NECAP2

NECAP2
Identifiers
Aliases	NECAP2 , NECAP endocytosis associated 2
External IDs	OMIM: 611624; MGI: 1913397; HomoloGene: 9168; GeneCards: NECAP2; OMA:NECAP2 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1p36.13 Start 16,440,721 bp [1] End 16,460,078 bp [1]
Gene location (Mouse) Chr. Chromosome 4 (mouse) [2] Band 4|4 D3 Start 140,793,823 bp [2] End 140,805,668 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in oocyte granulocyte monocyte spleen lymph node secondary oocyte appendix stromal cell of endometrium right lung upper lobe of left lung Top expressed in stroma of bone marrow granulocyte lip right kidney gastrula blood lens yolk sac spermatocyte stomach More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 55707 66147 Ensembl ENSG00000157191 ENSMUSG00000028923 UniProt Q9NVZ3 Q9D1J1 RefSeq (mRNA) NM_001145277 NM_001145278 NM_018090 NM_025383 RefSeq (protein) NP_001138749 NP_001138750 NP_060560 NP_079659 Location (UCSC) Chr 1: 16.44 – 16.46 Mb Chr 4: 140.79 – 140.81 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Adaptin ear-binding coat-associated protein 2 is a protein that in humans is encoded by the NECAP2 gene. ^{[5] [6] [7]}

Interactions

NECAP2 has been shown to interact with AP1G1. ^[8]

References

1. GRCh38: Ensembl release 89: ENSG00000157191 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000028923 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ritter B, Philie J, Girard M, Tung EC, Blondeau F, McPherson PS (Oct 2003). "Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif". EMBO Rep. 4 (11): 1089–95. doi:10.1038/sj.embor.embor7400004. PMC   1326374 . PMID   14555962.
6. Ritter B, Blondeau F, Denisov AY, Gehring K, McPherson PS (Oct 2004). "Molecular mechanisms in clathrin-mediated membrane budding revealed through subcellular proteomics". Biochem. Soc. Trans. 32 (Pt 5): 769–73. doi:10.1042/BST0320769. PMID   15494011.
7. "Entrez Gene: NECAP2 NECAP endocytosis associated 2".
8. Mattera R, Ritter B, Sidhu SS, McPherson PS, Bonifacino JS (Feb 2004). "Definition of the consensus motif recognized by gamma-adaptin ear domains". J. Biol. Chem. 279 (9): 8018–28. doi: 10.1074/jbc.M311873200 . PMID   14665628.

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Hartley JL, Temple GF, Brasch MA (2000). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Hattori A, Okumura K, Nagase T, Kikuno R, Hirosawa M, Ohara O (2000). "Characterization of long cDNA clones from human adult spleen". DNA Res. 7 (6): 357–66. doi: 10.1093/dnares/7.6.357 . PMID   11214971.
• Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Mattera R, Ritter B, Sidhu SS, McPherson PS, Bonifacino JS (2004). "Definition of the consensus motif recognized by gamma-adaptin ear domains". J. Biol. Chem. 279 (9): 8018–28. doi: 10.1074/jbc.M311873200 . PMID   14665628.
• Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415-8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.