NPTXR

Last updated
NPTXR
Identifiers
Aliases NPTXR , NPR, neuronal pentraxin receptor
External IDs OMIM: 609474; MGI: 1920590; HomoloGene: 8620; GeneCards: NPTXR; OMA:NPTXR - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_058178
NM_014293

NM_030689

RefSeq (protein)

NP_055108

n/a

Location (UCSC) Chr 22: 38.82 – 38.84 Mb Chr 15: 79.67 – 79.69 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Neuronal pentraxin receptor is a protein that in humans is encoded by the NPTXR gene. [5] [6]

Contents

This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat protein pentraxin is thought to mediate neuronal uptake of synaptic material and the presynaptic snake venom toxin, taipoxin. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for human and mouse, based on strong sequence conservation amongst these species. [6]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000221890 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022421 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Andersson KB, Florholmen G, Winer LH, Tonnessen T, Christensen G (Feb 2006). "Regulation of neuronal type genes in congestive heart failure rats". Acta Physiol (Oxf). 186 (1): 17–27. doi:10.1111/j.1748-1716.2005.01503.x. PMID   16497176. S2CID   46217094.
  6. 1 2 "Entrez Gene: NPTXR neuronal pentraxin receptor".

Further reading