NLRP9

Last updated
NLRP9
Identifiers
Aliases NLRP9 , CLR19.1, NALP9, NOD6, PAN12, NLR family, pyrin domain containing 9, NLR family pyrin domain containing 9
External IDs OMIM: 609663 MGI: 2675377 HomoloGene: 18530 GeneCards: NLRP9
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_176820

NM_194058

RefSeq (protein)

NP_789790

NP_918947

Location (UCSC) Chr 19: 55.71 – 55.74 Mb Chr 7: 19.73 – 19.81 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

NLRP9, short for NOD-like receptor family pyrin domain containing 9, is an intracellular protein that is expressed in the ovaries, testes, oocytes, and preimplantation embryos of mammals that is likely involved in reproductive processes. [5] [6] [7] It is also known as NALP9, NOD6, PAN12, and CLR19.1, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.

Related Research Articles

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<span class="mw-page-title-main">NLRP7</span> Protein-coding gene in the species Homo sapiens

NACHT, LRR and PYD domains-containing protein 7 is a protein that in humans is encoded by the NLRP7 gene.

<span class="mw-page-title-main">HOXD1</span> Protein-coding gene in the species Homo sapiens

Homeobox protein Hox-D1 is a protein that in humans is encoded by the HOXD1 gene.

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<span class="mw-page-title-main">NLRP12</span> Protein-coding gene in the species Homo sapiens

NACHT, LRR and PYD domains-containing protein 12 is a protein that in humans is encoded by the NLRP12 gene.

<span class="mw-page-title-main">GNA11</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">NLRP4</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">NLRP5</span> Protein-coding gene in the species Homo sapiens

NLRP5, short for NOD-like receptor family pyrin domain containing 5, is an intracellular protein that plays a role in early embryogenesis. NLRP5 is also known as NACHT, LRR and PYD domains-containing protein 5 (NALP5), Mater protein homolog (MATER), PYPAF8, PAN11, and CLR19.8, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors known to mammals.

<span class="mw-page-title-main">NLRP6</span> Protein-coding gene in the species Homo sapiens

NLRP6, short for NOD-like receptor family pyrin domain containing 6, is an intracellular protein that plays a role in the immune system. It is also known as NALP6, PYPAF5, PAN3, and CLR11.4, and is one of 14 pyrin domain containing members of the NOD-like receptor family of pattern recognition receptors. As with several other NOD-like receptors, NLRP6's role in immunity is related to its ability to regulate caspase-1 and NF-κB activity.

<span class="mw-page-title-main">NLRP8</span> Protein-coding gene in the species Homo sapiens

NLRP8, short for NOD-like receptor family pyrin domain containing 8, is an intracellular protein that is expressed in the ovaries, testes, and preimplantation embryos of mammals. It is also known as NALP8, NOD16, PAN4, and CLR19.2, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors.

<span class="mw-page-title-main">NLRP10</span> Protein-coding gene in the species Homo sapiens

NLRP10, short for NOD-like receptor family pyrin domain containing 10, is an intracellular protein of mammals that functions in apoptosis and the immune system. It is also known as NALP10, NOD8, PAN5, Pynod, and CLR11.1, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors, although it differs from other NOD-like receptors by lacking the characteristic leucine-rich repeat domain. It is also believed that it helps regulate the inflammatory response. NLRP10 reduces inflammatory and innate immune responses by inhibiting the activity of two proteins associated with the inflammasome; caspase-1 and PYCARD.

<span class="mw-page-title-main">NLRP13</span> Protein-coding gene in the species Homo sapiens

NLRP13, short for NOD-like receptor family pyrin domain containing 13, is an intracellular protein of mammals. It is also known as NALP13, NOD14, PAN13, and CLR19.7, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors. The function of NLRP13 is currently unknown.

<span class="mw-page-title-main">NLRP14</span> Protein-coding gene in the species Homo sapiens

NLRP14, short for NOD-like receptor family pyrin domain containing 14, is an intracellular protein of mammals associated with a role in spermatogenesis. It is also known as NALP14, NOD5, GC-LRR, Nalp-iota, PAN8, and CLR11.2, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors. NLRP14 is found exclusively in the testes where it is expressed within spermatogonia, spermatocytes and spermatids.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000185792 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000060508 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Dalbiès-Tran R, Papillier P, Pennetier S, Uzbekova S, Monget P (August 2005). "Bovine mater-like NALP9 is an oocyte marker gene". Mol. Reprod. Dev. 71 (4): 414–21. doi:10.1002/mrd.20298. PMID   15892040. S2CID   33157680.
  6. Ponsuksili S, Brunner RM, Goldammer T, et al. (March 2006). "Bovine NALP5, NALP8, and NALP9 genes: assignment to a QTL region and the expression in adult tissues, oocytes, and preimplantation embryos". Biol. Reprod. 74 (3): 577–84. doi:10.1095/biolreprod.105.045096. PMID   16339045. S2CID   2784688.
  7. Tian X, Pascal G, Monget P (2009). "Evolution and functional divergence of NLRP genes in mammalian reproductive systems". BMC Evol. Biol. 9 (1): 202. Bibcode:2009BMCEE...9..202T. doi: 10.1186/1471-2148-9-202 . PMC   2735741 . PMID   19682372.

Further reading