NOL8

NOL8
Identifiers
Aliases	NOL8 , C9orf34, NOP132, bA62C3.3, bA62C3.4, nucleolar protein 8
External IDs	OMIM: 611534; MGI: 1918180; HomoloGene: 41210; GeneCards: NOL8; OMA:NOL8 - orthologs
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q22.31 Start 92,297,358 bp [1] End 92,325,636 bp [1]
Gene location (Mouse) Chr. Chromosome 13 (mouse) [2] Band 13 A5|13 25.36 cM Start 49,806,554 bp [2] End 49,832,492 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon testicle body of pancreas body of uterus skin of abdomen canal of the cervix left ovary tibial nerve right ovary spleen Top expressed in zygote spermatocyte tail of embryo genital tubercle secondary oocyte spermatid seminiferous tubule primary oocyte Rostral migratory stream hand More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding nucleic acid binding RNA binding Cellular component nucleolus nucleus ribonucleoprotein complex Biological process rRNA processing protein localization to nucleolus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55035 70930 Ensembl ENSG00000198000 ENSMUSG00000021392 UniProt Q76FK4 Q3UHX0 RefSeq (mRNA) NM_001256394 NM_017948 NM_001330722 NM_001081350 NM_001271397 RefSeq (protein) NP_001243323 NP_001317651 NP_060418 NP_001243323.1 NP_001258326 Location (UCSC) Chr 9: 92.3 – 92.33 Mb Chr 13: 49.81 – 49.83 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Nucleolar protein 8 is a protein that in humans is encoded by the NOL8 gene. ^{[5] [6]}

Interactions

NOL8 has been shown to interact with RRAGA ^[7] and NIP7. ^[7]

References

1. GRCh38: Ensembl release 89: ENSG00000198000 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021392 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
6. "Entrez Gene: NOL8 nucleolar protein 8".
7. Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T (Feb 2004). "A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D". J. Biol. Chem. 279 (9): 8343–50. doi: 10.1074/jbc.M305935200 . PMID   14660641.

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Sekiguchi T, Hirose E, Nakashima N, Ii M, Nishimoto T (2001). "Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B". J. Biol. Chem. 276 (10): 7246–57. doi: 10.1074/jbc.M004389200 . PMID   11073942.
• Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T (2004). "A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D". J. Biol. Chem. 279 (9): 8343–50. doi: 10.1074/jbc.M305935200 . PMID   14660641.
• Jinawath N, Furukawa Y, Nakamura Y (2004). "Identification of NOL8, a nucleolar protein containing an RNA recognition motif (RRM), which was overexpressed in diffuse-type gastric cancer". Cancer Sci. 95 (5): 430–5. doi: 10.1111/j.1349-7006.2004.tb03227.x . PMC   11159714 . PMID   15132771. S2CID   40861858.
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.