit 17 is an enzyme that in humans is encoded by the MED17 gene.
Actin-binding Rho-activating protein is a protein that in humans is encoded by the ABRA gene. The mouse and rat homologues are known as STARS and MS1 respectively.
Mediator of RNA polymerase II transcription subunit 16 is an enzyme that in humans is encoded by the MED16 gene.
Homeobox protein Nkx-2.3 is a protein that in humans is encoded by the NKX2-3 gene.
SLC2A4 regulator is a protein that in humans is encoded by the SLC2A4RG gene.
MKL/myocardin-like protein 2 is a protein that in humans is encoded by the MKL2 gene.
Activating signal cointegrator 1 is a protein that in humans is encoded by the TRIP4 gene.
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