NCLN

NCLN
Identifiers
Aliases	NCLN , NET59, nicalin
External IDs	OMIM: 609156; MGI: 1926081; HomoloGene: 10604; GeneCards: NCLN; OMA:NCLN - orthologs
Gene location (Human) Chr. Chromosome 19 (human) [1] Band 19p13.3 Start 3,185,563 bp [1] End 3,209,575 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 C1 Start 81,322,083 bp [2] End 81,332,226 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon stromal cell of endometrium left adrenal gland right adrenal gland left adrenal cortex right adrenal cortex body of pancreas right lobe of liver granulocyte right hemisphere of cerebellum Top expressed in granulocyte right kidney interventricular septum lip spermatocyte muscle of thigh yolk sac tail of embryo ventricular zone neural layer of retina More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component integral component of membrane endoplasmic reticulum membrane membrane endoplasmic reticulum protein-containing complex Biological process regulation of protein-containing complex assembly protein destabilization regulation of signal transduction protein stabilization regulation of protein complex stability Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 56926 103425 Ensembl ENSG00000125912 ENSMUSG00000020238 UniProt Q969V3 Q8VCM8 RefSeq (mRNA) NM_020170 NM_001321463 NM_134009 RefSeq (protein) NP_001308392 NP_064555 NP_598770 Location (UCSC) Chr 19: 3.19 – 3.21 Mb Chr 10: 81.32 – 81.33 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Nicalin is a protein that in humans is encoded by the NCLN gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000125912 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000020238 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
6. "Entrez Gene: NCLN nicalin homolog (zebrafish)".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. Bibcode:2004Natur.428..529G. doi: 10.1038/nature02399 . PMID   15057824.
• Haffner C, Frauli M, Topp S, et al. (2005). "Nicalin and its binding partner Nomo are novel Nodal signaling antagonists". EMBO J. 23 (15): 3041–50. doi:10.1038/sj.emboj.7600307. PMC   514924 . PMID   15257293.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.